Protein Alignment CG4382 and cest-34

DIOPT Version :9

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_001360105.1
• Gene: cest-34 / 179057
• WormBaseID: WBGene00019652
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 605
• Identity: 168/605 - (27%)
• Similarity: 257/605 - (42%)
• Gaps: 135/605 - (22%)

  Fly    33 DPIGSNKELSDLVITTALGKIRGTILPSQSGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDTL 97
            :|:|:       |:.|:.|.:.|. |.....:..:.:.|:||||||...:||..|.|.:.|.:|.
 Worm    11 EPLGT-------VLNTSCGPVLGN-LYRHGDKEVHGYLGMPYAKPPTGEMRFAKPVPADDWTETR 67

  Fly    98 DATFDGPKCPQLG-------LVSGDVSEDC--LRVNIYTKELPSESQPNVRRPVIVFIHPGGFYS 153
            |.|..||:||..|       .|:.|..::.  |.||::.....|....|. |||:|::|.|||..
 Worm    68 DCTKYGPRCPPSGQGLEKGMFVNPDEPDEANGLSVNVFVPGWESSEYKNA-RPVMVYVHGGGFEI 131

  Fly   154 LSGQSKNFAGPQYFMNRRL-----VLVTFNYRLGSLGFLATGTREAPGNMGLKDQVQLLRWVKLH 213
            .|  |:.|.  .|.::..|     :|||.|||||.|||..||....|||.||.||...|:||:.|
 Worm   132 SS--SREFC--DYSISSTLPMKDVILVTMNYRLGILGFFTTGDEVCPGNFGLWDQTLALQWVQKH 192

  Fly   214 ISRFGGDPSSITLLGYGAGAMAVTLHMVSPMSRGLFHKAIVMSGAVTGQWSLPDHQMDVATKQAT 278
            |:.|||||:::||.|..||...|.|..:||.||.||.|.:.|||:     ::.:..|..|..:|
 Worm   193 IASFGGDPNNVTLFGQSAGGACVDLLTLSPHSRDLFQKVVPMSGS-----AMCEFAMRTAENEA- 251

  Fly   279 LLHCHTENVTEMMDCLKG-KHYLEFANTLP--KM-----FEFDRNNPLILWKPVIEPDFGQERFL 335
              |...:.:..:.....| |..|||..:||  |:     :.:.::..:.|. |..:.||
 Worm   252 --HVFDDILARLGFTGSGSKERLEFMRSLPCDKITGKTGYTYKQSGFMSLC-PNYDGDF------ 307

  Fly   336 VEEPIRSYQNDDFMKVPIITGMTKDEFVGPALSILQSPTLLSALNEN------------------ 382
            ..:|:...:.|...:: ::||:..:|            .||.|.:.|
 Worm   308 FPKPLDELRKDASKRI-LMTGIVGNE------------GLLFAFDRNTPYKDYTDLLRLKIEEDY 359

  Fly   383 -------FESLAPVFFMYNTSDARACNISQELRNHYFPDKLIDANRSLEALSNLYSDALTGFGIH 440
                   .|.:....|.|.|.     |||:.           |....:...:....|::...|:.
 Worm   360 KEDVVDDVEGIRKEIFEYYTK-----NISEG-----------DEEAIMRKAAEFVGDSIFHTGVR 408

  Fly   441 RFVHLAA-RSTKVYYYRFSY---------QGARSHIYYPEDAPYGVVHHDDLMYLFVEPSISRMF 495
            .....|| ...:|:.|.|.|         :|     |.|...|   .|..:|.|||.:..||: |
 Worm   409 ATAQNAAEHGDEVWLYNFDYCNPDGFAPLKG-----YLPYIEP---THGMELRYLFGDGIISK-F 464

  Fly   496 TEDDDEFRMVDIMVRMFSAFAYKGDPNKPTDLALRDIRWRPFSFKK--RYYLDIGKHITLEENLN 558
            ...::|.:|:|....||:.||..|:||:....|     |..|...:  |:|.....:..:|:..:
 Worm   465 EPTEEELKMLDKFTTMFANFAKYGNPNETGSSA-----WEKFDPARPGRHYRISYPNSGMEDEFS 524

  Fly   559 AENYEIWKRLFPLNWRRQTK 578
            ...   ||.|..:  |::.|
 Worm   525 GGR---WKFLEEI--RKKNK 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	41..565	CDD:278561	161/582 (28%)
cest-34	NP_001360105.1	COesterase	15..530	CDD:365897	162/588 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810