Protein Alignment CG4382 and Ces1a

DIOPT Version :9

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_001013786.2
• Gene: Ces1a / 244595
• MGIID: 3648919
• Length: 563
• Species: Mus musculus
• Alignment Length: 606
• Identity: 173/606 - (28%)
• Similarity: 254/606 - (41%)
• Gaps: 144/606 - (23%)

  Fly    45 VITTALGKIRGTILPSQ-SGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCPQ 108
            |:.|..||:.|..:..: |.:....|.|:|:||||:..|||.||:|.|.|....:.|...|.|.|
Mouse    25 VVDTLQGKVMGKYISLEGSAQPVAVFLGVPFAKPPLGPLRFAPPQPAETWSSVKNTTSYPPMCSQ 89

  Fly   109 L---GLVSGDV------------SEDCLRVNIYTKELPSESQPNVRRPVIVFIHPGGFYSLSGQS 158
            :   |.|..||            |||||.:|||:   |::.....|.||:|::|.||.  |||.:
Mouse    90 ITGVGPVLSDVFTNQLENVPLEYSEDCLYLNIYS---PTDLTSKDRLPVMVWVHGGGL--LSGGA 149

  Fly   159 KNFAGPQYFMNRRLVLVTFNYRLGSLGFLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPSS 223
            ..|.|.....:..:|:|...||||..|||:||...:.||.|..|||..|:||:.:|:.|||||||
Mouse   150 STFDGLALSTHENVVIVVIQYRLGIWGFLSTGDEHSRGNWGHLDQVAALQWVQNNIANFGGDPSS 214

  Fly   224 ITLLGYGAGAMAVTLHMVSPMSRGLFHKAIVMSGA--------------------VTGQWSLPDH 268
            :||.|..||..:|::.::||:::.||.:||..||.                    .||
Mouse   215 VTLFGESAGGESVSVLVLSPLTKNLFQRAISESGVALTPCLFRETTRRAAEQVAIATG------- 272

  Fly   269 QMDVATKQATLLHCHTENVTEMMDCLKGKHYLEFANTLP-KMFEFDRNNPLILWKP--------- 323
              .|||..|.::||..|...|.:          .|.||. |.|..|     :|..|
Mouse   273 --CVATTSADIVHCLREKTEEEL----------LATTLKMKFFALD-----LLGDPRESYPFLTT 320

  Fly   324 ----VIEPDFGQERFLVEEPIRSYQNDDFMKVPIITGMTKDEF-------VGPALS--ILQSPTL 375
                |:.|. ..|..|.|:        .|..||.|.|:.|.||       :|..||  .|...:.
Mouse   321 VIDGVVLPK-APEEILAEK--------SFNTVPYIVGINKQEFGWFIPMMMGYPLSEGKLDQKSA 376

  Fly   376 LSALNENFESLAPVFFMYNTSDARACNISQELRNHYFPDKLIDANRSLEALSNLYSD-------A 433
            .|.|.:::    |:           .|||:|| .....:|.:..:...:...:|:.|       |
Mouse   377 TSLLWKSY----PL-----------TNISKEL-TPVATEKYLGGSDCPDKKKDLFLDMMGDVLFA 425

  Fly   434 LTGFGIHRFVHLAARSTKVYYYRFSYQGARSHIYYPED-APYGVV--HHDDLMYLFVEPSISRMF 495
            :....:.|:...|...|  |.|.|.|     |..:..| .|..|:  |.|::..::..|.:....
Mouse   426 VPSVIVARYHRDAGAPT--YMYEFKY-----HPSFVSDMRPKTVIADHGDEVYSVWGTPFLKEGA 483

  Fly   496 TEDDDEFRMVDIMVRMFSAFAYKGDPN---KPTDLALRDIRWRPFSFKKRYYLDIGKHITLEENL 557
            :|  :|..:..:|::.:..||..|:||   .|        .|..:. :|..||.||......:.|
Mouse   484 SE--EEINLSTMMMKFWGNFARNGNPNGEGLP--------HWPEYG-EKESYLQIGATTQQAQRL 537

  Fly   558 NAENYEIWKRLFPLNWRRQTK 578
            ..:....|..|..:.....||
Mouse   538 KDKEVAFWTSLRAMEVGEATK 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	41..565	CDD:278561	169/591 (29%)
Ces1a	NP_001013786.2	Esterase_lipase	25..536	CDD:238191	168/582 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832968
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	228	1.000	Inparanoid score	I3450
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.900