DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Apoltp and apobb.1

DIOPT Version :9

Sequence 1:	NP_995670.2	Gene:	Apoltp / 34283	FlyBaseID:	FBgn0032136	Length:	4333	Species:	Drosophila melanogaster
Sequence 2:	XP_005160686.1	Gene:	apobb.1 / 321166	ZFINID:	ZDB-GENE-030131-9732	Length:	3739	Species:	Danio rerio

Alignment Length:	4497	Identity:	846/4497 - (18%)
Similarity:	1468/4497 - (32%)	Gaps:	1549/4497 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGGLKPQAAIWLLLL---IAHTQAVRENPLKDPRICGRPQCDSKSAKFNYGEQLYKYQYTVAVRT 62
            |||.|    :.||||   ||.:.|..|.|           | ..:.:|   :...||:||....:
Zfish     1 MGGTK----LCLLLLLCAIALSYAQEEEP-----------C-LLAKRF---KSFQKYEYTYETES 46

  Fly    63 EFAGSGD-NSSDLLLKSDLEIFFPKPCEGYLRINDAKLYDTLDELNDNESDSSEKTKEYDYYDNL 126
            ..|.:|. |......|.::|:  |:.|...:...:.:|.|.:|      .|:..|    ..:.:.
Zfish    47 LNALNGAINGPKARCKVEIEV--PRICSYIVHTTECELSDVID------VDAEGK----PIFMSS 99

  Fly   127 ANEESESQNYDNMHPKSSDFNVDLTKNLLRFAFHDGLISEVCPQEQETPWVLNIKKGILSAFQNT 191
            |..|:              |...:.||.|:|........::.|:..|...:||.|:|::||....
Zfish   100 AGAEA--------------FKAAMAKNPLKFTVEGDNDIKLFPENDEPANILNFKRGLISALAAP 150

  Fly   192 MMRFDVDANTTETDVSGQCQVQYALEDTDSSYVTIRKTKDINSC------RQRYATHSVLQTTPY 250
            ::  :.|.|.....|.|.|:..|::.........:...:|:::|      :...:..:::....|
Zfish   151 VL--EEDRNRRMPTVYGMCRTDYSVNARQDIATDVVLNRDLSNCDKFSPVKDHTSPLALITGMQY 213

  Fly   251 TFRDDKTIWPILKSQSHCNLTIDNNV--YKEIKCLETHLLVPFS-NASSGALTTSTSRLKLDGVE 312
            ....      :::|...||...||:.  .....|.|.|:|:||| ....|........|.|.||.
Zfish   214 PLAQ------LIRSSQTCNYKFDNDQKHMTSASCSEKHMLLPFSYKGEHGVSNVGKQALTLVGVS 272

  Fly   313 SYSAGEFLEQNPELVERRATLVFDHTPA-VKPSH--DEIKAARELLVEMCRVGFPNIQREFIDVF 374
            .|:.                .:|||..| :|..|  |.|.:...:   ..:....:|.|:..|:.
Zfish   273 VYNG----------------RIFDHNEANMKTLHLDDSIDSVHPI---QDKDAILSILRDLNDLS 318

  Fly   375 -TNFLQTSKSLDYKTLSVLLQRSASTCEQGRNHLLE-SLPFI-----------GSTASYKVMR-- 424
             |...:....|.:|.:|.:.:.||.:........|| |.|.:           .::|..:|:|
Zfish   319 ETTNGENRAHLAHKLISTIRKMSAESLSAALPEALEISRPLVYQALFQCGTPECTSAILRVLRTF 383

  Fly   425 -------DQIINEKLTKQMAHDWMTALSFITRPDEETLETFHSILEYAKNRLDAE--YTLGATAV 480
                   |..:             .|:..:..|..:.:|   .:||.||.:....  |.|.
Zfish   384 DRSSVEIDAAV-------------YAMGMVPNPSRDLVE---EMLEMAKFKSSKPIYYALS---- 428

  Fly   481 VHSFCKHHEACEENLRVQQIINLLETEFLNLYNLFK-GE-RRTRERMVILLKGLGN----IGVVS 539
                    .|.:....|::.:. .|.:.:..|.|.: |: ...:|.:.:.|:.:||    :|..|
Zfish   429 --------NAVKRLYEVEKSVT-PEIKAVADYTLEQIGDCTGNQEHVYLSLRVIGNMAAAVGAAS 484

