DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4382 and CG12869

DIOPT Version :9

Sequence 1:	NP_609301.2	Gene:	CG4382 / 34279	FlyBaseID:	FBgn0032132	Length:	580	Species:	Drosophila melanogaster
Sequence 2:	NP_001369085.1	Gene:	CG12869 / 36616	FlyBaseID:	FBgn0033943	Length:	839	Species:	Drosophila melanogaster

Alignment Length:	573	Identity:	146/573 - (25%)
Similarity:	234/573 - (40%)	Gaps:	122/573 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 ILPSQSGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCPQL----------GL 111
            :.|..:....|||.|||||:.|::.|||.|.:|...:..||.||...|.||||          |.
  Fly    43 VFPDGTRGAVYAFLGIPYAQAPINELRFAPAKPSSSFNRTLQATTMQPLCPQLANTIYDESSDGS 107

  Fly   112 VSGDVS--EDCLRVNIYTKELPSESQPNVRRPVIVFIHPGGFYSLSGQSKNFAGPQYFMN----- 169
            :...||  ||||.:||:|   |.......:.|::|.:        :|:...:..|:..:|
  Fly   108 MPRSVSTDEDCLYLNIWT---PESGMRYGKLPIVVIV--------TGEEFAYDWPRNRINGLDLA 161

  Fly   170 -RRLVLVTFNYRLGSLGFLATGT--REAPGNMGLKDQVQLLRWVKLHISRFGGDPSSITLLGYGA 231
             ..:|:|:..||....|:|:.|.  |..|||.||.|....|||::.:...|||:|..|||||:|:
  Fly   162 GEGIVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQMALRWIRRNADAFGGNPDHITLLGHGS 226

  Fly   232 G----AMAVTLHMVSP------MSRGLFHKAIVMSGAVTGQWSLPDHQ-MDVATKQATL--LHCH 283
            |    |:..||...|.      ||.|...:|:       ||    :|| ..|.|.|..:  |.|.
  Fly   227 GGAPLALVATLEDSSQVKQLVLMSPGPIMRAL-------GQ----NHQKWIVETGQVLVQKLGCQ 280

  Fly   284 TENV--TEMMDCLKGKHYLEFANTLPKMFEFDRNNPLILWKPVIEPDFGQERFLVEEPIRSYQND 346
            .|..  .::|.||:.|...:.......::.....:..:   .||.|    |...:|:.:|:
  Fly   281 FEEAQRRQLMGCLRRKSREDLLRAYESVYNHGNGSSQL---GVILP----EGLPLEQRLRN---- 334

  Fly   347 DFMKV--PIITGMTKDE--FVGP-----------ALSILQSPTLLSALNENFESLAPVFFMYNTS 396
               |.  |::.|:|.:|  |:..           ||....:.|||..:....||:..     .:|
  Fly   335 ---KTLPPVLLGITSNEGAFLQDYWLDVAREGQVALHKYINHTLLPNVMRALESVGE-----ESS 391

  Fly   397 DARACNISQELRNHYFPDKLIDANRSLEALSNLYSDALTGFGIHRFVHLAARSTKVYYYRFSY-- 459
            ...|.     :|..||..|....:..|..:..|.|::|......|.:.| ...|..|.|.|.:
  Fly   392 TQLAA-----IRWRYFNGKGEGVSHLLAGMQRLLSESLYELPYSRILEL-LNGTTSYAYVFDHSH 450

  Fly   460 ----QGARSHIYYPEDAPYGVVHHDDLMYLFVEPSI-----SRMFTEDDDEFRMVDIMVRMFSAF 515
                :|.|:        .:|...|...:.|.:.||:     .|.|:.::::     :..::..||
  Fly   451 SMDMRGRRN--------LFGGASHSSDLPLLLGPSLFQQIARRRFSGEEEQ-----LCRKIRGAF 502

  Fly   516 AYKGDPNKPTDLALRDIRWRPFSFKKRYYLDIGKHITLEENLNAENYEIWKRL 568
            |.......||...:.| .|.|::.:..:...:|:.....:..:.:..|:.|.|
  Fly   503 ANFIKNGNPTPGRIYD-GWLPYNKENPFVYSLGEQAKTPQTGSVDEAEVDKLL 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	41..565	CDD:278561	144/568 (25%)
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	143/558 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910