DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4382 and cel.1

DIOPT Version :9

Sequence 1:	NP_609301.2	Gene:	CG4382 / 34279	FlyBaseID:	FBgn0032132	Length:	580	Species:	Drosophila melanogaster
Sequence 2:	NP_955901.2	Gene:	cel.1 / 322481	ZFINID:	ZDB-GENE-030131-1201	Length:	550	Species:	Danio rerio

Alignment Length:	574	Identity:	160/574 - (27%)
Similarity:	249/574 - (43%)	Gaps:	91/574 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 LVITTALGKIRGTILPSQSG------------RNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDT 96
            |.:.||.|...|.:| ::.|            |....|:|||:|.||   .||:.|.....|...
Zfish    12 LFLGTAQGASLGAVL-TEGGMVQGKSRSVGLFRYMDTFKGIPFAAPP---KRFEKPVAHPGWEGV 72

  Fly    97 LDATFDGPKCPQLGLVSGDV--SEDCLRVNIYTKELPSESQPNVRRPVIVFIHPGGFYSLSGQSK 159
            |..|....:|.||.|::.||  |||||.:||:   :|.....:...||:|||:.|.|....||..
Zfish    73 LKTTDYRKRCLQLNLLATDVIGSEDCLYLNIW---VPQGRTVSSNLPVMVFIYGGAFLLGGGQGA 134

  Fly   160 NFA------GPQYFMNRRLVLVTFNYRLGSLGFLATGTREAPGNMGLKDQVQLLRWVKLHISRFG 218
            ||.      |.:......:::||||||:|:|||::||....|||.||.||...:.||..:|..||
Zfish   135 NFLDNYLYDGEEMADRGNVIVVTFNYRVGALGFMSTGDDGIPGNYGLWDQHAAISWVHRNIKAFG 199

  Fly   219 GDPSSITLLGYGAGAMAVTLHMVSPMSRGLFHKAIVMSGAVTGQWSLPDHQMDVATKQATLLHCH 283
            |:|.:|||.|..|||.:|...:::|.::|:..:||..||.....|::..:....|.:.||.:.|.
Zfish   200 GNPDNITLFGESAGAASVNFQIITPKNKGMIRRAISQSGVALCPWAISRNPRQFAEEIATKVGCP 264

  Fly   284 TENVTEMMDCLK----------GKHYLEFANTLPKMFEFDRNNPLILWKPVIEPDFGQERFLVEE 338
            .:  :.|.||||          ||..|..:...|.:..       :...|||:.|     |:.:|
Zfish   265 ID--SGMADCLKRADPKAVTLAGKLKLTSSPDAPIVHN-------LYLSPVIDGD-----FIPDE 315

  Fly   339 PIRSYQNDDFMKVPIITGMT-KDEFVGPALSILQSPTLLSALN----ENFESLAPVFFMYNTSDA 398
            |...:.|  ...:..|.|:. .|..:...:.|   |::.:||.    |..::||.........||
Zfish   316 PETLFGN--AADIDYIAGVNDMDAHIFATIDI---PSINNALTTTPVEEVQALATALSRDRGQDA 375

  Fly   399 RACNISQELRNHYFPDKLIDANRSLEALSNLYSDALTGFGIHRFVHLAARSTKVYYYRFSYQGAR 463
            ......:...|  :.|| .:..:..:.:..|.:|         ::.|......:|.:..:.:.||
Zfish   376 GIATFQEYTVN--WGDK-PNKEKVKQTVVELETD---------YMFLVPTQAALYLHTDNAKSAR 428

  Fly   464 SHIY-YPEDAP-------YGVVHHDDLMYLFVEPSISRM--FTEDDDEFRMVDIMVRMFSAFAYK 518
            :..| :.|.:.       .|..|.|:|.|:|.:|..:.:  |....|   :...|:..:|.||..
Zfish   429 TFSYLFTESSRIPVFPLWMGADHADELQYVFGKPFATPLGYFPRHRD---VSKYMIAYWSNFAQT 490

  Fly   519 GDPNKPTDLALRDIRWRPFSFKKRYYLDIGKHI---TLEENLNAENYEIWKRLF 569
            |||||.....  .:.|..||.....||||...:   .:::.|.......|..:|
Zfish   491 GDPNKGESKV--PVTWPEFSNPGHQYLDINNKMNKNNVKQMLRTRLVYYWTTVF 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	41..565	CDD:278561	158/568 (28%)
cel.1	NP_955901.2	COesterase	25..517	CDD:306613	150/534 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575568
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.750