  Fly   540 SAFAEQLQWIIREDEAPVDIRLHGILAFRRVDCA-RHRSYFLDNYGNYTLNSELRIYSYLQAMRC 603
            .|....:...|.:..|..:::...|..||..... ..|...:....:.....:.|:.:||..|:.
Zfish   485 PALKSAVIQCINQPAASPEVQQAAIQVFRLTSVPDEGREVLMKVIFDKAAPIQKRVAAYLIVMKD 549

  Fly   604 PDYISVGVIKSILEHEEINQVGSFVWSHLTNLAKSNS----PVRIEAQGLLLNDELSERFKMDIR 664
            |....:..:.:.|.:.:..|..|||.|||.|:..|.:    .:|::....|..:|:|.  ..|..
Zfish   550 PQPTELAQLVAALPNNKNCQAMSFVNSHLRNILSSTTSETGELRVKILNALQGNEIST--STDPT 612

  Fly   665 KFSRNYEHSLFFDEYNFGTTTDANVIFGTDSYLPRIASVNFTADLFGQSVNFFEFTARAEGLEEL 729
            ||||||:..          :.:.||||.::..||....:..|.:.||..|:.||.....:|||
Zfish   613 KFSRNYKIG----------SLEGNVIFESEELLPNEVILEMTLNAFGYDVDMFEIGLNGKGLE-- 665

  Fly   730 AANAFGPKGPLSGQLLRKKLSFLNRWLGNESAEEDDTLENLLSLDNLRLKRKAQEQARASEEEVD 794
                                               .|::.|:.:|.. .:...|:....:.::|.
Zfish   666 -----------------------------------PTVDALIGIDGF-FRDTMQKTINYAADKVP 694

  Fly   795 EDYDFEESL-----EGNKRQKRDVSTTRKQEIDRNVDSLGYKLKYDYNNPRAQFGLRVFGNDLRY 854
            ...|..:|:     ...|.||...|..:  ||..||:.|..|||.. :||.|...||:.|.::.|
Zfish   695 RGNDIMQSMFPTLWNNIKMQKAPQSIVK--EITNNVNKLIQKLKVQ-DNPEAMIYLRLLGAEMGY 756

  Fly   855 F---NVESLVEVMALAAK----FNPFQQAKNVLSGKEFTYTKSRVFLDASYTVPLAVGLPLAIHA 912
            .   :||.:....||..|    ..|....:|:.|..........||:|..:.:|...|:||.:..
Zfish   757 LKTNDVEDMAYSAALLTKSLLNMFPTDFLRNLYSSVNNNLFLHYVFMDNEFYLPTGTGIPLRVAL 821

  Fly   913 FG--ASSI--DLRVSGNLDEMDPPTDWHFDVEGQFKPSVSVDVITTMQTDM-FWEQSGIKVKSNL 972
            .|  |..:  .|:::.::.|:            .|.||..|:.:|.:...: .:.:||:::.:|:
Zfish   822 SGTFAPGVKGGLKLARDMSEV------------AFMPSAGVEFVTEVGALLPEYVESGLEMHTNI 874

  Fly   973 YSNSELVAKLKVRGRNLVSFSFDLPRDKNEIFSVRSEL--LVQKREEQLPQAGIANRSANSTCTW 1035
            |..|.|..|:.|..:.. ..:...|:...::.||.:.|  :.....:::|.  :|.......||
Zfish   875 YHESGLKVKVAVTNKQF-KLTIPTPKTSTKLISVSNSLYSVTGTEIKRIPP--LAEHVKARKCT- 935

  Fly  1036 PVLDQAIGLQMCSHYSVPDLSNA--TEIYPSLLLAGPLNFSL-ILKKSDLSAKKYVFEYKWDQQE 1097
            |.:.   |.|.|   .|...|||  .:..|...|.|...|:: |....::|:.....:|.:|.::
Zfish   936 PFIP---GFQYC---GVMQYSNAFSNDAAPYFPLTGDSKFAIEIHPTGEVSSYTATADYAYDGKD 994

  Fly  1098 EDNNFSLVFTTPGSKVPRVLVANVTKVPDAFNASVAFVNGPNRVSAGCSYDGNPDFRRLDIYLDT 1162
            :...|       |.|...:...::.|        :.|......|||....   ||:
Zfish   995 DTVTF-------GLKAEGITFESIVK--------LTFDRQNYEVSADVQI---PDY--------- 1032

