Protein Alignment CG4382 and Nlg1

DIOPT Version :9

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Alignment Length: 641
• Identity: 153/641 - (23%)
• Similarity: 254/641 - (39%)
• Gaps: 134/641 - (20%)

  Fly    14 LASGQNSDE---------DLSKAIPDEEDPIGSNKELSDLVITTALGKIRGTILPSQ--SG-RNF 66
            ||:.:.|.|         :....:||:   :...:|     |....|::.|.....|  || |..
  Fly   125 LATDEGSSEHEPSTTHHPERRHVVPDK---LQYTQE-----IQVKQGRLMGITRRFQVTSGLRQV 181

  Fly    67 YAFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCPQ----------------------- 108
            ..|.|:|||:.|....||.||.....|.....|....|.|||
  Fly   182 DQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVCPQKLPDLSPHGSENMSRARHKHLSR 246

  Fly   109 -LGLVSGDVSEDCLRVNIYTKELPSESQPNVRRPVIVFIHPGGFYSLSGQSKNFAGPQYFMNRRL 172
             |..:..: |||||.:|:|......:|.|. :..|:|::|...|...||..  :.|........:
  Fly   247 LLPYLRTE-SEDCLYLNLYVPHEEPQSTPK-QYAVLVYLHGESFEWNSGNP--YDGSVLSSYGEV 307

  Fly   173 VLVTFNYRLGSLGFLATG-TREAPGNMGLKDQVQLLRWVKLHISRFGGDPSSITLLGYGAGAMAV 236
            ::||.|||||.||||... ......|..|.||:..|.|:|.:|..||||.|.:||:|:..||..|
  Fly   308 IVVTVNYRLGVLGFLRPSIDAHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACV 372

  Fly   237 TLHMVSPMSRGLFHKAIVMSGAVTGQWSLPDHQMDVATKQATLLHC----HTENVTE--MMDCLK 295
            ...||||::.||||:||:|||:....|:..:..:.:..:.|..|.|    |.|...:  ::|||:
  Fly   373 NYLMVSPVASGLFHRAILMSGSAMSDWAASNQSLQLTMQIAHALECPLNEHVEAEDDDVLLDCLR 437

  Fly   296 GKHYLEFANTLPKMFEFDRN-NPLILWKPVIEPDFGQERFLVEEP--IRSYQNDDFMKVPIITGM 357
            .:.|.:..:....:.:|..: .|::           ....:..:|  :..:..:.|.:..::.|:
  Fly   438 HRRYQDILHIPTALTQFSTSLGPIV-----------DGHVIPNQPYKVMGHYTEHFSRYDLLFGI 491

  Fly   358 TKDEFVGPALSILQSPTLLSALNENFESLAPVFFMYNTSDARACNISQELRNHYFPDKLIDANRS 422
            |:.|    :...|.:..|...|.||.......|:|.:..|.|             ||..:.|  :
  Fly   492 TESE----SYHTLAALALEEGLRENERDNLLRFYMQSRFDIR-------------PDLALAA--T 537

  Fly   423 LEALSNLYSDALTGFGI-HRFVHL-------------------AARSTKVYYYRFSYQGARSHIY 467
            |:...::|::.:....: ||.|.|                   |..:.:.|.|.|.:..|
  Fly   538 LKKYQDMYNNPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHADVNRRNYMYVFGHNSA----- 597

  Fly   468 YPEDAPYGVVHH----DDLMYLFVEP-SISRMFTEDD---DEFRMVDIMVRMFSAFAYKGDPNKP 524
               ..|:..:.|    ::|.::|..| :.:..|...:   .|..:.:.::..::.|...|:|..|
  Fly   598 ---TGPFAHLPHSIMGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAP 659

  Fly   525 ------TDLALR----DIRWRPFSFKKRYYLDIGKHITLEENLNAENYEIWKRLFP 570
                  ...||.    |:.|..|:.:.:.||:||...|:...........|.:..|
  Fly   660 WKGIFINSHALEWDRYDLDWPEFNRRAQAYLNIGIPPTVGYKYRQIYMNFWNKELP 715

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	41..565	CDD:278561	144/598 (24%)
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	145/603 (24%)
		Aes	<263..>408	CDD:223730	54/147 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.810