DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4382 and Cel

DIOPT Version :9

Sequence 1:NP_609301.2 Gene:CG4382 / 34279 FlyBaseID:FBgn0032132 Length:580 Species:Drosophila melanogaster
Sequence 2:NP_058693.2 Gene:Cel / 24254 RGDID:2331 Length:612 Species:Rattus norvegicus


Alignment Length:587 Identity:176/587 - (29%)
Similarity:264/587 - (44%) Gaps:124/587 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    36 GSNKELSDLVITTALGKIRGTILPSQSGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDAT 100
            |.||:||.|                 .|.:...|:|||:|....    .:.|:....|..||.||
  Rat    35 GVNKKLSLL-----------------GGDSVDIFKGIPFATAKT----LENPQRHPGWQGTLKAT 78

  Fly   101 FDGPKCPQLGLVSGDV--SEDCLRVNIYTKELPSESQPNVRRPVIVFIHPGGFYSLSGQSKNFA- 162
            ....:|.|..:...|.  .||||.:||:..:  ...|.:...||:|:|:.|.|...|||..||. 
  Rat    79 DFKKRCLQATITQDDTYGQEDCLYLNIWVPQ--GRKQVSHDLPVMVWIYGGAFLMGSGQGANFLK 141

  Fly   163 -----GPQYFMNRRLVLVTFNYRLGSLGFLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPS 222
                 |.:......:::||||||:|.||||:||....|||.||:||...:.|||.:|:.|||||.
  Rat   142 NYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNFGLRDQHMAIAWVKRNIAAFGGDPD 206

  Fly   223 SITLLGYGAGAMAVTLHMVSPMSRGLFHKAIVMSGAVTGQWSLPDHQMDVATKQATLLHCHTENV 287
            :||:.|..|||.:|:|..:||.::||..:||..||.....|::.::.:..|...|..:.|.||:.
  Rat   207 NITIFGESAGAASVSLQTLSPYNKGLIRRAISQSGVALSPWAIQENPLFWAKTIAKKVGCPTEDT 271

  Fly   288 TEMMDCLK--GKHYLEFANTLP-KMFEFDRNNPLI---LWKPVIEPDFGQERFLVEEPIRSYQND 346
            .:|..|||  ....|..|..|| |..|:    |::   .:.||::.|     |:.::||..|.|.
  Rat   272 AKMAGCLKITDPRALTLAYRLPLKSQEY----PIVHYLAFIPVVDGD-----FIPDDPINLYDNA 327

  Fly   347 ---DFM--------------KVPII----TGMTKDEFVGPALSILQSPTLLSALNENFESLAPVF 390
               |::              .||.|    ..:|:::|    ..::...|:...|    :.....|
  Rat   328 ADIDYLAGINDMDGHLFATVDVPAIDKAKQDVTEEDF----YRLVSGHTVAKGL----KGTQATF 384

  Fly   391 FMYNTSDARACNISQELRNHYFPDKLIDANRSLEALSNLYSDALTGFGIHRFVHLA-----ARST 450
            .:|..|.|:  :.|||           :..:::.|..   :|.|  |.|...:.||     |:|.
  Rat   385 DIYTESWAQ--DPSQE-----------NMKKTVVAFE---TDIL--FLIPTEMALAQHRAHAKSA 431

  Fly   451 KVYYYRFSYQGARSHIYYPEDAP--YGVVHHDDLMYLFVEPSISRMFTEDDDEFRMVD-IMVRMF 512
            |.|.|.||:. :|..||     |  .|..|.|||.|:|.:|..:.:.....|  |.|. .|:..:
  Rat   432 KTYSYLFSHP-SRMPIY-----PKWMGADHADDLQYVFGKPFATPLGYRAQD--RTVSKAMIAYW 488

  Fly   513 SAFAYKGDPNK-----PTDLALRDIRWRPFSFKKRYYLDIGKHIT---LEENLNAENYEIWKRLF 569
            :.||..||||.     ||       .|.|::.:...||||.|.||   ::|:|..:..:.|...|
  Rat   489 TNFAKSGDPNMGNSPVPT-------HWYPYTTENGNYLDINKKITSTSMKEHLREKFLKFWAVTF 546

  Fly   570 PL 571
            .:
  Rat   547 EM 548

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4382NP_609301.2 COesterase 41..565 CDD:278561 171/574 (30%)
CelNP_058693.2 COesterase 26..542 CDD:278561 174/579 (30%)
Aes <118..>247 CDD:223730 57/128 (45%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 553..612
4 X 11 AA tandem repeats, O-glycosylated region 556..599
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166336399
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1516
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000017
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.740

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