  Fly  1163 NGNRSLDLGMELRRH-------QDFTAWIYNPRMLLAINGVNITGLA------------------ 1202
                  ||...:|.|       .|.|..|....|...:...::.|||
Zfish  1033 ------DLEAGIRVHAVDRKAQSDATHSIQIDLMKKNVPEASLIGLAKIGSMKDAMLQVQLLIPN 1091

  Fly  1203 --------------GTVKVNEKNGIKQHDVD-------LSFETKKLQAVIKGNV---VQSEITT- 1242
                          ..:||..::.||..::.       |.::.::::|.:..:|   :.:.|||
Zfish  1092 FETDAKVTATLKNTDELKVELESDIKLPEMTSSIQKMILKYDAEEIEAEVSSDVTTEIHNIITTD 1156

  Fly  1243 ---------------------------------------STNMTIKYRFQANKIEEINFAGKLVN 1268
                                                   |.|:......:...:.|..|..||..
Zfish  1157 AIKATFNDILDQEIGTSDKKIRDVLTQFVEASNAYLEQFSPNIPYVQELRIPALPEFTFPKKLFL 1221

  Fly  1269 N----------------------GDKSKTEYRGNMKLQTSAYPKLN------------------F 1293
            |                      |.|:..::.....|:|   |.||                  |
Zfish  1222 NAEGAAKYKFGQNYYTITIPVPLGGKTSRDFNLPAALET---PVLNVPQLDLQVKSINIPLPVFF 1283

  Fly  1294 ASESTWLSLQGHTEGMITYNNAPDYVN--------------PNYTSLVRL-------IFARSHSE 1337
            ..||..|||....:..::...:.::.:              |.|::::.:       :.:.....
Zfish  1284 IPESLSLSLPLVAKAEVSSKLSSNFYDMEAKASAGSELVDKPTYSAMIEVTGTSPVDLLSFKIEG 1348

  Fly  1338 DSFLDG-------TQTRASLELKLPRSKIDY--------RILVKHKEH--------IKNGTEHNV 1379
            .:||.|       |:.::||..||..:.::|        :|.:|....        :|...||..
Zfish  1349 STFLVGRLGESLKTEMKSSLNHKLLEASVNYFEEITTGEKITMKSSSKMEAKSPFGLKISLEHTG 1413

  Fly  1380 IVGLKYTPEKEITG----LFSVH----------------LPRRNLFAIDAYMNVTVPEFNSCTAS 1424
            .|||   .|.||:|    |.|:.                ||.:....||              :|
Zfish  1414 QVGL---DEDEISGDGNLLGSIKAGPLNGEVALRQSLILLPFKPELKID--------------SS 1461

  Fly  1425 LKVN-EKATKDYII---FINGSW-FTGHSVAVKANYKDRSSRVQALHHLKMIVESPSFNITSLNI 1484
            |||: |:...:.||   |.||.. ||..|.|.:.|          |.|:             ..:
Zfish  1462 LKVDLEQIQAENIIEAAFANGELSFTSKSTAFQDN----------LIHV-------------AEL 1503

  Fly  1485 IYRRKQLLIFYDIQAKYDQDPYGLTIQYASNAHNRNTNAEVRLKVKERDYWINAKLLSEQPKLLQ 1549
            .|:..||.:..|.:||    .:||.||..:.|     :|...|        :|.|:.:....|..
Zfish  1504 AYKESQLALKSDARAK----AFGLNIQNVAEA-----SASFNL--------VNVKIDTNVDTLFG 1551

  Fly  1550 LEIHMDKIRDVHIQVGLLNVDKRKELSLELKWDANRDPSQ------------RLGLLAEYNSPGT 1602
                 :::|...|.....|       .|::|.||:.:..:            |.||:.
Zfish  1552 -----NRVRSQFIAALDAN-------GLDVKSDASANLDEHTASHMCSLSLTRNGLVT------- 1597

  Fly  1603 KHYDGNLMITYPERTIHFGFNSFTGGPKYFG---KVHASWSINEVIEFEYEAGILPGHTLHNWVK 1664
               .|:.::..|:..:... |.|.|.....|   .|.......||             |:.|
Zfish  1598 ---IGSTLLECPDMPLTLQ-NKFNGALDTSGLSLSVETKGKFVEV-------------TIEN--- 1642

