DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pka-C1 and Pka-C2

DIOPT Version :9

Sequence 1:	NP_476977.1	Gene:	Pka-C1 / 34284	FlyBaseID:	FBgn0000273	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_733397.2	Gene:	Pka-C2 / 43644	FlyBaseID:	FBgn0000274	Length:	354	Species:	Drosophila melanogaster

Alignment Length:	353	Identity:	164/353 - (46%)
Similarity:	227/353 - (64%)	Gaps:	9/353 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 TSNKKVDAAETVKEFLEQAKEEFEDKWR---RNP-TNTAALDDFERIKTLGTGSFGRVMIVQHKP 67
            ||....::.|.....|:....|||::|.   ::| ||   |:::.....||.||||.||:|:.|.
  Fly     5 TSQYVFNSKEDYNVILDNMSREFEERWNHQTQSPYTN---LENYITRAVLGNGSFGTVMLVREKS 66

  Fly    68 TKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMF 132
            .|:|||.|::.|:.:|:||||.|..|||.:|.|.:||||:.|....|....||::|..|.|||:|
  Fly    67 GKNYYAAKMMSKEDLVRLKQVAHVHNEKHVLNAARFPFLIYLVDSTKCFDYLYLILPLVNGGELF 131

  Fly   133 SHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGR 197
            |:.|:|.:|:|.|:||||||:.||.||:|.:.|:||||||||:|:|.:||:|:|||||.|||.||
  Fly   132 SYHRRVRKFNEKHARFYAAQVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTKRVDGR 196

  Fly   198 TWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFAD--QPIQIYEKIVSGKVRF 260
            |.|||||||||||||:..:.|||:|||||.|:||||..||..||...  ..|.:|.||.....:.
  Fly   197 TSTLCGTPEYLAPEIVQLRPYNKSVDWWAFGILVYEFVAGRSPFAIHNRDVILMYSKICICDYKM 261

  Fly   261 PSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPG 325
            ||:|.|.|:.|:.:|:|||.:||.||...|.:|:|:..||...||..|..:::.||:.|...|..
  Fly   262 PSYFTSQLRSLVESLMQVDTSKRLGNSNDGSSDVKSHPWFQGVDWFGILNQEVTAPYQPTISGAE 326

  Fly   326 DTSNFDDYEEEALRISSTEKCAKEFAEF 353
            |.|||:::|.:....|...:..:.||.|
  Fly   327 DLSNFENFEFKDRYKSRINRHPELFANF 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C1	NP_476977.1	STKc_PKA	44..333	CDD:271111	147/290 (51%)
Pka-C2	NP_733397.2	PKc_like	43..334	CDD:328722	147/290 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440851
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0616
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S234
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D277423at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24353
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.800