Protein Alignment GlcAT-S and B3GAT3

DIOPT Version :10

• Sequence 1: NP_001162922.1
• Gene: GlcAT-S / 34282
• FlyBaseID: FBgn0032135
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_036332.2
• Gene: B3GAT3 / 26229
• HGNCID: 923
• Length: 335
• Species: Homo sapiens
• Alignment Length: 246
• Identity: 102/246 - (41%)
• Similarity: 134/246 - (54%)
• Gaps: 24/246 - (9%)

  Fly   207 LPVIYFVTPTYPRREQIPELTRLAHTLLHIPRLHWLVADDQEKCNDYMDTLLYRFGMPFTHMV-- 269
            ||.||.|||||.|..|..||.||:.||..:||||||:.:|.|.....:..||...|:.|||:|
Human    74 LPTIYVVTPTYARLVQKAELVRLSQTLSLVPRLHWLLVEDAEGPTPLVSGLLAASGLLFTHLVVL 138

  Fly   270 SPMPSKFRNEKPA---PRGVANRRAALQWIRQHN------------LTNGILYFGDDDNTYDLRL 319
            :|...:.|..:|.   ||||..|..||.|:|...            .|.|::||.||||||...|
Human   139 TPKAQRLREGEPGWVHPRGVEQRNKALDWLRGRGGAVGGEKDPPPPGTQGVVYFADDDNTYSREL 203

  Fly   320 FSEIRKTQRVSMFPVGLIADYGVSGPVVRKGKVVAFLDSWVAGRRWPVDMAGFAVNLEYMAQYPY 384
            |.|:|.|:.||::||||:......||.|:.|:||.|..:|...|.:|||||||||.|..:...|
Human   204 FEEMRWTRGVSVWPVGLVGGLRFEGPQVQDGRVVGFHTAWEPSRPFPVDMAGFAVALPLLLDKP- 267

  Fly   385 VNMPYKP----GYEEDLFLRSIGLQMNLIEPRGNNCTEILVWHTQTKSKKL 431
             |..:..    |:.|...|..: :....:|||..|||.:|||||:|:..|:
Human   268 -NAQFDSTAPRGHLESSLLSHL-VDPKDLEPRAANCTRVLVWHTRTEKPKM 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlcAT-S	NP_001162922.1	GlcAT-I	208..427	CDD:132995	99/239 (41%)
B3GAT3	NP_036332.2	GlcAT-I	75..313	CDD:132995	100/240 (42%)
		Interaction with galactose moiety of substrate glycoprotein	243..252		3/8 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	312..335		1/5 (20%)