  Fly  1665 AELRTPFDGWRVNSLDAGIYSLKNLILVNSTLFWADDQKLQVGYKSDYDVNDQLMSFDVRFGINS 1729
                       .|||.|.:.|:..:...||     ||..    |..|:.:  ||..:.....|::
Zfish  1643 -----------TNSLSASLSSVDFISKANS-----DDGT----YVHDFSL--QLQPYSTSLKISN 1685

  Fly  1730 TIRDIPTINVKVKHWMDVKKVDTELYLGYSGQNDTFNTYSMDSSWEIEKNQRYNNYSGLVHLVSP 1794
            .:.   .:|:|:.:....|.      |.|:.  |...::.:.|..:..||.....|..||
Zfish  1686 NLN---ALNIKLINEAQFKA------LPYAA--DLTGSWKLSSGTDELKNTYEIKYEDLV----- 1734

  Fly  1795 FKGYEKGGLV-----AHFSLSDQRVVSG-------AASLNFDLREFTLTMNGYVKKFTDNM-LTV 1846
              ...|.||.     :|.|.:.:..|:|       .::.|.....|...::.....|..|: ..|
Zfish  1735 --ATAKCGLTGKLMGSHMSQNTEIEVAGLSVTYGSESNFNSQYLRFNSDLHAAAVPFRFNVDAMV 1797

  Fly  1847 NITTPLEKFGTINAR-FGLNEKKRHAVA-----EVRAPTAALGVEVLADIKNLLNFDVKL-SVAT 1904
            |....|..:|..:|: :.....|...:|     |.|..|.   ..:..|:....|.|.|: :|.|
Zfish  1798 NADGDLYLYGKQSAQVYSKFLMKAEPLAFAHSHECRVSTT---YNLYDDLVFETNLDNKIDTVLT 1859

  Fly  1905 PIESFQQAAIFALFN-------------PER--VDMRGLWNNVTLGFTGVWHMQNITDFEYSYHV 1954
            |.|......:.:.||             |||  |:|.|         :.:.::.|..|.:...|.
Zfish  1860 PSEQKATVRVKSKFNNHEFNKDLSAYNTPERLGVEMSG---------SIITNIFNTVDSDNQDHF 1915

  Fly  1955 FTPLAGFEENG--------------FIVQLLK---------------RKEFVFQLHGKMSNYKLG 1990
            |:....:::|.              |.:|.:|               |:|.:.::. |::.|
Zfish  1916 FSAFLKYDKNSNSRALSLPFIDEFPFDLQHMKLAVLRIVEAMQSYINREEIIVEIQ-KLATY--- 1976

  Fly  1991 VKINGEPKSDLVNQLGSNK------MELEMLYD-------------ADFKP----LNAETD---- 2028
                   .||.||:|...:      .:|..||:             .:.||    |..|.|
Zfish  1977 -------VSDFVNELNLEEKIIKFSKDLTALYEDYGITLDDLEASLMNLKPVLLKLVTELDTYVV 2034

  Fly  2029 -------------YKPDADEEYF-----SYFTNFQVDTLVWPTI------VGNVDIQEI------ 2063
                         ...||..:.|     |:...:.|..:|...|      :..:|:..|
Zfish  2035 EIEKIVREIITSGTPSDAAIQRFTDILNSFNEKYDVKAIVLTVIEAIEKFLREIDVMSIKGSREV 2099

  Fly  2064 ----IDFYLVVGHVELPQGKVE------------------------FKDRLHYPDYINVHNLLTV 2100
                :|.|..:      :.|||                        |.....:.||.:  ||
Zfish  2100 FKQYVDEYFAI------KSKVEEILSELKQFVANFDQEKFTEDVKNFVTSARFRDYAD--NL--- 2153

  Fly  2101 TTPFAVAK----NIKSIVEYHVDL------NFNAFYERVKFIV----NDDKDNT-----QELGFV 2146
                 |||    .|..|:|....|      ..||.|..|:.|:    .|.|..|     .||...
Zfish  2154 -----VAKIPTEQISKILEKAKQLLNLLGNRMNAIYTNVREILVKSGVDKKIETLLKKVVELIKK 2213

