Protein Alignment gcm2 and GCM1

DIOPT Version :10

• Sequence 1: NP_609302.1
• Gene: gcm2 / 34280
• FlyBaseID: FBgn0019809
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_003634.2
• Gene: GCM1 / 8521
• HGNCID: 4197
• Length: 436
• Species: Homo sapiens
• Alignment Length: 408
• Identity: 144/408 - (35%)
• Similarity: 199/408 - (48%)
• Gaps: 71/408 - (17%)

  Fly    67 WDINDAIVPHVPDQEFDEFNEWSDGHVRHIYSLHNEEAKKHISGWAMRNTNNHNVNILKKSCLGV 131
            |||||..:|. ..::.|.|.||.|.:.:||||..::.|::|:|.||||||||||..|||||||||
Human    16 WDINDVKLPQ-NVKKTDWFQEWPDSYAKHIYSSEDKNAQRHLSSWAMRNTNNHNSRILKKSCLGV 79

  Fly   132 LVCSQHCTLPNGSKINLRPAICDKARRKQEGKACPNKSCRGGRLEIKPCRGHCGYPVTHFWRHSG 196
            :||.:.|....|.||.||||||||||:||:.|.|||  | .|.|::.|||||.|:|||:||||.|
Human    80 VVCGRDCLAEEGRKIYLRPAICDKARQKQQRKRCPN--C-DGPLKLIPCRGHGGFPVTNFWRHDG 141

  Fly   197 NAIFFQAKGVHDHLRPDPKNSSVSKRAFGRVPLAGKSANGSVAKKSVIAGLVKQAKQQHSLISKV 261
            ..||||:||.|||.:|:.|..:.::||..:|..|..|.:.|:...:....|..:.:.|.||....
Human   142 RFIFFQSKGEHDHPKPETKLEAEARRAMKKVNTAPSSVSLSLKGSTETRSLPGETQSQGSLPLTW 206

  Fly   262 LKRPAVSNP---LAHTALDIYQYNACGKCAGYSHCTCSY-------LDDSTTA-------RSHQL 309
            ..:..|..|   ..|...:..|.|:...|..:|.   ||       |.|.|:.       ...:|
Human   207 SFQEGVQLPGSYSGHLIANTPQQNSLNDCFSFSK---SYGLGGITDLTDQTSTVDPMKLYEKRKL 268

  Fly   310 SQSSNYGTNS-WPLSGS-------ESSAPCETAANVFTVNHQHIT----YNYPIYHATPAAATAA 362
            |.|..|.:.. .|.|.|       :..|..:.||    :...|:.    .||| :..|....:.:
Human   269 SSSRTYSSGDLLPPSASGVYSDHGDLQAWSKNAA----LGRNHLADNCYSNYP-FPLTSWPCSFS 328

  Fly   363 PSKSPSLPYACSISELAAYQQ-----------------SSSGNSFAMGVPVHGHTQCQAVAYDSS 410
            ||::.|.|:         |||                 :.:||.:...|.|..::..|:.|| .|
Human   329 PSQNSSEPF---------YQQLPLEPPAAKTGCPPLWPNPAGNLYEEKVHVDFNSYVQSPAY-HS 383

  Fly   411 PQLATPEPEFINYSQIKH 428
            ||   .:|....|:...|
Human   384 PQ---EDPFLFTYASHPH 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gcm2	NP_609302.1	GCM	82..222	CDD:397602	81/139 (58%)
GCM1	NP_003634.2	GCM	30..167	CDD:397602	81/139 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	171..202		6/30 (20%)