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Protein Alignment CG4382 and BCHE

DIOPT Version :9

Sequence 1:	NP_609301.2	Gene:	CG4382 / 34279	FlyBaseID:	FBgn0032132	Length:	580	Species:	Drosophila melanogaster
Sequence 2:	NP_000046.1	Gene:	BCHE / 590	HGNCID:	983	Length:	602	Species:	Homo sapiens

Alignment Length:	606	Identity:	179/606 - (29%)
Similarity:	281/606 - (46%)	Gaps:	99/606 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RLCGFVLLLCGLASGQNSDEDLSKAIPDEEDPIGSNKELSDLVITTALGKIRGTILPSQSGRNFY 67
            |...:.||||.|. |::..||                   |::|.|..||:||..| :..|....
Human    11 RFLFWFLLLCMLI-GKSHTED-------------------DIIIATKNGKVRGMNL-TVFGGTVT 54

  Fly    68 AFRGIPYAKPPVDRLRFQPPEPVEQWFD-------------TLDATFDGPKCPQLGLVSGDVSED 119
            ||.|||||:||:.||||:.|:.:.:|.|             .:|.:|.|....::...:.|:|||
Human    55 AFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSED 119

  Fly   120 CLRVNIYTKELPSESQPNVRRPVIVFIHPGGFYSLSGQSKNFAGPQYFMNRRLVLVTFNYRLGSL 184
            ||.:|::   :|:....|.  .|:::|:.|||.:.:.....:.|.......|:::|:.|||:|:|
Human   120 CLYLNVW---IPAPKPKNA--TVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGAL 179

  Fly   185 GFLA-TGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPSSITLLGYGAGAMAVTLHMVSPMSRGL 248
            |||| .|..||||||||.||...|:||:.:|:.|||:|.|:||.|..|||.:|:||::||.|..|
Human   180 GFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSL 244

  Fly   249 FHKAIVMSGAVTGQWSLPD--HQMDVATKQATLLHCHTENVTEMMDCLKGKHYLEFANTLPKMFE 311
            |.:||:.||:....|::..  ...:.....|.|..|..||.||::.||:.|...|.  .|.:.|.
Human   245 FTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEI--LLNEAFV 307

  Fly   312 FDRNNPL-ILWKPVIEPDFGQERFLVEEPIRSYQNDDFMKVPIITGMTKDEFVGPALSILQSPTL 375
            .....|| :.:.|.::.|     ||.:.|....:...|.|..|:.|:.|||  |.|..:..:|..
Human   308 VPYGTPLSVNFGPTVDGD-----FLTDMPDILLELGQFKKTQILVGVNKDE--GTAFLVYGAPGF 365

  Fly   376 LSALN-----ENFESLAPVFFMYNTSDARACNISQELRNHYFPDKLIDANRS---LEALSNLYSD 432
            ....|     :.|:....:||...:...:     :.:..||  ...:|..|.   .|||.::..|
Human   366 SKDNNSIITRKEFQEGLKIFFPGVSEFGK-----ESILFHY--TDWVDDQRPENYREALGDVVGD 423

  Fly   433 ALTGFGIHRFVHLAARSTKVYYYRFSYQGARSHIYYPE----DAPY----GVVHHDDLMYLFVEP 489
                   :.|:..|...||    :||..|..:..||.|    ..|:    ||:|..::.::|..|
Human   424 -------YNFICPALEFTK----KFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLP 477

  Fly   490 SISRMFTEDDDEFRMVDIM----VRMFSAFAYKGDPNKPTDLALRDIRWRPFSFKKRYYLDIGKH 550
            ...|     |:..:..:|:    |:.::.||..|:||:..:   ....|..|...::.||.:...
Human   478 LERR-----DNYTKAEEILSRSIVKRWANFAKYGNPNETQN---NSTSWPVFKSTEQKYLTLNTE 534

  Fly   551 IT-LEENLNAENYEIWKRLFP 570
            .| :...|.|:....|...||
Human   535 STRIMTKLRAQQCRFWTSFFP 555

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.