Protein Alignment CG4382 and cest-4

DIOPT Version :9

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_501043.1
• Gene: cest-4 / 177445
• WormBaseID: WBGene00015930
• Length: 592
• Species: Caenorhabditis elegans
• Alignment Length: 591
• Identity: 146/591 - (24%)
• Similarity: 233/591 - (39%)
• Gaps: 178/591 - (30%)

  Fly    45 VITTALGKIRGTILPSQSGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCPQL 109
            :::|:||:|.|    .|.| :|:.|:.||.||||:.:||||.|||.|:|....:|...||.|...
 Worm    28 IVSTSLGQIDG----DQIG-SFHLFKHIPLAKPPIGKLRFQKPEPPEKWTGVRNAKAYGPACISN 87

  Fly   110 GLVSGD----VSEDCLRVNIYTKELPSESQPNVRRPVIVFIHPGGFYSLSGQSKNFAGPQY---- 166
            ..||..    :.||||.:||:|.:...:|:...   |:.:.|.||   |...|.......|
 Worm    88 SSVSTSPQKWIDEDCLHINIFTSDKCLKSKDCA---VVTYFHGGG---LMYDSAVMFNDTYLLGT 146

  Fly   167 FMNRRLVLVTFNYRLGSLG-FLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPSSITLLGYG 230
            |:|:.:::....:|||... |:......||.|:.|.|.:..:.:||..|..|||:....|::|:.
 Worm   147 FVNQDVIIAIPAFRLGIFSHFVVEDQSIAPTNLALYDILLGVEFVKNEIHNFGGNNQKNTIMGHS 211

  Fly   231 AGAMAVTL--------HMVSPMSRGLFHKAIVMSGAVTGQWSLPDHQMDVATKQATLLHCHTENV 287
            .|...|.:        |.:|     ||.::|.||..  ..:...:.|:....:.|....|...::
 Worm   212 YGGSIVNILTFSSKINHDLS-----LFQQSICMSSG--HDFETLEIQIQKTNRFAKHAGCTVPSI 269

  Fly   288 TE-----------MMDCLKGKHYLEFANTLPKMFEFDRNNP----LILWKPVIEPDFGQERFLVE 337
            .|           .|.||:.|..||... :.::.| |...|    |:..:|:|:          |
 Worm   270 IEKKMTTRQSDLYRMKCLQNKDALELLR-VQRLLE-DEGYPTYGYLVQREPLIQ----------E 322

  Fly   338 EPIRSYQNDDFM----KVPIITGMTKDEF--------VGPALSILQSPTLLSALNENFESLAPVF 390
            .|   ||  :||    |:|::||.|:.|.        :|.||              .||:...|:
 Worm   323 IP---YQ--EFMKSPKKIPMLTGCTRYEMDHSPAPKPIGQAL--------------GFENPEEVY 368

  Fly   391 FMYNTSDARACNISQELRNHYFPDKLIDANRSLEALSNLYSDALTGFGIH-------------RF 442
            ..:...                                 :.|.:..||.|             |.
 Worm   369 MKFRKD---------------------------------WDDEVYEFGNHSDETQAIMVQVRVRV 400

  Fly   443 VHLAARSTKVYYYRFSYQGARSHIYYPEDAPYGVVHHDDLMYLFVEPSISRMFTEDDDEFRMVDI 507
            .:|.:::...|.|.::|             |....|.|||.||.   .:.| |.:|::|..:..:
 Worm   401 NNLLSKNVPAYLYEYTY-------------PKHARHTDDLFYLM---GVHR-FEKDENEIELGKV 448

  Fly   508 MVRMFSAFAYKGDPNKPTDLA------LRDIRW------RP---FSFKKR---YYL----DIGKH 550
            ...:|..||..|||.:..:||      ..::.|      ||   ..|:::   |:|    :..||
 Worm   449 YETIFMNFAKFGDPKEGFELANAENESYYEVYWDGETGERPQMKTKFEEKIINYWLKDMVEYDKH 513

  Fly   551 ITLEEN 556
            ||..:|
 Worm   514 ITELKN 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	41..565	CDD:278561	146/591 (25%)
cest-4	NP_501043.1	Abhydrolase	28..503	CDD:389770	139/573 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810