  Fly  2147 FNYTALQDNVKPKAHDVQVTLLTPY-----------------EMLHEI---------YVHGHIEL 2185
            ||   :::.||..| |...::|||.                 |::.::         |:.   ..
Zfish  2214 FN---IEETVKTLA-DTLKSILTPVTELVDKAINYLKTTEAKEIIEDLNNCLNHCIKYIR---SF 2271

  Fly  2186 DDNAY------------------------KGNISAVTAHTHL---SMAASIENEDNFLETSV--- 2220
            |.||:                        :..:.|:....:.   ||:|.||..:......|
Zfish  2272 DYNAFVDEANQKIKKLTNDLYTMSLSLEIRQKLEAIREFVNYALSSMSACIEKLEKVKVVDVVKK 2336

  Fly  2221 -------GIQLETDAIPHYGCQVYFKKDFSAVDKAIDIRFEV----------------------- 2255
                   .:.::|:|:         .:|...:...||||.|:
Zfish  2337 FSDIVDSVVFIDTEAL---------IEDLRKILADIDIREEIQKFLKHASSISTKVVTTATDACS 2392

  Fly  2256 ----------TDNGTLNQLHISTDWHTDPSYIVNANGRIKTTMLPLQMASTSVLVIQGQNPHLNF 2310
                      .|...:|:|....|             |:||.   |:.|...:       |...|
Zfish  2393 AVMQVIQNILKDQAVVNELKQICD-------------RVKTV---LRTAEFKI-------PSFIF 2434

  Fly  2311 DLNLLSQNGQSIAYGARANKKKDVFNIEVWTPMKNFRNISMHGTAIRSPRDPGRYDVSGF----- 2370
            .|.                   |:....:...:||.:.|::..:.|         |:.||
Zfish  2435 PLT-------------------DLVVPSIKISLKNLQEINLPSSLI---------DLPGFTILQY 2471

  Fly  2371 -------------------LYRNMATYEVTGAV-RMTNSLPI----DVVLRVQPKAGGRDGVIEL 2411
                               |...:|.:|:..|| .:...|.|    |:.....|:.    .:.|:
Zfish  2472 YTVPPIRVEYADIKQGLLDLLHFIANFEIMPAVENIFGDLRIVYMPDISAITLPEI----SLPEI 2532

  Fly  2412 NIHEAGPKKI-RFSFSAIEDGKMCQMSGGYSVSKTNGAMDFSVLVESTEPEIARINFYGNLSPNS 2475
            ::.|. ||.| :..||                             :.|.||.........:....
Zfish  2533 SLPEI-PKYISKHKFS-----------------------------DLTIPEFTLPGVPTEVMVPC 2567

  Fly  2476 EGSLVGDLSLETPWKALGIDTVHLHSDVGFLNKG---------GHIV----GEYKIGQYIGRGSC 2527
            .|.|.|::.:..|       ..::.:.|.|||..         |||.    .||.:.:|....:.
Zfish  2568 FGKLYGEVRVTIP-------IFNMRTTVEFLNSTESAETPQFVGHITSHGSSEYDLLKYTLDSTA 2625

  Fly  2528 ------LWSWILAEDMQLVLENYLERPNAKPRIVHASAKYQNPGQTFTQLQAGGRLSVDSKWNLD 2586
                  :...||||.:               :|.|:.                  |::|.:.::.
Zfish  2626 RVAMPKMSRVILAETL---------------KITHSV------------------LAIDHQSSVS 2657

  Fly  2587 VNG-SAEYKSVDDFKFRVITALPLPVGDRHQLSASYQGNVISQQFNNPDFVL--------EASYE 2642
            :.| ||:..|....|   ||            |::|..|:::..|    |.|        :.:|.
Zfish  2658 LYGLSAQASSKSTMK---IT------------SSTYNANIVNTAF----FALAGGISANIKTTYN 2703

  Fly  2643 SFEAQNKLLSRISYKN----ATNNLKGLGHVEWGKIQNLSVVEGDFELLHKQGAQREFSAKIITP 2703
            .....:...|...|.|    ..:.||.|..:|.....::||:|...::..|..     |:.||||
Zfish  2704 DKLNADLWNSEYYYGNDIILKQDGLKLLLTMEEEAKGHISVLEKSDDITGKSS-----SSIIITP 2763

