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Protein Alignment Pka-C1 and Prkg1

DIOPT Version :9

Sequence 1:	NP_476977.1	Gene:	Pka-C1 / 34284	FlyBaseID:	FBgn0000273	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_035290.1	Gene:	Prkg1 / 19091	MGIID:	108174	Length:	686	Species:	Mus musculus

Alignment Length:	342	Identity:	147/342 - (42%)
Similarity:	208/342 - (60%)	Gaps:	15/342 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGNNATTSNKKVDAAETVKEFLEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQH 65
            :|.....|||..:.||.      :||.|.|..:..|    ..|.||..|.|||.|.||||.:||.
Mouse   340 IGGLDDVSNKAYEDAEA------KAKYEAEAAFFAN----LKLSDFNIIDTLGVGGFGRVELVQL 394

  Fly    66 KPTKD-YYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGG 129
            |..:. .:|||||.|:.:|..:|.||..:||:|:|.....|:|.|...|||:..|||::|...||
Mouse   395 KSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGG 459

  Fly   130 EMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRV 194
            |:::.||..|.|.:..:|||.|.:|.||.|||...:||||||||||::|.:||.|:.||||||::
Mouse   460 ELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKI 524

  Fly   195 --KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSG- 256
              ..:|||.||||||:||||||:||::.:.|:|:||:|:||:..|.|||....|::.|..|:.|
Mouse   525 GFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGI 589

  Fly   257 -KVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPR 320
             .:.||.....:..:|::.|.:.:.::|.||||.||.||:..|||...:|..:.:..:..|.||.
Mouse   590 DMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPS 654

  Fly   321 CKGPGDTSNFDDYEEEA 337
            ...|.||||||.:.|::
Mouse   655 VASPTDTSNFDSFPEDS 671

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.