Protein Alignment CG4382 and cest-2.1

DIOPT Version :9

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_506508.2
• Gene: cest-2.1 / 179916
• WormBaseID: WBGene00013875
• Length: 675
• Species: Caenorhabditis elegans
• Alignment Length: 593
• Identity: 151/593 - (25%)
• Similarity: 250/593 - (42%)
• Gaps: 153/593 - (25%)

  Fly    46 ITTALGKIRGTILPSQ----SGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKC 106
            :..:.|.|.|.||.|.    .......|.|||:.:||...|||:.|.|...|...|:.....|.|
 Worm    21 VQLSTGTIEGKILTSTYSPLGNHTGIGFLGIPFVEPPAGNLRFRKPRPPIPWDGILETKEYKPAC 85

  Fly   107 ------PQLGLVSGDVSEDCLRVNIYTKELPSESQPNVRR---PVIVFIHPGGFYSLSGQSKNFA 162
                  .....|.|.:|||||..|::|      :|..::|   .|::.:|.|...:.|..:.|
 Worm    86 MSDAKKTYKNGVGGPISEDCLYANVFT------NQYCMKRKNCSVMIVVHGGRILTESASAFN-- 142

  Fly   163 GPQYFMN------RRLVLVTFNYRLGSLGFLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDP 221
             |:..:|      |.:|:||||||||:.||......:...|:|:.|.::.::|.:..:..|||:.
 Worm   143 -PEILVNNFVGQGRNIVVVTFNYRLGTFGFGVLNGEKGDSNVGMFDMLEAVKWTRKEVHNFGGNK 206

  Fly   222 SSITLLGYGAGAMAVTLHMVSPMSRGLFHKAIVMSGAVTGQWSLPDHQMDVATKQATLLHCHTEN 286
            ..:|::|:.||...|.....||:|:|:.::.|:||||:        :||.   |.|..     :.
 Worm   207 DKLTMVGHSAGGSLVGAFTSSPLSKGMLNQQIIMSGAL--------YQMG---KLANF-----KG 255

  Fly   287 VTEMMDCLKGKHYLEFANTLPKMFEFDRNNPLILWK--PVIEPDFGQERFLVEEPIRSYQNDD-F 348
            :|.|         .:.|..||::|.|.:.:.:.:.|  ..:.....||  :::..:...||.. :
 Worm   256 MTAM---------AQKAGCLPEVFGFRKLSQVRIDKTYSCLRNISAQE--VLDAQLWVLQNTTYY 309

  Fly   349 MKVPIITGMTKDEFVGPALSILQSPTLLSALNENFESLA-----PVFFMYNTSDARACNISQELR 408
            :.||.|.|    ||:               ||.:.|.||     |:..|..|:.|       |||
 Worm   310 ISVPHIDG----EFL---------------LNYSDEILASGTIHPINSMIGTTTA-------ELR 348

  Fly   409 NHYFPDKLIDANRSLEALSNL--------------------------------------YSDALT 435
            :..:.:.|.:|::..|.|.||                                      |..::.
 Worm   349 DPIYINDLKNADKKEELLKNLCEHIGYELYTEPEEFSRKCQKFYGNGDDAQFLADDMEFYDGSIK 413

  Fly   436 GFGIHRFVHLAARSTKVYYYRFSYQ--GARSHIYYPEDAPYGVVHHDDLMYLFVEPSISR-MFTE 497
            ....|     |:::|||:.|.:.|:  |.....|.....|:   |.:||:|:|   ..|| .|||
 Worm   414 VANAH-----ASKNTKVFMYSYDYKDAGPAFKKYAQAPPPH---HSEDLIYVF---GTSRGNFTE 467

  Fly   498 DDDEFRMVDIMVRMFSAFAYKGDPNKPTDLALRDIRWRPFSFKKRYY--LDIGKHITL---EENL 557
            .|  :.:..|...||:.|...|:|: |:    ::.:|:.:|.:||.|  :|..|:.|:   .:..
 Worm   468 KD--YVIEQIYSGMFADFVNFGNPS-PS----KEQKWKEYSPEKREYFLIDFDKNFTMPGTRDGY 525

  Fly   558 NAENYEIW 565
            .:...|.|
 Worm   526 YSRALEFW 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	41..565	CDD:278561	150/591 (25%)
cest-2.1	NP_506508.2	COesterase	21..533	CDD:365897	150/591 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157081
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.840