  Fly  2704 KFKNEHTFALTGSYDLEKSGHHNVVGSL----------DYPASRRIT------------------ 2740
            .     ||:|..|.| ..|...|:..|:          |:.||...|
Zfish  2764 T-----TFSLIISVD-SSSSVSNIKKSIKADGVALSYVDFTASIEGTSDSELFLLNAAGKADLRQ 2822

  Fly  2741 -------DLDVSVSSLSNMHGIFNSTLPTFLNVSWLKTDFNFTTNNGKSYRYCRCFWPQDTAYFK 2798
                   |||...:.|  :.|.|.|.             |||...            |.:...
Zfish  2823 MKVEMKADLDTKYAGL--LSGTFTSA-------------FNFLVQ------------PFEVVL-- 2858

  Fly  2799 LNSNYDSDSSNFNHNLNGNVEIEVPLATRHRADIVYGLQKRRNQDAGNVKVVYN--EKQVLDGKY 2861
                      :|.:..|..:.:..||:.:      ..||       .|..|:.|  |:.:..|..
Zfish  2859 ----------DFKNKANTKLNLVEPLSAK------IDLQ-------NNYTVILNSDEQMLSTGLL 2900

  Fly  2862 KRLEQAKAPIYKETTDISLENEVKPLGIHFVSTRDA---------SDPAGSQD--VKHIEIYELR 2915
            .|..|     ||.:.:.:|.|.....||:.....:|         |.||...:  ...|||.|:.
Zfish  2901 ARFNQ-----YKYSHNFTLANNEDEAGIYAAVNGEANLEFLTIPFSIPAMELETLTMVIEIPEIS 2960

  Fly  2916 NTQNFNLTG-----------------------ELHSRATLKAQDFKVVA---------------- 2941
            |...:..||                       :|.|..:.|:..|.:.|
Zfish  2961 NINLYEQTGLKHVLTDFDQAIDVDAKMVYQKNDLTSELSFKSSIFNLNANAGFYQKDNPVIRFGV 3025

  Fly  2942 IHPNRAVVLSTKYEDVSPEVVRHHSKLELS-------------ETAWIGYNLELGNFSKVGNESQ 2993
            |..:....|..|.|..|....:...||..|             .||    .:.|.||    ..:.
Zfish  3026 ITASEFESLKAKLEGTSSLSTKSGFKLANSLLLENRHIEGTHESTA----TMNLNNF----EVTL 3082

  Fly  2994 SFALEIFYPKRN---LSSSGQYYMT---DTNFNSDLSFQWLGGNYDQQPKIIHSNLQWKAEPLHR 3052
            |.|.:   .|.|   |:::..:.:|   ..|..:|.:|:.   :|:....||....:..||.:.:
Zfish  3083 SMATD---AKMNLPILTANANHQLTADNKANPKADSTFKM---DYNFDVPIIKLVGKGNAETILK 3141

  Fly  3053 GDREHRTIALTVAHPLLEKDIN--------CKAT-------YYRG--LRDLLRT--HLTIDYSEY 3098
            |:.....|:   |..|::.:|:        .|.|       |..|  ||..|:|  :..::|.::
Zfish  3142 GEGTRTFIS---AETLIKSNIDGTFLDRGILKGTLNYDESLYVNGNSLRYALKTGGNGDLNYGDF 3203

  Fly  3099 P-----DQLIELGAQLTDRYSELGHTNY------TFHVYGKHIA-SELDVQLNGTLAAMNSYYKT 3151
            .     |:.:.:.......|:.:..|:.      :|:..|.|.: :.||:.|..:|
Zfish  3204 KVAFDVDENLSVETANEHVYATMKFTSNNEANVGSFNTKGVHSSQATLDMALLKSL--------- 3259

  Fly  3152 ESTAHYKRDIF-PARYGKFLALLDVNKRELEYERQSPFHAVRLHLLPTIRYPIYGLNATI---WD 3212
              .|..|.|:. |:.:|: |::.:..|.:|...:|      ::.:|.||:.|:|..:...   .:
Zfish  3260 --VADMKIDLSQPSTFGE-LSIFETMKVDLSAPKQ------KIDILSTIKSPVYTTDVRAKLDGN 3315

