Protein Alignment CG4382 and NLGN4X

DIOPT Version :9

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: XP_005274621.1
• Gene: NLGN4X / 57502
• HGNCID: 14287
• Length: 836
• Species: Homo sapiens
• Alignment Length: 622
• Identity: 167/622 - (26%)
• Similarity: 262/622 - (42%)
• Gaps: 149/622 - (23%)

  Fly    45 VITTALGKIRG--TILPSQSGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCP 107
            |:.|..|||||  |.||::.......:.|:|||.||....|||||||...|....:.|.....||
Human    47 VVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCP 111

  Fly   108 Q----------------------LGLVSGDVSEDCLRVNIYTKELPSES---------------- 134
            |                      |.....|.:||||.:|||   :|:|.
Human   112 QHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIY---VPTEDGANTKKNADDITSNDR 173

  Fly   135 -------QPNVRRPVIVFIHPGGFYSLSGQSKNFAGPQYFMNRRLVLVTFNYRLGSLGFLATGTR 192
                   ..|.::||:|:|| ||.| :.|......|........::::|.|||||.||||:||.:
Human   174 GEDEDIHDQNSKKPVMVYIH-GGSY-MEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQ 236

  Fly   193 EAPGNMGLKDQVQLLRWVKLHISRFGGDPSSITLLGYGAGAMAVTLHMVSPMSRGLFHKAIVMSG 257
            .|.||.||.||:|.|||::.::..|||||..:|:.|.||||..|:|..:|..|.|||.|||:.||
Human   237 AAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSG 301

  Fly   258 AVTGQWSLPDHQMDVATKQATLLHCHTENVTEMMDCLKGKHYLEF--ANTLPKMFEFDRNNPLIL 320
            .....|::...........|..:.|:..:.|:|::||:.|:|.|.  ....|..:.       |.
Human   302 TALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATYH-------IA 359

  Fly   321 WKPVIEPDFGQERFLVEEPIRSYQNDDFMKVPIITGMTKDEFVGPALSILQSPTLLSALNENFES 385
            :.|||:.|     .:.::|....:..:|:...|:.|:.:.|.:          ..:..:.:|.:.
Human   360 FGPVIDGD-----VIPDDPQILMEQGEFLNYDIMLGVNQGEGL----------KFVDGIVDNEDG 409

  Fly   386 LAPVFFMYNTSDARACNISQELRNHYFPDKLI------DANRSLEALSNLYSD------------ 432
            :.|..|.::.|:              |.|.|.      |..|  |.:..:|:|
Human   410 VTPNDFDFSVSN--------------FVDNLYGYPEGKDTLR--ETIKFMYTDWADKENPETRRK 458

  Fly   433 ---ALTGFGIHRFVHLAARS--------TKVYYYRFSYQGARSHI--YYPEDAPYGVVHHDDLMY 484
               ||  |..|::|..|..:        :..|:|.| |...:|.:  .:.:.|     |.|::.|
Human   459 TLVAL--FTDHQWVAPAVATADLHAQYGSPTYFYAF-YHHCQSEMKPSWADSA-----HGDEVPY 515

  Fly   485 LFVEPSI------SRMFTEDDDEFRMVDIMVRMFSAFAYKGDPNKPTDL----------ALRDIR 533
            :|..|.|      |..|:::|  ..:..:::..::.||..||||:|...          ...::.
Human   516 VFGIPMIGPTELFSCNFSKND--VMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVA 578

  Fly   534 WRPFSFKKRYYLDIGKHITLEENLNAENYEIWKRLFP 570
            |..::.|.:.||.||....:.::..|.....|..|.|
Human   579 WSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVP 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	41..565	CDD:278561	164/615 (27%)
NLGN4X	XP_005274621.1	COesterase	42..610	CDD:278561	164/615 (27%)
		Aes	<179..>286	CDD:223730	47/108 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165142843
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740