Protein Alignment CG4382 and cest-2.1

DIOPT Version :10

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_506508.2
• Gene: cest-2.1 / 179916
• WormBaseID: WBGene00013875
• Length: 675
• Species: Caenorhabditis elegans
• Alignment Length: 593
• Identity: 151/593 - (25%)
• Similarity: 250/593 - (42%)
• Gaps: 153/593 - (25%)

  Fly    46 ITTALGKIRGTILPSQ----SGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKC 106
            :..:.|.|.|.||.|.    .......|.|||:.:||...|||:.|.|...|...|:.....|.|
 Worm    21 VQLSTGTIEGKILTSTYSPLGNHTGIGFLGIPFVEPPAGNLRFRKPRPPIPWDGILETKEYKPAC 85

  Fly   107 ------PQLGLVSGDVSEDCLRVNIYTKELPSESQPNVRR---PVIVFIHPGGFYSLSGQSKNFA 162
                  .....|.|.:|||||..|::|      :|..::|   .|::.:|.|...:.|..:.|
 Worm    86 MSDAKKTYKNGVGGPISEDCLYANVFT------NQYCMKRKNCSVMIVVHGGRILTESASAFN-- 142

  Fly   163 GPQYFMN------RRLVLVTFNYRLGSLGFLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDP 221
             |:..:|      |.:|:||||||||:.||......:...|:|:.|.::.::|.:..:..|||:.
 Worm   143 -PEILVNNFVGQGRNIVVVTFNYRLGTFGFGVLNGEKGDSNVGMFDMLEAVKWTRKEVHNFGGNK 206

  Fly   222 SSITLLGYGAGAMAVTLHMVSPMSRGLFHKAIVMSGAVTGQWSLPDHQMDVATKQATLLHCHTEN 286
            ..:|::|:.||...|.....||:|:|:.::.|:||||:        :||.   |.|..     :.
 Worm   207 DKLTMVGHSAGGSLVGAFTSSPLSKGMLNQQIIMSGAL--------YQMG---KLANF-----KG 255

  Fly   287 VTEMMDCLKGKHYLEFANTLPKMFEFDRNNPLILWK--PVIEPDFGQERFLVEEPIRSYQNDD-F 348
            :|.|         .:.|..||::|.|.:.:.:.:.|  ..:.....||  :::..:...||.. :
 Worm   256 MTAM---------AQKAGCLPEVFGFRKLSQVRIDKTYSCLRNISAQE--VLDAQLWVLQNTTYY 309

  Fly   349 MKVPIITGMTKDEFVGPALSILQSPTLLSALNENFESLA-----PVFFMYNTSDARACNISQELR 408
            :.||.|.|    ||:               ||.:.|.||     |:..|..|:.|       |||
 Worm   310 ISVPHIDG----EFL---------------LNYSDEILASGTIHPINSMIGTTTA-------ELR 348

  Fly   409 NHYFPDKLIDANRSLEALSNL--------------------------------------YSDALT 435
            :..:.:.|.:|::..|.|.||                                      |..::.
 Worm   349 DPIYINDLKNADKKEELLKNLCEHIGYELYTEPEEFSRKCQKFYGNGDDAQFLADDMEFYDGSIK 413

  Fly   436 GFGIHRFVHLAARSTKVYYYRFSYQ--GARSHIYYPEDAPYGVVHHDDLMYLFVEPSISR-MFTE 497
            ....|     |:::|||:.|.:.|:  |.....|.....|:   |.:||:|:|   ..|| .|||
 Worm   414 VANAH-----ASKNTKVFMYSYDYKDAGPAFKKYAQAPPPH---HSEDLIYVF---GTSRGNFTE 467

  Fly   498 DDDEFRMVDIMVRMFSAFAYKGDPNKPTDLALRDIRWRPFSFKKRYY--LDIGKHITL---EENL 557
            .|  :.:..|...||:.|...|:|: |:    ::.:|:.:|.:||.|  :|..|:.|:   .:..
 Worm   468 KD--YVIEQIYSGMFADFVNFGNPS-PS----KEQKWKEYSPEKREYFLIDFDKNFTMPGTRDGY 525

  Fly   558 NAENYEIW 565
            .:...|.|
 Worm   526 YSRALEFW 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	42..565	CDD:395084	150/591 (25%)
cest-2.1	NP_506508.2	COesterase	18..533	CDD:395084	150/591 (25%)