DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pka-C1 and prkx

DIOPT Version :9

Sequence 1:	NP_476977.1	Gene:	Pka-C1 / 34284	FlyBaseID:	FBgn0000273	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	XP_002941045.1	Gene:	prkx / 100494406	XenbaseID:	XB-GENE-6046135	Length:	369	Species:	Xenopus tropicalis

Alignment Length:	294	Identity:	155/294 - (52%)
Similarity:	220/294 - (74%)	Gaps:	0/294 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 LDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLV 107
            ||||:.:.|:|||:||||.:|:.|..|.|:|:|::....|::|||.:|..|||.:|:.:..||||
Frog    57 LDDFDTVATVGTGTFGRVHLVKEKMGKQYFALKVMSIPDVIRLKQEQHVHNEKSVLKEVNHPFLV 121

  Fly   108 SLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKP 172
            .|.:...|:..|||::|||||||:||:||.:|||:.....||:.:|:.|.||||..:::||||||
Frog   122 KLFWTSHDDRFLYMLMEYVPGGELFSYLRNMGRFNNSTGLFYSTEIICAIEYLHSKEIVYRDLKP 186

  Fly   173 ENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAG 237
            ||:|:|.:|::|:|||||||::..|||||||||||||||:|.|||:.:||||||||:|::||.:|
Frog   187 ENILLDKEGHIKLTDFGFAKKLSDRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSG 251

  Fly   238 YPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFAS 302
            :||||.|.|..||:||::||:.||.|....:|||::.||.||.|:|.||:|.|.:|:|..:||.|
Frog   252 FPPFFDDNPFGIYQKILAGKIDFPRHLDLYVKDLIKKLLVVDRTRRLGNMKNGADDVKRHRWFRS 316

  Fly   303 TDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEE 336
            .||..:..:|::.|.||:....||||||:.|.|:
Frog   317 IDWDTVPPRKLKPPIIPKVTHEGDTSNFEAYPED 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C1	NP_476977.1	STKc_PKA	44..333	CDD:271111	152/288 (53%)
prkx	XP_002941045.1	STKc_PRKX_like	58..349	CDD:270763	153/290 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D277423at33208
OrthoFinder	1	1.000	-	-		FOG0000539
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920