Protein Alignment gcm2 and GCM1

DIOPT Version :9

• Sequence 1: NP_609302.1
• Gene: gcm2 / 34280
• FlyBaseID: FBgn0019809
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: XP_016866879.1
• Gene: GCM1 / 8521
• HGNCID: 4197
• Length: 498
• Species: Homo sapiens
• Alignment Length: 482
• Identity: 155/482 - (32%)
• Similarity: 217/482 - (45%)
• Gaps: 106/482 - (21%)

  Fly    28 VQPQSQSTHSVHPGP---SPGQQQAGGSMTM-------PSSSTGKGKR----------------- 65
            :.|.|..::.....|   |||.:...|.:.:       ..||..:|.|
Human     4 IHPTSCCSYDTQRNPRKQSPGPRCLSGPIQLYQEPLRTKFSSISEGSRIGENLGWPDLIMEPDDF 68

  Fly    66 --------EWDINDAIVPHVPDQEFDEFNEWSDGHVRHIYSLHNEEAKKHISGWAMRNTNNHNVN 122
                    .|||||..:|. ..::.|.|.||.|.:.:||||..::.|::|:|.||||||||||..
Human    69 DSEDKEILSWDINDVKLPQ-NVKKTDWFQEWPDSYAKHIYSSEDKNAQRHLSSWAMRNTNNHNSR 132

  Fly   123 ILKKSCLGVLVCSQHCTLPNGSKINLRPAICDKARRKQEGKACPNKSCRGGRLEIKPCRGHCGYP 187
            |||||||||:||.:.|....|.||.||||||||||:||:.|.|||  | .|.|::.|||||.|:|
Human   133 ILKKSCLGVVVCGRDCLAEEGRKIYLRPAICDKARQKQQRKRCPN--C-DGPLKLIPCRGHGGFP 194

  Fly   188 VTHFWRHSGNAIFFQAKGVHDHLRPDPKNSSVSKRAFGRVPLAGKSANGSVAKKSVIAGLVKQAK 252
            ||:||||.|..||||:||.|||.:|:.|..:.::||..:|..|..|.:.|:...:....|..:.:
Human   195 VTNFWRHDGRFIFFQSKGEHDHPKPETKLEAEARRAMKKVNTAPSSVSLSLKGSTETRSLPGETQ 259

  Fly   253 QQHSLISKVLKRPAVSNP---LAHTALDIYQYNACGKCAGYSHCTCSY-------LDDSTTA--- 304
            .|.||......:..|..|   ..|...:..|.|:...|..:|.   ||       |.|.|:.
Human   260 SQGSLPLTWSFQEGVQLPGSYSGHLIANTPQQNSLNDCFSFSK---SYGLGGITDLTDQTSTVDP 321

  Fly   305 ----RSHQLSQSSNYGTNS-WPLSGS-------ESSAPCETAANVFTVNHQHIT----YNYPIYH 353
                ...:||.|..|.:.. .|.|.|       :..|..:.||    :...|:.    .||| :.
Human   322 MKLYEKRKLSSSRTYSSGDLLPPSASGVYSDHGDLQAWSKNAA----LGRNHLADNCYSNYP-FP 381

  Fly   354 ATPAAATAAPSKSPSLPYACSISELAAYQQ-----------------SSSGNSFAMGVPVHGHTQ 401
            .|....:.:||::.|.|:         |||                 :.:||.:...|.|..::.
Human   382 LTSWPCSFSPSQNSSEPF---------YQQLPLEPPAAKTGCPPLWPNPAGNLYEEKVHVDFNSY 437

  Fly   402 CQAVAYDSSPQLATPEPEFINYSQIKH 428
            .|:.|| .|||   .:|....|:...|
Human   438 VQSPAY-HSPQ---EDPFLFTYASHPH 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gcm2	NP_609302.1	GCM	82..222	CDD:281598	81/139 (58%)
GCM1	XP_016866879.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145946
Domainoid	1	1.000	208	1.000	Domainoid score	I2859
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003094
OrthoInspector	1	1.000	-	-		mtm8555
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12414
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4583
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.970