Protein Alignment CG4382 and Ces1e

DIOPT Version :9

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_113753.2
• Gene: Ces1e / 29225
• RGDID: 621508
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 624
• Identity: 175/624 - (28%)
• Similarity: 261/624 - (41%)
• Gaps: 129/624 - (20%)

  Fly     4 LCGFVLLLCGLAS----GQNSDEDLSKAIPDEEDPIGSNKELSDLVITTALGKIRGTILPSQSGR 64
            :|.:.|:|..||:    |..|      ::|               |:.|..||:.|..:..:...
  Rat     1 MCLYALILVFLAAFTAGGHPS------SLP---------------VVDTLQGKVLGKYVSLEGFT 44

  Fly    65 NFYA-FRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKC---PQLGLVSGDV--------- 116
            ...| |.|:|:||||:..|||.||:|.|.|....:.|...|.|   |..|.:..|:
  Rat    45 QPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTSYPPMCSQDPVAGQIVNDLLTNREENIS 109

  Fly   117 ---SEDCLRVNIYTKELPSESQPNVRRPVIVFIHPGGFYSLSGQSKNFAGPQYFMNRRLVLVTFN 178
               |||||.:||||   |::.....|.||:|:||.||.  :.|.:..:.|.....:..:|:|...
  Rat   110 LQFSEDCLYLNIYT---PADLTKRDRLPVMVWIHGGGL--VLGGASTYDGLALSTHENVVVVVIQ 169

  Fly   179 YRLGSLGFLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPSSITLLGYGAGAMAVTLHMVSP 243
            ||||..||.:||...:.||.|..|||..|.||:.:|..|||||.|:|:.|..||..:|::.::||
  Rat   170 YRLGIWGFFSTGDEHSRGNWGHLDQVAALHWVQDNIDNFGGDPGSVTIFGESAGGESVSVLVLSP 234

  Fly   244 MSRGLFHKAIVMSGAVTGQWSLPDHQMDVATKQATLLHCHTENVTEMMDCLKGKHYLEFANTLPK 308
            :::.||||||..||.......:..:...:|.|.|.:..|.:.....|:.||:.|...|...|..|
  Rat   235 LAKNLFHKAISESGVALTAGLVKKNTRPLAEKIAVVSGCKSTTSAAMVHCLRQKTEEELLETTLK 299

  Fly   309 --MFEFDRNN---------PLILWKPVIEPDFGQERFLVEEPIRSYQNDDFMKVPIITGMTKDEF 362
              :|..|.:.         |.:| ..|:.|...:| .|.|:        ||..||.|.|:.|.||
  Rat   300 LNLFSLDLHGDSRQSYPFVPTVL-DGVVLPKMPEE-ILAEK--------DFNTVPYIVGINKQEF 354

  Fly   363 ----------------VGP--ALSILQSPTLLSALNENFESLAPVFFMYNTSDARACNISQELRN 409
                            :.|  |.|:|:..:.|..|.|....:|...::.:|.|
  Rat   355 GWILPTMMNYPPSDMKLDPMTATSLLKKSSFLLNLPEEAIPVAVEKYLRHTDD------------ 407

  Fly   410 HYFPDKLIDANRSLEALSNLYSDALTGFGIHRFV----HLAARSTKVYYYRFSYQGARSHIYYPE 470
               ||      |:.:.|..|..|.:  ||:...:    |..| ..:.|.|.|.|:.:.|....|.
  Rat   408 ---PD------RNKDQLLELIGDVI--FGVPSVIVSRGHRDA-GARTYMYEFQYRPSFSSKMKPS 460

  Fly   471 DAPYGVVHHDDLMYLFVEPSISRMFTEDDDEFRMVDIMVRMFSAFAYKGDPN---KPTDLALRDI 532
            ..   |..|.|.:|......|.|..| ..:|..:..:|::.::.||..|:||   .|
  Rat   461 TV---VGDHGDEIYSVFGAPILRGGT-SKEEINLSKMMMKFWANFARNGNPNGQGLP-------- 513

  Fly   533 RWRPFSFKKRYYLDIGKHITLEENLNAENYEIWKRLFPL 571
            .|..:. :|..||.||......:.|..:....|..|..:
  Rat   514 HWPEYD-QKEGYLQIGATTQQAQKLKEKEVAFWSELLAM 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	41..565	CDD:278561	165/575 (29%)
Ces1e	NP_113753.2	COesterase	24..545	CDD:278561	166/587 (28%)
		Aes	43..>239	CDD:223730	75/200 (38%)
		Prevents secretion from ER (Potential)	558..561

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	232	1.000	Domainoid score	I2325
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	232	1.000	Inparanoid score	I3341
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060