  Fly  3213 TPDTNHSGYIYMDILERYA-----RMDFNLTEDASQNLQ----MVGYIPDTRSAFLDIWRNYEEI 3268
            .||       |..:|:..|     |:.::|....|..::    :||     .:|.|    .:::.
Zfish  3316 APD-------YKTVLKASATSPVVRLQYDLDSSMSSTMENGALVVG-----ANAVL----THQDF 3364

  Fly  3269 RVIDVSSYLKMN-HSRL----ITGRFHWRPSIRQEVREKIQAVGKSVYSSFSEGIDFWIKSIYTE 3328
             .:|:|:.::|: .|.:    ||.:.....::|              |::.|:||.   .|:.|.
Zfish  3365 -TMDISNAIRMSERSHILNVDITSQTFTDVNLR--------------YAARSDGIS---GSVSTP 3411

  Fly  3329 TTESMG--VVWNTAKEYNRDFI--------DDIGQLSVLEEDLADLR-LFVNQSYEANDFYIKNV 3382
            .:..:|  :..|...:.|....        ||:..|||......|.: |.|..:.:|.....:.:
Zfish  3412 GSGLLGFQLQGNIPSQMNARLYCRYAFAPDDDVDILSVRAVPKGDEKVLLVTGNIKAAQSMFEGL 3476

  Fly  3383 VNFTLTILDELAIRDHIESLPKIFSELWQAMGDSGKALRNSIVWLIETIKTTYNNLLDAVARFFH 3447
            :|                :|.||..:|.....:.|.|..   :::.:.:....:|.|.|..|
Zfish  3477 MN----------------TLEKISFKLAGLAREYGLAFP---IFVADDVYGVISNGLSAARR--- 3519

  Fly  3448 GESLVYISGLLEKGIAKYDSFIKDLHIKFIKYIENLWHKTWTLAENHWKAVLKRFEPHLFKMISF 3512
                      ...|:::.....:::.:...|.|:       .|.:|   |::...|...:|:...
Zfish  3520 ----------ATPGVSELSQLFRNVVVTSQKTIQ-------VLIDN---AIVLVKEISQYKLPGM 3564

  Fly  3513 IETTAWNLSKE----VFDFIYKRTNELAESPYFNKVSSFTADAERLYRDFKANDAITNIKKYSTI 3573
            .|.|...:.|:    |.:.:....|.|  ..||:.:                      :..::||
Zfish  3565 NEATLAEICKKIQLVVVEMLRNFGNNL--EVYFSPI----------------------MDNFNTI 3605

  Fly  3574 AWNFVKEKYFKLVPFGAELNEVLTE----IWQEIKELEKIDQV-QIMVQKYYEVMAKVDWVADEL 3633
            ...|...|...:..|...:..:|..    |...:|::|..|.| :.:.|...||:.|.....|::
Zfish  3606 QLTFPNGKVMTVAEFQQNVQSILRSNLVMIADAMKQIESPDVVLKKLGQTLQEVVEKGQEFVDKM 3670

  Fly  3634 QLEHRLHQVYGLVRNKFRNYAMNALETADMYREAKTKFVFD---PEVGIIDLEQKLPMSWHAFNE 3695
            .|. .|..:...: |.|....|..:|      :.....:|.   |.:.|.::.|.:....:|.|.
Zfish  3671 NLS-LLEDIAAAI-NTFYQELMKIIE------DISEAVIFGFSIPAIKIYEISQNIGKVLNANNG 3727

  Fly  3696 TPRFE-EIPEYQ 3706
            ..:|| .:|.:|
Zfish  3728 IHQFELPLPFFQ 3739

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Apoltp	NP_995670.2	LPD_N	49..633	CDD:214755	123/627 (20%)
		DUF1943	665..1012	CDD:286281	83/365 (23%)
		DUF1081	1029..1122	CDD:283982	21/95 (22%)
		VWD	3741..3908	CDD:295339
		C8	3951..4014	CDD:285899
apobb.1	XP_005160686.1	Vitellogenin_N	32..579	CDD:279663	124/631 (20%)
		DUF1943	613..912	CDD:286281	82/362 (23%)
		DUF1081	934..1016	CDD:283982	22/103 (21%)
		EzrA	1921..2312	CDD:283753	72/424 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I8881
eggNOG	1	0.900	-	-		E1_KOG4338
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6550
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.810