DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pka-C1 and F47F2.1

DIOPT Version :9

Sequence 1:	NP_476977.1	Gene:	Pka-C1 / 34284	FlyBaseID:	FBgn0000273	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_508671.2	Gene:	F47F2.1 / 180673	WormBaseID:	WBGene00018569	Length:	398	Species:	Caenorhabditis elegans

Alignment Length:	356	Identity:	157/356 - (44%)
Similarity:	230/356 - (64%)	Gaps:	18/356 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 NNATTSNKKVDAAETVKEFLEQAKEEFEDKWRRNPTNTA-ALDDFERIKTLGTGSFGRVMIVQHK 66
            ||.:..|.:|:          :..||...|....||..: :|...|||.|:|.|:||||.:.:.|
Worm    56 NNNSRGNNQVN----------ELAEETHMKLSITPTRESFSLSQLERIITIGKGTFGRVELARDK 110

  Fly    67 PTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEM 131
            .|..:||:|:|:.::||.::|.:|..||||:|..::.||:|.:....||:::|||::|:||||||
Worm   111 ITGAHYALKVLNIRRVVDMRQTQHVHNEKRVLLQLKHPFIVKMYASEKDSNHLYMIMEFVPGGEM 175

  Fly   132 FSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKG 196
            ||:||....||...:||||::||.|.||:|.|.::|||||||||::..:|::|:.||||||.::.
Worm   176 FSYLRASRSFSNSMARFYASEIVCALEYIHSLGIVYRDLKPENLMLSKEGHIKMADFGFAKELRD 240

  Fly   197 RTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFP 261
            ||:|:||||:|||||.:...|:||.|||||||:|:|||..|.|||......:||:.|:..|::||
Worm   241 RTYTICGTPDYLAPESLARTGHNKGVDWWALGILIYEMMVGKPPFRGKTTSEIYDAIIEHKLKFP 305

  Fly   262 SHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGD 326
            ..|....|||::.||:||.|:|.|.:|.|..|:|:.|||...:|......::|.|.:|....|||
Worm   306 RSFNLAAKDLVKKLLEVDRTQRIGCMKNGTQDVKDHKWFEKVNWDDTLHLRVEPPIVPTLYHPGD 370

  Fly   327 TSNFDDYEEEALRISSTEKCAKE----FAEF 353
            |.|||||||:.   :....|::.    |||:
Worm   371 TGNFDDYEEDT---TGGPLCSQRDRDLFAEW 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C1	NP_476977.1	STKc_PKA	44..333	CDD:271111	139/288 (48%)
F47F2.1	NP_508671.2	PTZ00263	80..379	CDD:140289	144/298 (48%)
F47F2.1	NP_508671.2	PKc_like	88..379	CDD:304357	141/290 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D277423at33208
OrthoFinder	1	1.000	-	-		FOG0000539
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100326
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820