Protein Alignment CG4382 and cest-16

DIOPT Version :9

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_741812.2
• Gene: cest-16 / 180905
• WormBaseID: WBGene00020330
• Length: 697
• Species: Caenorhabditis elegans
• Alignment Length: 653
• Identity: 154/653 - (23%)
• Similarity: 264/653 - (40%)
• Gaps: 179/653 - (27%)

  Fly    51 GKIRGTILPSQSGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCPQ-LGLVSG 114
            |.:||.|. :..|::...|||:|||:||:..|||:||....:|...|.|...||.|.| :.....
 Worm    31 GLVRGNIY-NIDGKHIQIFRGVPYAEPPIGELRFKPPVKKTRWHQELPAVEYGPPCLQFMDFHKN 94

  Fly   115 D---------VSEDCLRVNIYTK-ELPSESQPNVRRPVIVFIHPGGFYSLSGQSKNFAGPQY--- 166
            |         .|||||.:|:::. :...||:   ..|::|:||.|.|  |:|.:......:.
 Worm    95 DKFAKTNMDRQSEDCLYLNVFSPYDTDDESK---TYPILVWIHGGSF--LAGSADTGIDMEVIAA 154

  Fly   167 -FMNRRLVLVTFNYRLGSLGFL--ATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPSSITLLG 228
             .:::.:..|:.|||||.|||:  ..|.: ..||.|:.|.|..|:|::.:|.:|.|||:.:|::|
 Worm   155 NIVSKGIAFVSINYRLGPLGFMNYQNGDK-LEGNFGIWDMVMALQWIQSNIKQFNGDPTKVTVMG 218

  Fly   229 YGAGAMAVTLHMVSPMSRGLFHKAIVMSGAVTGQWSL-----PDHQMD----------------- 271
            ..||..|.:|..:||.:.||.|:||:|||:....|::     |.:.:|
 Worm   219 ESAGGAASSLLALSPKTSGLLHQAIIMSGSSMAGWAIHRHSQPAYSVDNLVAYFRCEKWINEDDT 283

  Fly   272 -------------------VATKQATLLHCHTENVTEM--MDCLKGKHYLEFANTLPKMFEFDRN 315
                               :...|...::|.|:::|:|  |:||:.              |.:.:
 Worm   284 KEVVGDEYQHLTHSVIRSALCNYQNVKINCLTDDMTQMDKMNCLRK--------------ELNFS 334

  Fly   316 NPLILWKPVIEPDFGQERFLVE------EPIRSYQNDDFMKVPIITGMTKDEFVGPALSIL---- 370
            :|  |::..:..:.|..:.:|:      ..:...:|:  .::||:||:.:.|: |...::.
 Worm   335 SP--LFRKALAAELGVSKMVVDGDLVPSSGVSLVRNN--ARIPIMTGVARKEW-GHKKAMFYNMH 394

  Fly   371 -QSPTLLSALNENFESLAPVFFMYNTSDARACNISQEL-------------RNHYFPDKLIDANR 421
             :.....|.:.|....:....| :.|:..:..|.:.:|             .|.:..|:::.|.:
 Worm   395 QRDGLKRSDVEEQVYRIIDNSF-HETASEKLANSTVQLIANATIVRYLETPNNEFIADQVVGALQ 458

  Fly   422 SLEALSNLYSDALTGFGIHRFV-----HLAA---RSTKVYYYRFSYQGARSHIYYPEDAPYGV-- 476
            .||      ||.       .||     .:||   :...||.|.|.|. .:|.|...|...|.:
 Worm   459 KLE------SDI-------EFVAPCEREVAAYVDKGVPVYLYSFDYV-PKSPILESERKIYSLFG 509

  Fly   477 -------------------VHHDDLMYLF---------VEPSISRMFTEDDDEFRMVDIMVRMFS 513
                               .|..|..::|         :.|...|       |..|..|:..|.:
 Worm   510 TKPVEMKRTEKSEILEKAAFHGLDHAFIFSKGYSSNFEISPYTKR-------EETMSKILCTMLT 567

  Fly   514 AFAYKGDPNKPTDLALRDIRWRPFSFKKRYY--LDIGKHITLEENLNAENYEIWKRLFPLNWRRQ 576
            .|...|||:...      ..|..||.....|  ||:...: ||..::..:.:.|.....|..|..
 Worm   568 NFVKNGDPSTTR------FSWPIFSGNSSQYVSLDVPLKL-LEGEIHFPDAQFWNTEAELITRYV 625

  Fly   577 TKE 579
            :|:
 Worm   626 SKD 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	41..565	CDD:278561	150/637 (24%)
cest-16	NP_741812.2	Abhydrolase	25..608	CDD:389770	150/631 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.010