Protein Alignment CG4382 and cest-5.1

DIOPT Version :10

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_501022.3
• Gene: cest-5.1 / 177429
• WormBaseID: WBGene00015279
• Length: 580
• Species: Caenorhabditis elegans
• Alignment Length: 555
• Identity: 146/555 - (26%)
• Similarity: 229/555 - (41%)
• Gaps: 127/555 - (22%)

  Fly    44 LVITTALGKIRGTILPSQSGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKC-- 106
            |:|.|:.|.:.|    ::.| :::.|:.||:|||||..||||.||...:|.....|...||.|
 Worm    19 LIIHTSFGHLEG----AEIG-DYHLFKKIPFAKPPVGNLRFQKPEAAGKWDGIRSAIEYGPACMS 78

  Fly   107 -------PQLGLVSGDVSEDCLRVNIYTKELPSESQPNVRRPVIVFIHPGGF-YSLSGQSKNFAG 163
                   ||..     |.||||.|||:|.:...:|:   ...:.|:||.||. |..:....:...
 Worm    79 NSSKTKSPQKW-----VDEDCLHVNIFTSKKCLKSR---NCAIAVYIHGGGLTYDSAVMFNDTVL 135

  Fly   164 PQYFMNRRLVLVTFNYRLGSLG-FLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPSSITLL 227
            ...|:.|.::||...:|||... |.......||.|:.|.|....|.:||..|..|||:...|||.
 Worm   136 LDTFVKRDVILVIPGFRLGIFSHFTVHNQNVAPNNLALYDITLALEFVKSEIHSFGGNSQKITLF 200

  Fly   228 G--YGAGAMAVTLHMVSPMSR--GLFHKAIVMSGAVTGQWSLPDHQMDVATKQATLLHC------ 282
            |  || |.:|..:...|.::|  .||.:||||||....: .|.|| ::...:.....:|
 Worm   201 GHSYG-GGLASMMTFSSEINRDLSLFQQAIVMSGGFYFE-ELKDH-IEGTKRFVEYANCSVPLKL 262

  Fly   283 -----HTENVTEMMDCLKGKHYLEFANTLPKMFEFDRNNP----LILWKPVIEPDFGQERFLVEE 338
                 .::....||.||:....:|... :.::.| |:..|    :||.:|:. ||.  ::|   |
 Worm   263 ERKMERSQQEMYMMKCLQKLSGMELLR-IQRLLE-DKGYPDFGGVILREPLF-PDV--KKF---E 319

  Fly   339 PIRSYQNDDFMKVPIITGMTKDEFVGPALSILQSPTLLSALNENFESLAPVFFMY-NTSDARACN 402
            .::|.:|     :|::||.|..||                   :.||:...|..| ...:...|:
 Worm   320 LLKSPKN-----IPMLTGCTNLEF-------------------DHESIKVPFGKYLEFENPDECD 360

  Fly   403 ISQELRNHYFPDKLIDANRSLEALSNLYSDALTGFGIH---RFVHLAARSTKVYYYRFSYQGARS 464
              ::.||        |....:|...| ::|...|..:.   :..:|...:...|.|.::|
 Worm   361 --EKYRN--------DVESGVENRGN-HTDKTQGIILPLKLQINNLLENNVTAYLYEYTY----- 409

  Fly   465 HIYYPEDAPYGVVHHDDLMYLFVEPSISRMFTEDDDEFRMVDIMVRMFSAFAYKGDP------NK 523
                    |....|.|||.|:..    ...|.:|::|..:..:...|...|...|:|      ::
 Worm   410 --------PKHGRHTDDLSYIMG----VHAFEKDENEVHLEQVYKDMVINFIKLGEPGMGFEKSE 462

  Fly   524 PTDLALRDIRW------RPFSFKKRYYLDIGKHIT 552
            ..:....||.|      ||   :.|.|.:  |.:|
 Worm   463 QNESTYFDIYWNETTGERP---RMRKYFE--KEVT 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	42..565	CDD:395084	146/555 (26%)
cest-5.1	NP_501022.3	alpha/beta hydrolases	17..495	CDD:473884	146/555 (26%)