DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4382 and Ces2j

DIOPT Version :9

Sequence 1:	NP_609301.2	Gene:	CG4382 / 34279	FlyBaseID:	FBgn0032132	Length:	580	Species:	Drosophila melanogaster
Sequence 2:	XP_038953911.1	Gene:	Ces2j / 685645	RGDID:	1591368	Length:	576	Species:	Rattus norvegicus

Alignment Length:	608	Identity:	167/608 - (27%)
Similarity:	253/608 - (41%)	Gaps:	123/608 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 GQNSDEDLSKAIPDEEDPIGSN---------KELSDLVITTALGKIRGT---ILPSQSGRNFYAF 69
            |...:.:..|.|||      ||         ::.:..:..|..|::||:   :..::||  .:.|
  Rat    22 GLRRERERKKGIPD------SNLHSFLTEQGQDSASPIRNTHTGQVRGSFVHVKDTKSG--IHTF 78

  Fly    70 RGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCPQLGLVSGD-----------VSEDCLRV 123
            .|||:|||||..|||.|||..|.|....|||.....|.|..:::.:           :|||||.:
  Rat    79 LGIPFAKPPVGPLRFAPPEDPEPWSGVRDATSQPAMCLQTAMMNLEGMKETELTKLPMSEDCLYL 143

  Fly   124 NIYTKELPSESQPNVRRPVIVFIHPGGFYSLSGQSKNFAGPQYFMNRRLVLVTFNYRLGSLGFLA 188
            |||   :|:.:..:...||:|:||.||.  :.|.:.............:|:|:..||||.|||.:
  Rat   144 NIY---VPAHAHEDSNLPVMVWIHGGGL--VGGSASMNDASTLAATEEIVIVSIQYRLGVLGFFS 203

  Fly   189 TGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPSSITLLGYGAGAMAVTLHMVSPMSRGLFHKAI 253
            ||.:.|.||.|..||:..||||:.:|:.|||:..|:|:.|..||..:|:.|:|||||:||||:||
  Rat   204 TGDQHARGNWGYLDQMAALRWVQQNIAYFGGNRDSVTIFGVSAGGTSVSSHVVSPMSKGLFHRAI 268

  Fly   254 VMSGAVTGQWSLPDHQMDVATKQATLLHCHTENVTEMMDCLKGKHYLEF--ANTLPKMFEFDRNN 316
            :.||.......:.|....|....|.|..|...:...::.||:.|...|.  .|.:.||.
  Rat   269 MQSGVALLPGLISDTSEVVYKTVANLSGCEASDSEALIRCLRAKSKQEILAINQVFKMI------ 327

  Fly   317 PLILWKPVIEPDFGQERFLVEEPIRSYQNDDFMKVPIITGMTKDEFVGPALSILQSPTLLSALNE 381
                      |.....:||.:.|.....:.||..||.|.|:..|| .|..:     ||:|.
  Rat   328 ----------PGVVDGKFLPKHPQELLASKDFHPVPSIIGVNTDE-CGWGV-----PTILG---- 372

  Fly   382 NFESLAPVFFMYNTSDARACNISQE---------LRNHYFPDKLIDA--------NRSLEALSNL 429
                   ::.:.|       ||::|         ......|.:.||.        ....|.|...
  Rat   373 -------LYHIIN-------NITRETLPAALKIAAAQMMLPPECIDLIMEEYMGDTEDAETLQAQ 423

  Fly   430 YSDALTGFGIHRFV-------HLAARSTKVYYYRFSYQGARSHI-----YYPEDAPYGVVHHDDL 482
            :.:.|..|   .||       |.......||:|.|  |...|.|     :||:     ..|.||.
  Rat   424 FKEMLGDF---IFVIPALQVAHFQRSQAPVYFYEF--QHLLSFIKQVRPFYPK-----ADHGDDT 478

  Fly   483 MYLFVEPSISRMFTEDDDEFRMVDIMVRMFSAFAYKGDPNKPTDLALRDIRWRPFSFKKRYYLDI 547
            :::|........|...::|..:...:::.::.||..|:||.      .|:...|.......||.:
  Rat   479 VFVFGSYFWGMTFDLTEEEELLKRRVMKYWANFARTGNPNG------EDLPHWPVLDHDEQYLQL 537

  Fly   548 GKHITLEENLNAENYEIWKRLFP 570
            .....:...|.|...:.|.:..|
  Rat   538 NSQPAVGRALKARRLQFWTKTLP 560

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	41..565	CDD:278561	158/568 (28%)
Ces2j	XP_038953911.1	COesterase	50..555	CDD:395084	158/567 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336347
Domainoid	1	1.000	232	1.000	Domainoid score	I2325
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	232	1.000	Inparanoid score	I3341
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.890