Protein Alignment CG4382 and Ces2b

DIOPT Version :10

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_001094469.1
• Gene: Ces2b / 679149
• RGDID: 1591847
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 596
• Identity: 168/596 - (28%)
• Similarity: 262/596 - (43%)
• Gaps: 97/596 - (16%)

  Fly     6 GFVLLLCGLASGQNSDEDLSKAIPDEEDPIGSNKELSDLVITTALGKIRGT---ILPSQSGRNFY 67
            |.:|||..: .||:|.|                   |..:..|.:|::||.   :..:::|  .:
  Rat    16 GLLLLLIHV-QGQHSPE-------------------SSPIRNTHIGQVRGKLDHVKDTKAG--VH 58

  Fly    68 AFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCPQ-LGLVSGD-------------VSE 118
            .|.|||:|||||..|||.|||..|.|....|.|.....|.| |.:::.:             :||
  Rat    59 TFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTSQPAMCLQNLDVINAEGLKEMKLKLPPVSMSE 123

  Fly   119 DCLRVNIYTKELPSESQPNVRRPVIVFIHPGGFYSLSGQSKNFAGPQYFMNRRLVLVTFNYRLGS 183
            |||.:|||.   |:.:......||:|:||.||.  ::|.:..:.|....:|..||:||..||||.
  Rat   124 DCLYLNIYA---PAHAHEGSNLPVMVWIHGGGL--MTGMASMYDGSLLTVNEDLVVVTIQYRLGV 183

  Fly   184 LGFLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPSSITLLGYGAGAMAVTLHMVSPMSRGL 248
            |||.:||...|.||.|..|||..||||:.:|:.|||:|..:|:.|..||...|:.|:|||||:||
  Rat   184 LGFFSTGDEHARGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTCVSTHVVSPMSQGL 248

  Fly   249 FHKAIVMSGAVTGQWSLPDHQMDVATKQATLLHCHTENVTEMMDCLKGKHYLEFANTLPKMFEFD 313
            ||.||:.||.....:.:.|.....:|..|.:..|...:...::.||:.|...|....
  Rat   249 FHGAIMESGVALLPYLIADTSEMFSTMVAKVSGCEAMDSEALVHCLRAKSEAEILAI-------- 305

  Fly   314 RNNPLILWKPVIEPDFGQERFLVEEPIRSYQNDDFMKVPIITGMTKDEFVGPALSILQSPTLLSA 378
              |.::...|.:.    ...||...|.....::||..||.|.|:..||:......::.:..::..
  Rat   306 --NKVVQMVPAVV----DGEFLPRHPKELLASEDFRPVPSIIGVNNDEYGWTIPLVMGTTQMIKE 364

  Fly   379 LN-ENFESL-----APVFFMYNTSDARACNISQELRNHYFPDKLIDANRSLEA-LSNLYSDALTG 436
            |: ||.:::     |.:......||.        |...|..|  |:..::|:| .:.|..|.:..
  Rat   365 LSRENLQAILKKTTAQLMLPLECSDL--------LMEEYMGD--IEDPKTLQAQFTELMEDFMFV 419

  Fly   437 FGIHRFVHLAARSTKVYYYRFSYQGARSHIYYPED--APYGVVHHDDLM-----YLFVEPSISRM 494
            ....:..|.......||:|.|.:|     |.:.:|  .|:....|.|.:     |.|.:  :...
  Rat   420 IPALQVAHFQCSHAPVYFYEFQHQ-----ITFLKDIRPPHVKADHGDEIPFVFGYFFWD--MKTD 477

  Fly   495 FTEDDDEFRMVDIMVRMFSAFAYKGDPNKPTDLALRDIRWRPFSFKKRYYLDIGKHITLEENLNA 559
            |||  :|..:...|::.::.||..|:||.      ..:.:.|.....:.||.:.....:...|.|
  Rat   478 FTE--EEKLLSRRMMKYWANFARHGNPNS------EGLSYWPVMDHDQQYLQLDTQPAVGRALKA 534

  Fly   560 ENYEIWKRLFP 570
            ...:.|.:..|
  Rat   535 RRLQFWTKTLP 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	42..565	CDD:395084	158/553 (29%)
Ces2b	NP_001094469.1	COesterase	32..540	CDD:395084	158/553 (29%)