Protein Alignment CG4382 and ace-1

DIOPT Version :10

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_510660.1
• Gene: ace-1 / 181706
• WormBaseID: WBGene00000035
• Length: 620
• Species: Caenorhabditis elegans
• Alignment Length: 599
• Identity: 162/599 - (27%)
• Similarity: 262/599 - (43%)
• Gaps: 131/599 - (21%)

  Fly    60 SQSGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCPQ-----LGLVSGD---- 115
            ||:|:....|:|||:|:|||..|||:.|:|.:.|...|:||.....|.|     .|...|.
 Worm    36 SQTGKPLTRFQGIPFAEPPVGNLRFKKPKPKQPWRIPLNATTPPNSCIQSEDTYFGDFYGSTMWN 100

  Fly   116 ----VSEDCLRVNIYTKELPSESQPNVRRPVIVFIHPGGFYSLSGQSKNFAGPQYFMNRRLVLVT 176
                :|||||.:|:|   :|.:..||.:..|:|:::.|||:|.:.....:.|....:...::||.
 Worm   101 ANTKLSEDCLYLNVY---VPGKVDPNKKLAVMVWVYGGGFWSGTATLDVYDGRILTVEENVILVA 162

  Fly   177 FNYRLGSLGFLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPSSITLLGYGAGAMAVTLHMV 241
            .|||:...|||.....|||||||:.||:..::||..:|..||||.|.|||.|..|||.:|::||:
 Worm   163 MNYRVSIFGFLYMNRPEAPGNMGMWDQLLAMKWVHKNIDLFGGDLSRITLFGESAGAASVSIHML 227

  Fly   242 SPMSRGLFHKAIVMSGAVTGQWSLPDHQMDVATKQATLLH----CHTENV-----TEMMDCLKGK 297
            ||.|...||:||:.||:.|..|::  ...|||..:|.:|:    |...::     ..::||.:..
 Worm   228 SPKSAPYFHRAIIQSGSATSPWAI--EPRDVALARAVILYNAMKCGNMSLINPDYDRILDCFQRA 290

  Fly   298 HYLEFANTLPKMFEFDRNN---PL-----ILWKPVIEPDFGQERFLVEEPIRSYQNDDFMKVPII 354
            .    |:.|       |.|   |:     ..|.||::.|     ||:|....|.:..:|.|..::
 Worm   291 D----ADAL-------RENEWAPVREFGDFPWVPVVDGD-----FLLENAQTSLKQGNFKKTQLL 339

  Fly   355 TGMTKDEFVGPALSILQSPTLLSALNENFESLAPVFFMYNTSD-------------------ARA 400
            .|..:||.:             ..|......:.||...:..:|                   ...
 Worm   340 AGSNRDESI-------------YFLTYQLPDIFPVADFFTKTDFIKDRQLWIKGVKDLLPRQILK 391

  Fly   401 CNIS-QELRNHYFPDKLIDANRS-LEALSNLYSDALTGFGIHRFV----HLAARSTK----VYYY 455
            |.:: ..:.:.|.|..|....|. :.|:..:..|       :.|.    .:|...||    .|||
 Worm   392 CQLTLAAVLHEYEPQDLPVTPRDWINAMDKMLGD-------YHFTCSVNEMALAHTKHGGDTYYY 449

  Fly   456 RFSYQGARSHIYYPEDAPYGVVHHDDLMYLFVEPSISRMFTEDDDEFRMVDIMVRMFSAFAYKGD 520
            .|:::.::.  .:||  ..||:|..::.::|.||...:.|...|:|..:.:..:|.::.||..||
 Worm   450 YFTHRASQQ--TWPE--WMGVLHGYEINFIFGEPLNQKRFNYTDEERELSNRFMRYWANFAKTGD 510

  Fly   521 PNKPTDLALRDIRWRPFSFKKRYYLDIGKHITLEENL----------NAENYEIWKRLFP----- 570
            |||..|.:.....|..::.....|:    ::|:|.:.          ..:....||...|
 Worm   511 PNKNEDGSFTQDVWPKYNSVSMEYM----NMTVESSYPSMKRIGHGPRRKECAFWKAYLPNLMAA 571

  Fly   571 --------LNWRRQ 576
                    |.|::|
 Worm   572 VADVGDPYLVWKQQ 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	42..565	CDD:395084	156/573 (27%)
ace-1	NP_510660.1	Esterase_lipase	20..543	CDD:238191	156/555 (28%)