Protein Alignment CG4382 and cest-6

DIOPT Version :10

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_501070.1
• Gene: cest-6 / 177459
• WormBaseID: WBGene00020688
• Length: 583
• Species: Caenorhabditis elegans
• Alignment Length: 574
• Identity: 139/574 - (24%)
• Similarity: 222/574 - (38%)
• Gaps: 142/574 - (24%)

  Fly    45 VITTALGKIRGTILPSQSGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCPQL 109
            ||||:||.|.|    :|.| ::..|:.||:||||:.:||||.|...|:|...|:||..||.|...
 Worm    25 VITTSLGSING----NQIG-SYQTFKKIPFAKPPIGKLRFQKPMAAEKWEGILNATEYGPACMSN 84

  Fly   110 GLVSGD----VSEDCLRVNIYTKELPSESQPNVRRPVIVFIHPGGFYSLSGQSKNFAGPQY---- 166
            ...|..    :.||||.:||:|.:....|:   ...|:.::|.|   .|...|......:|
 Worm    85 SSTSKSPQKWIDEDCLHINIFTTDTCLSSK---NCSVVFYVHGG---ELVYDSAVMFEDKYLFDT 143

  Fly   167 FMNRRLVLVTFNYRLGSLG-FLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPSSITLLGYG 230
            |.:|.::||...:|||... |:......||.|:.|.|.:..|.:||..|..|||....:|..|:.
 Worm   144 FSSRDVILVIPAFRLGLFSHFVVEDQNVAPNNLALYDILLALEFVKSEIHNFGGSSDRVTAFGHS 208

  Fly   231 AGAMAVTLHMVSPMS--------RGLFHKAIVMSGAVTGQWSLPDHQMDVATKQATLLHCHT--- 284
            .|.     |:||.|:        ...|.:.|.||.  ...|...:.:::...:.....:|..
 Worm   209 YGG-----HVVSVMAFSTEINTDLSYFQRVICMSS--VNVWDSLEFEIEKTMRFIQYANCSVPQD 266

  Fly   285 --------ENVTEMMDCLKGKHYLEFANTLPKMFEFDRNNP----LILWKPVIEPDFGQERFLVE 337
                    |..:.||:||:....:|... :.:..| |..:|    |:|.:|:|:....|:.:  |
 Worm   267 LKSRMTSFEQDSYMMECLQDIDSMELLR-IQRSLE-DEGHPIYSGLVLREPLIQNVLVQDFY--E 327

  Fly   338 EPIRSYQNDDFMKVPIITGMTKDEFVGPALSILQSPTLLSALNENFESLAPVFFMYNTSDARACN 402
            :|         ..:|.:||.|..|.                  :.|.:...:.......:.:.|:
 Worm   328 KP---------KNIPTLTGCTYKEL------------------DKFHAYHNIVETLGYENYKECD 365

  Fly   403 ISQELRNHYFPDKLIDANRSLEALSNLYSDALTGFGIHRFVHLAARSTKV----------YYYRF 457
                       ||..|..:......|.::|..  |||     ||....||          |:|.:
 Worm   366 -----------DKYRDDRKYGRFDLNKHADET--FGI-----LAQTKLKVDKQLDKGIPTYFYEY 412

  Fly   458 SYQGARSHIYYPEDAPYGVVHHDDLMYLFVEPSISRMFTEDDDEFRMVDIMVRMFSAFAYKGDPN 522
            ||             |....|.|||.|:..    ...|.:|::|..:......||..|...|:|.
 Worm   413 SY-------------PKHPSHTDDLSYIMG----VHAFEKDENEIHLAKSYQEMFMNFVKFGEPG 460

  Fly   523 KPTDLALRDIRWRPFSFKKRYYLDI------GKHITLEENLNAENYEIW-KRLF 569
            ...:::         :|:...|.:.      |:..:::.|...|..:.| |.:|
 Worm   461 GGFEMS---------TFENSSYFNFYWNETTGEKSSMKTNFEKEIIKYWLKDMF 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	42..565	CDD:395084	136/567 (24%)
cest-6	NP_501070.1	alpha/beta hydrolases	25..500	CDD:473884	136/567 (24%)