DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4382 and gas

DIOPT Version :9

Sequence 1:	NP_609301.2	Gene:	CG4382 / 34279	FlyBaseID:	FBgn0032132	Length:	580	Species:	Drosophila melanogaster
Sequence 2:	NP_611678.1	Gene:	gas / 37572	FlyBaseID:	FBgn0034736	Length:	566	Species:	Drosophila melanogaster

Alignment Length:	543	Identity:	171/543 - (31%)
Similarity:	258/543 - (47%)	Gaps:	88/543 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 GSNKELSDLVITTALGKIRG----TILPSQSGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDT 96
            |..|||:     |..|:::|    |:   ..|..:|:|.|||:|:|||..|||:.|:|...|...
  Fly    30 GQTKELA-----TKYGQLKGQQRRTL---YDGEPYYSFEGIPFAQPPVGELRFRAPQPPSSWQGV 86

  Fly    97 LDATFDGPKCPQLGLV--SGDVSEDCLRVNIYTKELPSESQPNVRRPVIVFIHPGGFYSLSGQSK 159
            .|.|:...|..|...:  :.:.|||||.:|:|.|.|.|...    .||:|:|..||| .:.|.|:
  Fly    87 RDCTYAREKPMQRNSITNAAEGSEDCLYLNVYAKRLESPKP----LPVMVWIFGGGF-QVGGASR 146

  Fly   160 NFAGPQYFMNRRLVLVTFNYRLGSLGFLATGTRE--APGNMGLKDQVQLLRWVKLHISRFGGDPS 222
            ...||.|||...::|||.|||:|.||||:...:|  .|||.|||||:|.|||||.:|:.|.|||.
  Fly   147 ELYGPDYFMKHDILLVTINYRVGVLGFLSLKDKELKIPGNAGLKDQIQALRWVKENIASFNGDPE 211

  Fly   223 SITLLGYGAGAMAVTLHMVSPMSRGLFHKAIVMSGAVTGQWSL-PDHQMDVATKQATLLHCHTEN 286
            |||:.|..||..:..:.|.:..:|||||:|||.||:....|:. ||.:......:......:.|:
  Fly   212 SITVFGESAGGASTHILMQTEQARGLFHRAIVQSGSALCAWATQPDRKWPQRLGKELGYAGNLES 276

  Fly   287 VTEMMDCLKGKHYLEFANTLP--KMFEF---------DRNNPLILWKPVIEPDFGQERFLVEEPI 340
            ..|:         |||...:|  |:.::         .|:..::.:.|||||..|.:..:.:...
  Fly   277 EKEL---------LEFFQQIPASKLAQYCNSIVTQEEQRDYEILAFAPVIEPYVGDDCVIPKSQQ 332

  Fly   341 RSYQNDDFMKVPIITGMTKDEFVGPALSILQSPT-LLSALNENFESLAPVFFMYNTSDARACNIS 404
            ....:.....:|:|.|.|..|.:....:.|..|. :|||    ||::.|..............:.
  Fly   333 EQLSSAWGNSIPMIIGGTSFEGLFSYRTTLDDPLYMLSA----FEAIIPKQVRDAIDKEELAEMV 393

  Fly   405 QELRNHYF--PDKLIDANRSLEALSNLYSDALTGF--GIHR--FVHLA-ARSTKVYYYRFSYQGA 462
            :.|:..||  ||:     .|:|....|:..::..|  .|||  ...|| |.:...|.|||..
  Fly   394 RRLKKSYFDDPDR-----ASMELYECLHILSIKNFWHDIHRTLLARLAYATNLPTYLYRFDM--- 450

  Fly   463 RSHIYYPEDAPY--------------GVVHHDDLMYLFVEPSISRMFTEDDDEFRMVDIMVRMFS 513
                    |:|:              ||.|.||:.|:|. ..:|....::..|:|.::.:|.|::
  Fly   451 --------DSPHFNHYRILKCGKKVRGVCHADDISYMFY-GILSSKLDKNSPEYRTIERLVGMWT 506

  Fly   514 AFAYKGDPNKPTDLALRDIRWRP 536
            :||..||||..   .:..::|.|
  Fly   507 SFATTGDPNCE---IIAPVKWDP 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	41..565	CDD:278561	168/538 (31%)
gas	NP_611678.1	COesterase	28..534	CDD:278561	171/543 (31%)
gas	NP_611678.1	Aes	<117..>222	CDD:223730	54/109 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467394
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	99	1.000	Inparanoid score	I1664
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
	9	8.800