DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GlcAT-S and glct-5

DIOPT Version :9

Sequence 1:	NP_001162922.1	Gene:	GlcAT-S / 34282	FlyBaseID:	FBgn0032135	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_493160.2	Gene:	glct-5 / 183771	WormBaseID:	WBGene00008293	Length:	304	Species:	Caenorhabditis elegans

Alignment Length:	255	Identity:	86/255 - (33%)
Similarity:	131/255 - (51%)	Gaps:	25/255 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   193 RQFMQDKPQSDYVQLPVIYFVTPTYPRREQIPELTRLAHTLLHIPRLHWLVADDQEKCNDYMDTL 257
            |:.|:...::.......|..|||||.|..::|::.|||:||.|:..|||:|.:|.......:..|
Worm    43 RKIMEPSSKNSDASNRTIIVVTPTYKRITRLPDMIRLANTLAHVKNLHWIVVEDGYGIVPAVREL 107

  Fly   258 LYRFGMPFTHMVSPMPSKFRNEKPAP-RGVANRRAALQWI--------RQHNLTNGILYFGDDDN 313
            |.:..:.:|:|.      .:..|..| ||...|..||::|        |:|   :.::||.||||
Worm   108 LEKTNLSYTYMA------HKTAKGYPTRGWYQRTMALRYIRSSWSKILREH---DAVVYFADDDN 163

  Fly   314 TYDLRLFSE-IRKTQRVSMFPVGLIADYGVSGPVVRKGKVVAFLDSWVAGRRWPVDMAGFAVNLE 377
            .||:|||:: ||....:.::.|||:....|..|.|...||..|...|...||:.|||||||:||:
Worm   164 AYDVRLFTDYIRNVNTLGVWAVGLVGGAIVEAPKVVNHKVTGFNVRWSPNRRFAVDMAGFAINLK 228

  Fly   378 YMAQYPYV---NMPYKPGYEEDLFLRSIGLQMNLIEPRGNNCT---EILVWHTQTKSKKL 431
            |:.....|   :.....|..|...:..|||.:..|:|.|.:.|   :|:||||:|...::
Worm   229 YILNSDAVFGKDCKRGEGAPETCLIEDIGLDLEDIKPFGYDATKVQDIMVWHTKTSPPEI 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GlcAT-S	NP_001162922.1	GlcAT-I	208..427	CDD:132995	83/234 (35%)
glct-5	NP_493160.2	GlcAT-I	58..285	CDD:132995	84/235 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3762
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D385244at33208
OrthoFinder	1	1.000	-	-		FOG0000504
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10896
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X314
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.830