Protein Alignment CG4382 and nlgn2a

DIOPT Version :10

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: XP_009301340.1
• Gene: nlgn2a / 556158
• ZFINID: ZDB-GENE-090918-2
• Length: 828
• Species: Danio rerio
• Alignment Length: 647
• Identity: 183/647 - (28%)
• Similarity: 273/647 - (42%)
• Gaps: 157/647 - (24%)

  Fly    14 LASGQNSDEDLSKAIPDEEDPIGSNKELSDLVITTALGKIRG-------TIL-PSQSGRNFYAFR 70
            |||.|..|       |..:.|          .:||..||:||       .|| |.:.      :.
Zfish    34 LASCQRID-------PGTKYP----------TVTTNYGKLRGIKKELNNEILGPVEQ------YL 75

  Fly    71 GIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCPQ--LGLV-----------SGDV------ 116
            |:|||..|:...||||||....|.:..:||...|.|||  .|::           |.||
Zfish    76 GVPYATAPIGDRRFQPPEAPGSWQEVRNATQFAPVCPQNVHGVLPEIMLPVWFTDSLDVAATYIQ 140

  Fly   117 --SEDCLRVNIYTKELPSESQP----------------NVR----RPVIVFIHPGGFYSLSGQSK 159
              |||||.:|:|   :|:|..|                ::|    :||::||| ||.| :.|...
Zfish   141 NQSEDCLYLNVY---VPTEDGPLTKKHDESTLNRPRDEDIRDRRKKPVMLFIH-GGSY-MEGTGN 200

  Fly   160 NFAGPQYFMNRRLVLVTFNYRLGSLGFLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPSSI 224
            .|..........:::||.|||||.||||:||.:.|.||.||.||:|.|||:..:|..|||||..|
Zfish   201 MFDASVLAAYGNVIVVTMNYRLGVLGFLSTGDQSAKGNYGLLDQIQALRWLNENIGHFGGDPERI 265

  Fly   225 TLLGYGAGAMAVTLHMVSPMSRGLFHKAIVMSGAVTGQWSLPDHQMDVATKQATLLHCHTENVTE 289
            |:.|.||||..|.|.::|..|.|||.:||..||:....||:....:......|..:.|......:
Zfish   266 TIFGSGAGASCVNLLILSHHSEGLFQRAIAQSGSAISSWSISYQPLKYTKILARKVGCTYGETAD 330

  Fly   290 MMDCLKGKHYLEFA--NTLPKMFEFDRNNPLILWKPVIEPDFGQERFLVEEPIRSYQNDDFMKVP 352
            ::|||:.|::.|..  :..|..:.       |.:.||::.|     .:.::|....|..:|:...
Zfish   331 LVDCLRRKNFRELVDQDIQPARYH-------IAFGPVMDGD-----VVPDDPEILMQQGEFLNYD 383

  Fly   353 IITGMTKDEFVGPALSILQSPTLLSALNENFESLAPVFFMYNTSDARACNISQELRNHYFPDKLI 417
            ::.|:.:    |..|..:.     ....|:.|.::...|.|        .||..:.|.|...|..
Zfish   384 LLIGVNQ----GEGLKFVD-----DGGTESEEGISAAAFDY--------TISNFVDNLYGYPKGK 431

  Fly   418 DANRSLEALSNLYSD-------------ALTGFGIHRFVHLAARSTK--------VYYYRFSYQG 461
            |..|  |.:..:|:|             .|..|..|::|..|..:.|        ||:|.| |..
Zfish   432 DILR--ETIKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAIATAKLHADYQSPVYFYTF-YHH 493

  Fly   462 ARSHIYYPE--DAPYGVVHHDDLMYLFVEPSISRM------FTEDDDEFRMVDIMVRMFSAFAYK 518
            .::.. .||  ||.:|    |::.|:|..|.|...      |:::|  ..:..:::..::.||..
Zfish   494 CQTET-RPEWADAAHG----DEIPYVFGVPMIGATDLFPCNFSKND--IMLSAVVMTYWTNFAKT 551

  Fly   519 GDPNKPTDL----------ALRDIRWRPFSFKKRYYLDIGKHITLEENLNAENYEIWKRLFP 570
            ||||.|...          ...::.|..|:.|.:.||.||....:.:|..|.....|..|.|
Zfish   552 GDPNLPVPQDTKFIHTKPNRFEEVIWTKFNSKDKQYLHIGLKPRIRDNYRANKVAFWLELVP 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	42..565	CDD:395084	173/612 (28%)
nlgn2a	XP_009301340.1	COesterase	47..608	CDD:395084	174/620 (28%)