Protein Alignment CG4382 and Nlgn3

DIOPT Version :9

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_766520.2
• Gene: Nlgn3 / 245537
• MGIID: 2444609
• Length: 825
• Species: Mus musculus
• Alignment Length: 619
• Identity: 165/619 - (26%)
• Similarity: 266/619 - (42%)
• Gaps: 147/619 - (23%)

  Fly    46 ITTALGKIRG--TILPSQSGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCPQ 108
            :.|..||:||  ..|||:.......:.|:|||.||:...||.||||...|....:||...|.|||
Mouse    41 VNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQ 105

  Fly   109 ------------------LGLVS---GDVSEDCLRVNIYTKELPSESQPNVR------------- 139
                              |.:|:   .:.:||||.:|:|   :|:|.....:
Mouse   106 NIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVY---VPTEDGSGAKKQGEDLADNDGDE 167

  Fly   140 ---------RPVIVFIHPGGFYSLSGQSKNFAGPQYFMNRRLVLVTFNYRLGSLGFLATGTREAP 195
                     :||:|:|| ||.| :.|......|........::::|.|||:|.||||:||.:.|.
Mouse   168 DEDIRDSGAKPVMVYIH-GGSY-MEGTGNMIDGSVLASYGNVIVITLNYRVGVLGFLSTGDQAAK 230

  Fly   196 GNMGLKDQVQLLRWVKLHISRFGGDPSSITLLGYGAGAMAVTLHMVSPMSRGLFHKAIVMSGAVT 260
            ||.||.||:|.||||..:|:.|||||..||:.|.|.||..|:|..:|..|.|||.:||:.||:..
Mouse   231 GNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSAL 295

  Fly   261 GQWSLPDHQMDVATKQATLLHCHTENVTEMMDCLKGKHYLEFA--NTLPKMFEFDRNNPLILWKP 323
            ..|::....:...:..|..:.|:..:..:|:|||:.|...|..  :..|..:.       :.:.|
Mouse   296 SSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYH-------VAFGP 353

  Fly   324 VIEPDFGQERFLVEEPIRSYQNDDFMKVPIITGMTKDEFVGPALSILQSPTLLSALNENFESLAP 388
            ||:.|     .:.::|....:..:|:...|:.|:.:    |..|..::      .:.:..:.::.
Mouse   354 VIDGD-----VIPDDPEILMEQGEFLNYDIMLGVNQ----GEGLKFVE------GVVDPEDGVSG 403

  Fly   389 VFFMYNTSDARACNISQELRNHYFPDKLI------DANRSLEALSNLYSD--------------- 432
            ..|.|:.|:              |.|.|.      |..|  |.:..:|:|
Mouse   404 TDFDYSVSN--------------FVDNLYGYPEGKDTLR--ETIKFMYTDWADRDNPETRRKTLV 452

  Fly   433 ALTGFGIHRFVH-------LAAR-STKVYYYRFSYQGARSHIYYP--EDAPYGVVHHDDLMYLFV 487
            ||  |..|::|.       |.|| .:..|:|.| |...:| :..|  .||.:|    |::.|:|.
Mouse   453 AL--FTDHQWVEPSVVTADLHARYGSPTYFYAF-YHHCQS-LMKPAWSDAAHG----DEVPYVFG 509

  Fly   488 EPSISRM------FTEDDDEFRMVDIMVRMFSAFAYKGDPNKPTDL----------ALRDIRWRP 536
            .|.:...      |:::|  ..:..:::..::.||..||||||...          ...::.|..
Mouse   510 VPMVGPTDLFPCNFSKND--VMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSK 572

  Fly   537 FSFKKRYYLDIGKHITLEENLNAENYEIWKRLFP 570
            ::.:.:.||.||....:.::..|.....||.|.|
Mouse   573 YNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVP 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	41..565	CDD:278561	161/612 (26%)
Nlgn3	NP_766520.2	COesterase	39..601	CDD:365897	161/612 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	151..172		0/20 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	622..668

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832450
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740