Protein Alignment CG4382 and cest-19

DIOPT Version :9

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_509187.4
• Gene: cest-19 / 180973
• WormBaseID: WBGene00020125
• Length: 607
• Species: Caenorhabditis elegans
• Alignment Length: 600
• Identity: 176/600 - (29%)
• Similarity: 264/600 - (44%)
• Gaps: 135/600 - (22%)

  Fly    37 SNKELSDLVITTALGKIRGTILPSQSGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATF 101
            |.:.:|...:....|.|||..|.: .|:::..|:|||:|.|||..||||.|:...:|...::||.
 Worm    19 STRHISPFELRVNSGAIRGERLLT-DGQDYSVFKGIPFAMPPVGYLRFQMPKEPAKWRGVMNATQ 82

  Fly   102 DGPKCPQLGLVSGD----------VSEDCLRVNIYTKELPSESQ-PNVRRPVIVFIHPGGFYSLS 155
            ....|.| .:...|          ||||||.:|:::   |:..| .|...|||||||.|.|.:.|
 Worm    83 YSAMCMQ-NIDENDAGEPERYVAHVSEDCLYLNVFS---PTPYQYTNDTYPVIVFIHGGRFQTGS 143

  Fly   156 GQSKNFAGPQ-----YFMNRRLVLVTFNYRLGSLGFLATGTREAPGNMGLKDQVQLLRWVKLHIS 215
            |...    ||     .|::|::|.||||||||.|||.:||....|||:||.||:..|:|||.:..
 Worm   144 GSDI----PQRAILSNFVSRKIVFVTFNYRLGPLGFASTGDSVLPGNIGLWDQIWALKWVKANAE 204

  Fly   216 RFGGDPSSITLLGYGAGAMAVTLHMVSPMSRGLFHKAIVMSGA-----------VTGQWSLPDHQ 269
            .||||||:|.|:|:|.||.:.:|..:||.:.|||.|.::|||:           |...|::.|.
 Worm   205 VFGGDPSNILLMGHGTGAASASLLALSPRAEGLFQKVLLMSGSALQPGVVRNTQVNATWNMNDR- 268

  Fly   270 MDVATKQATLLHCHTENVTEMMDCLKGKHYLEFANTLPKMFEFDRNNPLILWKPVIEPDFGQERF 334
                      ..|...|.:|::||.:.:...|....  |...||.....:   |:|:   |....
 Worm   269 ----------FGCRAFNSSELLDCARKRSKEEIFQY--KRLHFDDYEEFV---PIID---GVGGI 315

  Fly   335 LVEEP--IRSYQNDDFMKVPIITGMTKDEFVGPALSILQSPTLLSALNENFESLAPVFFMYNTSD 397
            |.|.|  :..::.    |.||:.|.||||   .:|.||    ||:..:.||.|:.     :...:
 Worm   316 LPEPPEQLTLHRR----KTPIVIGTTKDE---SSLRIL----LLNEKDLNFSSIT-----WENGE 364

  Fly   398 ARACN-------------ISQELRNHY--------FPDKLIDANRSLEALSNLYSDALTGFGIHR 441
            ..|.|             |||..::.|        ||:.::     ..:|..:||        |.
 Worm   365 TLADNLTLGFKQFQNHRLISQGCKSEYVWTQVDPSFPESVL-----FNSLLKMYS--------HF 416

  Fly   442 FVHLAARSTKVYY-------YRFSYQGARSHIYYPEDAPYGVVHHDDLMYLF-VEPSISRMFTED 498
            :....|.....||       |.:|:.....:.|..:.|.:||    |.:::| |.|   |...:.
 Worm   417 WYDAPASQLATYYLKHDLPVYLYSFDHISENFYDIDRAFHGV----DKLHIFNVTP---RFLNKR 474

  Fly   499 DD-----EFRMVDIMVRMFSAFAYKGDPNKPTDLALRDIRWRPFSFKKRYYLDIGKHITLEENLN 558
            .|     :.|:|:|...:.:.||..|.|....|..  ...|...:.|:..||.|....:::....
 Worm   475 KDMNWQLDQRVVEIFSELVANFALYGTPTHENDGF--SFNWTSTTAKELSYLSITDSPSMQVGYR 537

  Fly   559 AENYEIWKRLFPLNW 573
            .:.:..|      ||
 Worm   538 WQGHVFW------NW 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	41..565	CDD:278561	172/586 (29%)
cest-19	NP_509187.4	Abhydrolase	27..544	CDD:389770	171/582 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R17041
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.940