Protein Alignment CG4382 and cest-5.2

DIOPT Version :9

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_501021.3
• Gene: cest-5.2 / 177428
• WormBaseID: WBGene00015284
• Length: 583
• Species: Caenorhabditis elegans
• Alignment Length: 585
• Identity: 154/585 - (26%)
• Similarity: 230/585 - (39%)
• Gaps: 153/585 - (26%)

  Fly    45 VITTALGKIRGTILPSQSGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKC--- 106
            :|.|:||::.|    .|||: :..||.||:||||:..||||.||..|:|....:||..||.|
 Worm    23 IIKTSLGRLEG----KQSGK-YQLFRRIPFAKPPIGTLRFQKPESAEKWNGVWNATEYGPACMSN 82

  Fly   107 ------PQLGLVSGDVSEDCLRVNIYTKELPSESQPNVRRPVIVFIHPGG--FYSLSGQSKNFAG 163
                  ||..     |.||||.|||:|.:...:|:...   |:|:||.|.  |.|....:..|.
 Worm    83 STWTQSPQKW-----VDEDCLHVNIFTSDKCLKSKDCA---VVVYIHGGEIVFDSAVMFNDTFL- 138

  Fly   164 PQYFMNRRLVLVTFNYRLGSLG-FLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPSSITLL 227
            .:.|:.:.::||...:|||... |.......||.|:.|.|.:....:||..|..||||...|||.
 Worm   139 LESFVKQDVILVIPAFRLGIFSHFTVHDQNIAPNNLALYDIILAQEFVKSEIHNFGGDIQKITLF 203

  Fly   228 G--YGAGAMAVTLHMVSPMSR--GLFHKAIVMSG-----AVTGQWSLPDHQM-----DVATKQAT 278
            |  || |.:|..:...|.:::  .||.:.||||.     .:..|....|..:     .|.|..|.
 Worm   204 GHSYG-GTIASMMAFSSEINQDLSLFQRIIVMSANQYFDTLEEQIERSDRVVKHAGCSVPTNLAR 267

  Fly   279 LLHCHTENVTEMMDCLK---GKHYLEFANTLPKMFEFDRNNPLILWKPVIEPDFGQERFLVEEPI 340
            .:: .::....||.||:   |...|....:|.:....|..| |:|..|:. ||......| |.|
 Worm   268 KMN-RSQKEKYMMKCLQKLSGMELLSVQRSLEEAGYPDIGN-LVLRGPLF-PDVTSLEML-ESP- 327

  Fly   341 RSYQNDDFMKVPIITGMTKDE--------FVGPALSILQSPTLLSALNENFESLAPVFFMYNTSD 397
                    ..:|::.|.||.|        |:|.... |::|.   ..:|.:.
 Worm   328 --------KMIPMLAGCTKFESDDEDETHFIGKHFG-LENPI---ECDEKYR------------- 367

  Fly   398 ARACNISQELRNHYFP-DKLIDANRSLEALSNLYSDALTGFGIHRFVHLAARSTKVYYYRFSYQG 461
                   ::|.|..|. ....|..:::...:.|..|.|...|:           ..|.|.|:|
 Worm   368 -------KDLENGIFDRQNHSDKTQAIMVPTKLRVDQLRKHGV-----------PAYLYEFTY-- 412

  Fly   462 ARSHIYYPEDAPYGVVHHDDLMYLF-VEPSISRMFTEDDDEFRMVDIMVRMFSAFAYKGDPN--- 522
                       |....|.|||.|:. :.|     |.:|::|..:..:...|...|...|:|.
 Worm   413 -----------PKHAFHTDDLYYIMGIHP-----FEKDENEEHLEKVYRNMLINFIKFGEPGMGF 461

  Fly   523 KPTDL---ALRDIRWRPFS-----FKKRYYLDIGKHITLEENLNAENYEIWKRLFPLNWRRQTKE 579
            :.:||   ...:|.|...:     .:||:          |||:.  ||          |.::..|
 Worm   462 EMSDLNESTYFEIYWNETTGQKPRMRKRF----------EENIT--NY----------WLKEMME 504

  Fly   580  579
             Worm   505  504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	41..565	CDD:278561	152/569 (27%)
cest-5.2	NP_501021.3	Abhydrolase	23..498	CDD:389770	152/577 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156900
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740