Protein Alignment CG4382 and Nlgn3

DIOPT Version :10

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_599163.2
• Gene: Nlgn3 / 171297
• RGDID: 621119
• Length: 848
• Species: Rattus norvegicus
• Alignment Length: 639
• Identity: 167/639 - (26%)
• Similarity: 269/639 - (42%)
• Gaps: 167/639 - (26%)

  Fly    46 ITTALGKIRG--TILPSQSGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCPQ 108
            :.|..||:||  ..|||:.......:.|:|||.||:...||.||||...|....:||...|.|||
  Rat    44 VNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQ 108

  Fly   109 ------------------LGLVS---GDVSEDCLRVNIYTKELPSES----------QPNVR--- 139
                              |.:|:   .:.:||||.:|:|   :|:|.          :||.:
  Rat   109 NIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVY---VPTEDVKRISKECARKPNKKICR 170

  Fly   140 -----------------------------RPVIVFIHPGGFYSLSGQSKNFAGPQYFMNRRLVLV 175
                                         :||:|:|| ||.| :.|......|........::::
  Rat   171 KGGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIH-GGSY-MEGTGNMIDGSVLASYGNVIVI 233

  Fly   176 TFNYRLGSLGFLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPSSITLLGYGAGAMAVTLHM 240
            |.|||:|.||||:||.:.|.||.||.||:|.||||..:|:.|||||..||:.|.|.||..|:|..
  Rat   234 TLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLT 298

  Fly   241 VSPMSRGLFHKAIVMSGAVTGQWSLPDHQMDVATKQATLLHCHTENVTEMMDCLKGKHYLEFA-- 303
            :|..|.|||.:||:.||:....|::....:...:..|..:.|:..:..:|:|||:.|...|..
  Rat   299 LSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQ 363

  Fly   304 NTLPKMFEFDRNNPLILWKPVIEPDFGQERFLVEEPIRSYQNDDFMKVPIITGMTKDEFVGPALS 368
            :..|..:.       :.:.|||:.|     .:.::|....:..:|:...|:.|:.:    |..|.
  Rat   364 DIQPARYH-------VAFGPVIDGD-----VIPDDPEILMEQGEFLNYDIMLGVNQ----GEGLK 412

  Fly   369 ILQSPTLLSALNENFESLAPVFFMYNTSDARACNISQELRNHYFPDKLI------DANRSLEALS 427
            .::      .:.:..:.::...|.|:.|:              |.|.|.      |..|  |.:.
  Rat   413 FVE------GVVDPEDGVSGTDFDYSVSN--------------FVDNLYGYPEGKDTLR--ETIK 455

  Fly   428 NLYSD---------------ALTGFGIHRFVH-------LAAR-STKVYYYRFSYQGARSHIYYP 469
            .:|:|               ||  |..|::|.       |.|| .:..|:|.| |...:| :..|
  Rat   456 FMYTDWADRDNPETRRKTLVAL--FTDHQWVEPSVVTADLHARYGSPTYFYAF-YHHCQS-LMKP 516

  Fly   470 --EDAPYGVVHHDDLMYLFVEPSISRM------FTEDDDEFRMVDIMVRMFSAFAYKGDPNKPTD 526
              .||.:|    |::.|:|..|.:...      |:::|  ..:..:::..::.||..||||||..
  Rat   517 AWSDAAHG----DEVPYVFGVPMVGPTDLFPCNFSKND--VMLSAVVMTYWTNFAKTGDPNKPVP 575

  Fly   527 L----------ALRDIRWRPFSFKKRYYLDIGKHITLEENLNAENYEIWKRLFP 570
            .          ...::.|..::.:.:.||.||....:.::..|.....||.|.|
  Rat   576 QDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVP 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	42..565	CDD:395084	163/632 (26%)
Nlgn3	NP_599163.2	COesterase	40..624	CDD:395084	163/632 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	169..195		0/25 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	645..691