Protein Alignment CG4382 and cest-35.1

DIOPT Version :9

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_504400.1
• Gene: cest-35.1 / 178912
• WormBaseID: WBGene00015067
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 574
• Identity: 160/574 - (27%)
• Similarity: 236/574 - (41%)
• Gaps: 118/574 - (20%)

  Fly    45 VITTALGKIRGTILPSQSGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCPQL 109
            |:..:.|.|||.|. ....:....:.|||:||.|:..|||:.....|:|.:.||....||.|||.
 Worm    16 VLNASCGPIRGNIY-EHDDKIVDGYLGIPFAKAPIGELRFKKSVEAEKWTEPLDCYKYGPGCPQS 79

  Fly   110 GLVSG----------DVSED-CLRVNIYTKELPSESQPNVRRPVIVFIHPGGF----------YS 153
            |.:..          :.:|| ||.:|::..:..|...|| ..||||:.:.|||          ||
 Worm    80 GALGAMIVPQASAIREFAEDNCLTLNVFAPKWKSAEFPN-GLPVIVYFYGGGFEVGFSSMFDDYS 143

  Fly   154 LSGQSKNFAGPQYFMNRRLVLVTFNYRLGSLGFLATGTREAPGNMGLKDQVQLLRWVKLHISRFG 218
            |:|.         ...:.::|||.|||:|.|||.|||...:.||.||.||...|:||:.||..||
 Worm   144 LTGT---------LPLKDVILVTPNYRIGPLGFFATGDDVSRGNWGLWDQALALQWVQKHIKSFG 199

  Fly   219 GDPSSITLLGYGAGAMAVTLHMVSPMSRGLFHKAIVMSGAVTGQWSL-------------PDHQM 270
            ||||::|:.|..||..:|....:||.:...|||.|.||||.|..:.:             ..|..
 Worm   200 GDPSNVTISGTSAGGASVDFLSLSPHANKYFHKFIPMSGAATCPFGIRSKDVEGLIFREFAKHHG 264

  Fly   271 DVATKQATLLHCHTENVTEMMDCLKGKHYLEFANTLPKMFEFDRNNPLILWKPVIEPDFGQERFL 335
            .......:|||.:.....|:....:|     |......||.|         .|..:.||..:.|
 Worm   265 YAGNDSESLLHWYQSQDAEIFLKAEG-----FKYPASGMFSF---------VPNYDGDFFPKPF- 314

  Fly   336 VEEPIR--SYQNDDFMKVPIITGMTKDEFVGPALSILQSP--TLLSAL-------NENFESLAPV 389
              :.:|  :.:.|..:.|....|:..:||. |.   .:||  .|.:||       .|.....|..
 Worm   315 --DELRKEAPKLDAIVSVAEYEGLGFEEFY-PG---QKSPQEVLTAALGPEVVRNREEVVKKAVE 373

  Fly   390 FFMYNTSDARACNISQEL----RNHYFPDKLIDANRSLEALSNLYSDALTGFGIHRFVHLAARST 450
            .::.|..|.....|.::|    .::||...:.|..|||....|
 Worm   374 AYLENIEDKSGEKIGKKLVEIFGDYYFSVGVFDTVRSLAKYGN---------------------- 416

  Fly   451 KVYYYRFSYQGARSHIYYPEDAPYGVVHHD-DLMYLFVEPSISRMFTEDDDEFRMVDIMVRMFSA 514
            .||...|:|....:.|.:.|:.|:....|. |:.|:..: .|.....||.   :::|:|....:.
 Worm   417 NVYLSSFNYFNPETPIMFGENRPFNAASHGCDIRYILGD-GIGEFSKEDR---KVMDMMGTYLTN 477

  Fly   515 FAYKGDPN-KPTDLALRDIRWRPFSFKK--RYY-LDIGKHITLEENLNAENYEI 564
            ||..|:|| |..     .|.|..:|...  ||: :|..| ..:.:|.....|:|
 Worm   478 FAKYGNPNGKGV-----SIPWEKYSLDNPGRYFKIDYPK-CEMADNFLDGRYKI 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	41..565	CDD:278561	160/574 (28%)
cest-35.1	NP_504400.1	COesterase	14..516	CDD:278561	157/563 (28%)
		Aes	<106..>214	CDD:223730	47/117 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157244
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.750