DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4382 and CG10339

DIOPT Version :9

Sequence 1:	NP_609301.2	Gene:	CG4382 / 34279	FlyBaseID:	FBgn0032132	Length:	580	Species:	Drosophila melanogaster
Sequence 2:	NP_611881.1	Gene:	CG10339 / 37854	FlyBaseID:	FBgn0034972	Length:	603	Species:	Drosophila melanogaster

Alignment Length:	568	Identity:	145/568 - (25%)
Similarity:	247/568 - (43%)	Gaps:	90/568 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 GKIRGTILPSQSGRNFYAFRGIPYAKPPVDRLRFQPPE-PVEQWFDTLDATFDGPKC-----PQL 109
            |.|.||.|.....:|..|:.||.||    ...|||||: .:..|....:||...|.|     |.:
  Fly    40 GVISGTYLKMFRTQNIKAYLGIRYA----HARRFQPPDIELTPWKGIFNATVFQPDCWQNAMPSV 100

  Fly   110 G--------LVSGDVS---------EDCLRVNIYTKELPSESQPNVR-RPVIVFIHPGGFYSLSG 156
            |        ::..|.|         |:||.:|::.    .:..|.:. ..|:|:||.|.|  .:|
  Fly   101 GKETEQILKIIQSDSSAQDAERKYEENCLYLNVFV----PDGLPEINGYAVVVWIHSGDF--STG 159

  Fly   157 QSKNFAGPQYFMNRRLVLVTFNYRLGSLGFLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDP 221
            ...:....|....:::::|||:|||...||..|...||.||.||.||...|.|||.:|:.||||.
  Fly   160 SPADVEPFQLVFKQKVIVVTFSYRLNIFGFFTTDDGEAQGNYGLMDQSAALYWVKKNINFFGGDS 224

  Fly   222 SSITLLGYGAGAMAVTLHMVS-PMSRGLFHKAIVMSGAVTGQWSLPDHQMDVATKQATLLHCHTE 285
            :.|||:|:.|||::|.|||.| ..|:|.|||||:|||.......:|........:.::...|...
  Fly   225 NRITLMGHDAGAVSVALHMTSGEWSKGGFHKAIIMSGNPLSTVKMPYEYEGSLDQVSSTFACPRR 289

  Fly   286 NVTEMMDCLKGKHYLEFANTLPKMFEFDRNNPLILWKPVIEPDFGQER----FLVEEPIRSYQND 346
            ..:..:.|||.......:..||:          :.|.||:  |||...    |:..:|...::..
  Fly   290 PTSMFIQCLKRIDAKRLSENLPQ----------VSWGPVV--DFGLSNTSYPFIENQPEILFKKG 342

  Fly   347 DFMKVPIITGMTKDEFVGPALSILQSPTLLSALNENFES-LAPVFFMYNTSDARACNISQELRNH 410
            .:.:||:|.|:|..|.|            |:...:|.:: ::|.......:|....::.:.:||:
  Fly   343 SYHRVPVIIGVTDMEEV------------LTLFKDNLDTDISPSDLEGFYTDIAVTDMHKLVRNY 395

  Fly   411 ----------------YFPDKLIDANRSLEALSNLYSDALTGFGIHRFVHLAARSTKVYYYRFSY 459
                            |..|...||.::.:.:.:.:::......:..|..|.:..::||.|.|..
  Fly   396 EWCSNYELISDAINFMYANDSDTDAKKANKHIISAHTEKFYITPMQTFADLISNDSQVYSYLFRM 460

  Fly   460 QGARSHIYYPEDAP--YGVVHHDDLMYLFVEPSISRMFTEDDDEFRMVDIMVRMFSAFAYKGDPN 522
            : .||.:   :|.|  ..|..:.|.::::..|.::........:.::.||::.:::.||...:|.
  Fly   461 R-PRSVL---QDLPSWISVPKYFDQIFVWGNPYMTNSVDWKSTDKKIADIIMTLWANFAKTSNPT 521

  Fly   523 KPTDLALRDIRWRPFSFKKRYYLDIGKHITLEENLNAENYEIWKRLFP 570
            |....    ::|...:......|.|.:....:..||.:....|:.|:|
  Fly   522 KSNVY----VKWNAMTPNNDSVLLIDESFNTDNLLNNQRINFWRSLYP 565

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	41..565	CDD:278561	142/561 (25%)
CG10339	NP_611881.1	COesterase	30..560	CDD:278561	142/561 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
	4	3.810