Protein Alignment CG4382 and Nlgn1

DIOPT Version :9

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: XP_006535478.1
• Gene: Nlgn1 / 192167
• MGIID: 2179435
• Length: 863
• Species: Mus musculus
• Alignment Length: 694
• Identity: 184/694 - (26%)
• Similarity: 282/694 - (40%)
• Gaps: 178/694 - (25%)

  Fly     1 MWR---LC------GFVLLLCGLASGQNSDEDLSKAIPDEEDPIGSNKELSDLVITTALGKIRGT 56
            :||   .|      |..|.||.|.....:...||:.: |:.||:          :||..|||||
Mouse    12 VWRAMMACVVHRGSGAPLTLCLLGCLLQTFHVLSQKL-DDVDPL----------VTTNFGKIRG- 64

  Fly    57 ILPSQSGRNFYA----FRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCPQ--------- 108
             :..:.......    |.|:|||.||....|||||||...|.|..:||...|.|||
Mouse    65 -IKKELNNEILGPVIQFLGVPYAAPPTGEHRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPE 128

  Fly   109 ----------LGLVSG---DVSEDCLRVNIY--TKELPSESQPNVR------------------- 139
                      |.:||.   |.|||||.:|||  |:::...|:...|
Mouse   129 VMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDVKRISKECARKPGKKICRKGGPLTKKHTD 193

  Fly   140 -------------------RPVIVFIHPGGFYSLSGQSKNFAGPQYFMNRRLVLVTFNYRLGSLG 185
                               :||:|:|| ||.| :.|....:.|........::::|.|||||.||
Mouse   194 DLGDNDGAEDEDIRDSGGPKPVMVYIH-GGSY-MEGTGNLYDGSVLASYGNVIVITVNYRLGVLG 256

  Fly   186 FLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPSSITLLGYGAGAMAVTLHMVSPMS----- 245
            ||:||.:.|.||.||.|.:|.|||...:|..|||||..||:.|.|||...|.|..:|..|
Mouse   257 FLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRW 321

  Fly   246 ----RGLFHKAIVMSGAVTGQWSLPDHQMDVATKQATLLHCHTENVTEMMDCLKGKHYLEFA--N 304
                :|||.:||..||.....|::.......|...||.:.|:..:..|:::||:.|.|.|..  :
Mouse   322 SNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARILATKVGCNVSDTVELVECLQKKPYKELVDQD 386

  Fly   305 TLPKMFEFDRNNPLILWKPVIEPDFGQERFLVEEPIRSYQNDDFMKVPIITGMTKDEFVGPALSI 369
            ..|..:.       |.:.|||:.|     .:.::|....:..:|:...|:.|:.:.|.:....:|
Mouse   387 VQPARYH-------IAFGPVIDGD-----VIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENI 439

  Fly   370 LQSPTLLSALNENFESLAPVFFMYNTSDARACNISQELRNHY-FPDKLIDANRSLEALSNLYSD- 432
            :.|...:||.:.:|.                  :|..:.|.| :|:.. |..|  |.:..:|:|
Mouse   440 VDSDDGVSASDFDFA------------------VSNFVDNLYGYPEGK-DVLR--ETIKFMYTDW 483

  Fly   433 ------------ALTGFGIHRFVHLAARS--------TKVYYYRFSYQGARSHIYYPEDAPYGVV 477
                        .|..|..|::|..|..:        :..|:|.|.:......:....||.:|
Mouse   484 ADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSPTYFYAFYHHCQTDQVPAWADAAHG-- 546

  Fly   478 HHDDLMYLFVEPSISRM------FTEDDDEFRMVDIMVRMFSAFAYKGDPNKPTDL--------- 527
              |::.|:...|.|...      |:::|  ..:..:::..::.||..||||:|...
Mouse   547 --DEVPYVLGIPMIGPTELFPCNFSKND--VMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKP 607

  Fly   528 -ALRDIRWRPFSFKKRYYLDIGKHITLEENLNAENYEIWKRLFP 570
             ...::.|..:|.|.:.||.||....::|:..|....:|..|.|
Mouse   608 NRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRANKVNLWLELVP 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	41..565	CDD:278561	168/638 (26%)
Nlgn1	XP_006535478.1	COesterase	53..646	CDD:365897	169/645 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832535
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740