Protein Alignment CG4382 and cest-1.2

DIOPT Version :9

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_506504.2
• Gene: cest-1.2 / 179914
• WormBaseID: WBGene00011364
• Length: 676
• Species: Caenorhabditis elegans
• Alignment Length: 574
• Identity: 155/574 - (27%)
• Similarity: 247/574 - (43%)
• Gaps: 92/574 - (16%)

  Fly    46 ITTALGKIRGTILPSQ----SGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKC 106
            :..:.|.|.|..|.|.    ..::..||.||||.:||:..|||:.|.|.:.|...|:.....|.|
 Worm    21 VQLSTGIIEGKQLNSTYSPFGNQSAIAFLGIPYVEPPIGDLRFRKPRPQKTWSGVLETKKFKPAC 85

  Fly   107 P-------QLGLVSGDVSEDCLRVNIYTKELPSESQPNVRRPVIVFIHPGGFYSLSGQS------ 158
            .       :.|.:.|.:|||||.:|:.|.:...|   |....|::.:|.||:...|..:
 Worm    86 MSNSTKTYKNGGIGGPISEDCLYLNVLTNQYCLE---NKNCSVVIIVHGGGYLFESAATFNHEIL 147

  Fly   159 -KNFAGPQYFMNRRLVLVTFNYRLGSLGFLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPS 222
             .||.|    .:|.:|:||.|||||..||......|...|:|:.|.::.::||:..|.:|||:..
 Worm   148 VNNFVG----QDRNIVVVTINYRLGIFGFGHLNGFEGDKNVGIFDTLEAVKWVRREIKQFGGNKD 208

  Fly   223 SITLLGYGAGAMAVTLHMVSPMSRGLFHKAIVMSGAVTGQWSLPDHQMDVATKQATLLHCHTE-- 285
            .|||.|:.|||..|....:||:::||.|:.|||||.:|......:.:  ..|..|..:.||::
 Worm   209 RITLAGHSAGAGVVAAFTISPLTKGLIHQQIVMSGPMTNMSKKSNFK--GMTAMAERVGCHSKKY 271

  Fly   286 --------NVTEMMDCLKGKHYLEFANTLPKMFEFDRNNPLILWKPVIEPDFGQERFLVEEPIRS 342
                    .|.::..||:.|...|.   |.......:|:......|.::.:     |:.:.|...
 Worm   272 GFNKLPEHEVEQVYSCLRKKPAQEL---LDAQLWLLQNSTFYFGAPPVDGE-----FITDYPDNL 328

  Fly   343 YQNDDFMKVPIITGMTKDEFVGPALSILQSPTLLSALNENFESL-APVFFMYNTSDARACNISQE 406
            |.......:..:.|.|..|        ||....:|  |.|:... ....|:.|..|.....|.:|
 Worm   329 YSEKSIFSINTLLGTTTRE--------LQDTGYIS--NSNYSKFETKETFLKNLCDQIGIEIYKE 383

  Fly   407 LRNHYFPDK----LIDA--NRSLEALSNLYSDALTGFGIHRFVHLAARSTKVYYYRFSYQGARSH 465
            ..:  |..|    .|:.  ::||......|:.|:.....|     |.:..|||.|.::|.||...
 Worm   384 SED--FSSKCQKWYINGSDSKSLSDDMEFYTQAINLADAH-----ARKGKKVYMYSYAYSGAGPA 441

  Fly   466 I--YYPEDAPYGVVHHDDLMYLFVEPSISRMFTEDDDEFRMVDIMVRMFSAFAYKGDPNKPTDLA 528
            .  |....:|:   |.:||:|.|  .:...:|...|  :.:..|...||:.|....||:..||..
 Worm   442 FKKYMKVKSPH---HSEDLIYTF--GTHRGVFAPKD--YVIEYIYSGMFADFINFEDPSPSTDQP 499

  Fly   529 LRDIRWRPFSFK-KRYYL-DIGKHIT---LEENLNAENYEIW----KRLFPLNW 573
                 |..::.: |.|:| |..:::|   :::|..|:.||.|    ::.|...|
 Worm   500 -----WLQYTKENKEYFLVDFDQNLTMPGMKKNYYAKAYEFWSTAGQKSFKEEW 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	41..565	CDD:278561	152/560 (27%)
cest-1.2	NP_506504.2	COesterase	21..536	CDD:278561	152/560 (27%)
		Aes	<125..>250	CDD:223730	48/128 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157064
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840