Protein Alignment CG4382 and Ces1f

DIOPT Version :10

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_659179.1
• Gene: Ces1f / 234564
• MGIID: 2142687
• Length: 561
• Species: Mus musculus
• Alignment Length: 570
• Identity: 168/570 - (29%)
• Similarity: 254/570 - (44%)
• Gaps: 98/570 - (17%)

  Fly    45 VITTALGKIRGTILPSQS-GRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCPQ 108
            |:.||.||:.|..:..:. .:....|.|||:||||:..|||.||:|.|.|....:||...|.|.|
Mouse    25 VVDTAHGKVLGKHVNVEGFSQPVAVFLGIPFAKPPLGSLRFAPPQPAEPWSSVKNATTYPPMCSQ 89

  Fly   109 ---LGLVSGDV------------SEDCLRVNIYTKELPSESQPNVRRPVIVFIHPGGFYSLSGQS 158
               .|....|:            |||||.:||||   |::...|.|.||:|:||.||. .|.|.|
Mouse    90 DAARGQAVNDLITNRKEKIHLEFSEDCLYLNIYT---PADFSKNSRLPVMVWIHGGGL-KLGGAS 150

  Fly   159 KNFAGPQYFMNRRLVLVTFNYRLGSLGFLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPSS 223
             :|.|........:|:|...|||...||.:||...:.||.|..|||..|.||:.:|:.|||||.|
Mouse   151 -SFDGRALSAYENVVVVAIQYRLSIWGFFSTGDEHSRGNWGHLDQVAALHWVQDNIANFGGDPGS 214

  Fly   224 ITLLGYGAGAMAVTLHMVSPMSRGLFHKAIVMSGA--VTGQWSLPDHQMDV--ATKQ-ATLLHCH 283
            :|:.|..||..:|::.::||:|:.|||:||..||.  :.|.::     .||  .|:| |....|.
Mouse   215 VTIFGESAGGYSVSILILSPLSKNLFHRAISESGVAFIPGMFT-----KDVRPITEQIAVTAGCK 274

  Fly   284 TENVTEMMDCLKGKHYLEFANTLPKMFEFDRNNPLILWKPVIEPDF-GQERF---------LVEE 338
            |.....::.|::.|...|....:.|         |.|:|..::.|. ..::|         |.::
Mouse   275 TTTSAVIVHCMRQKTEEELLEIMHK---------LNLYKLSLQGDTKNSDQFVTSVLDGVVLPKD 330

  Fly   339 PIRSYQNDDFMKVPIITGMTKDE--FVGPALS-ILQSPTLLS-----ALNENFESLAPVFFMYNT 395
            |.......:|..||.|.|:.|.|  ::.|.:: .|.:...|.     ||.|.|.|:..:     .
Mouse   331 PKEILAEKNFNTVPYIVGINKQECGWLLPTMTGFLPADVKLDKKKAIALLEQFASMTGI-----P 390

  Fly   396 SDARACNISQELRNHYFPDKLIDANRSLEALSNLYSDALTGFGIHR-FVHLAARSTKVYYYRFSY 459
            .|.....:.:..:....||::.:.  .|:|:.::      .||:.. .|....|.|....|.:.|
Mouse   391 EDIIPVAVEKYTKGSDDPDQIREG--VLDAMGDV------AFGVPSVIVSRGHRDTGAPTYMYEY 447

  Fly   460 QGARSHIYYPE----DAPYGVV--HHDDLMYLFVEPSISRMFTEDDDEFRMVDIMVRMFSAFAYK 518
            |      |||.    ..|..||  |.||:..:|..|.:....:|  :|..:..::::.::.||..
Mouse   448 Q------YYPSFSSPQRPKNVVGDHADDVYSVFGAPILREGASE--EEINLSKMVMKFWANFARN 504

  Fly   519 GDPN---KPTDLALRDIRWRPFSFKKRYYLDIGKHITLEENLNAENYEIW 565
            |:||   .|        .|..:. :|..||.||......:.|..|....|
Mouse   505 GNPNGKGLP--------HWPKYD-QKEGYLHIGGTTQQAQRLKEEEVTFW 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	42..565	CDD:395084	167/568 (29%)
Ces1f	NP_659179.1	COesterase	22..545	CDD:395084	167/568 (29%)
		Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138	558..561