DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pka-C1 and Sgk1

DIOPT Version :9

Sequence 1:	NP_476977.1	Gene:	Pka-C1 / 34284	FlyBaseID:	FBgn0000273	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	XP_006227785.1	Gene:	Sgk1 / 29517	RGDID:	3668	Length:	525	Species:	Rattus norvegicus

Alignment Length:	335	Identity:	135/335 - (40%)
Similarity:	206/335 - (61%)	Gaps:	20/335 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 NPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRI-LQ 99
            ||  .|...||..:|.:|.||||:|::.:||..:.:||:|:|.|:.::|.|:.:|.::|:.: |:
  Rat   184 NP--HAKPSDFHFLKVIGKGSFGKVLLARHKAEEAFYAVKVLQKKAILKKKEEKHIMSERNVLLK 246

  Fly   100 AIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLD 164
            .::.||||.|.:.|:....||.||:|:.|||:|.||::...|.||.:|||||:|..|..|||.|:
  Rat   247 NVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLN 311

  Fly   165 LIYRDLKPENLLIDSQGYLKVTDFGFAK---RVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWA 226
            ::||||||||:|:||||::.:||||..|   ...|.|.|.||||||||||::..:.|::.||||.
  Rat   312 IVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWC 376

  Fly   227 LGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGV 291
            ||.::|||..|.|||::....::|:.|::..::...:..:..:.||..|||.|.|||.| .|...
  Rat   377 LGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLG-AKDDF 440

  Fly   292 NDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFD-DYEEE------------ALRISST 343
            .:||:..:|:..:|..:..|||..||.|...||.|..:|| ::.||            .|..:|.
  Rat   441 MEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTEEPVPSSIGRSPDSILVTASV 505

  Fly   344 EKCAKEFAEF 353
            ::.|:.|..|
  Rat   506 KEAAEAFLGF 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C1	NP_476977.1	STKc_PKA	44..333	CDD:271111	125/293 (43%)
Sgk1	XP_006227785.1	S_TKc	192..449	CDD:214567	111/257 (43%)
Sgk1	XP_006227785.1	STKc_SGK	196..518	CDD:270727	130/321 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910