Protein Alignment CG4382 and Nlgn1

DIOPT Version :10

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: XP_038957495.1
• Gene: Nlgn1 / 116647
• RGDID: 621117
• Length: 863
• Species: Rattus norvegicus
• Alignment Length: 694
• Identity: 185/694 - (26%)
• Similarity: 280/694 - (40%)
• Gaps: 178/694 - (25%)

  Fly     1 MWR---LC------GFVLLLCGLASGQNSDEDLSKAIPDEEDPIGSNKELSDLVITTALGKIRGT 56
            :||   .|      |..|.||.|.....:...||:.: |:.||:          :||..|||||
  Rat    12 VWRAMMACVVHRGSGAPLTLCLLGCLLQTFHVLSQKL-DDVDPL----------VTTNFGKIRG- 64

  Fly    57 ILPSQSGRNFYA----FRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCPQ--------- 108
             :..:.......    |.|:|||.||....|||||||...|.|..:||...|.|||
  Rat    65 -IKKELNNEILGPVIQFLGVPYAAPPTGEHRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPE 128

  Fly   109 ----------LGLVSG---DVSEDCLRVNIY----------------------------TKELPS 132
                      |.:||.   |.|||||.:|||                            ||....
  Rat   129 VMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDVKRISKECARKPGKKICRKGGPLTKTQTD 193

  Fly   133 ESQPNVR------------RPVIVFIHPGGFYSLSGQSKNFAGPQYFMNRRLVLVTFNYRLGSLG 185
            :...|.|            :||:|:|| ||.| :.|....:.|........::::|.|||||.||
  Rat   194 DLGDNDRAEDEDIRDSGGPKPVMVYIH-GGSY-MEGTGNLYDGSVLASYGNVIVITVNYRLGVLG 256

  Fly   186 FLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPSSITLLGYGAGAMAVTLHMVSPMS----- 245
            ||:||.:.|.||.||.|.:|.|||...:|..|||||..||:.|.|||...|.|..:|..|
  Rat   257 FLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRW 321

  Fly   246 ----RGLFHKAIVMSGAVTGQWSLPDHQMDVATKQATLLHCHTENVTEMMDCLKGKHYLEFA--N 304
                :|||.:||..||.....|::.......|...||.:.|:..:..|:::||:.|.|.|..  :
  Rat   322 SNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARILATKVGCNVSDTVELVECLQKKPYKELVDQD 386

  Fly   305 TLPKMFEFDRNNPLILWKPVIEPDFGQERFLVEEPIRSYQNDDFMKVPIITGMTKDEFVGPALSI 369
            ..|..:.       |.:.|||:.|     .:.::|....:..:|:...|:.|:.:.|.:....:|
  Rat   387 VQPARYH-------IAFGPVIDGD-----VIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENI 439

  Fly   370 LQSPTLLSALNENFESLAPVFFMYNTSDARACNISQELRNHY-FPDKLIDANRSLEALSNLYSD- 432
            :.|...:||.:.:|.                  :|..:.|.| :|:.. |..|  |.:..:|:|
  Rat   440 VDSDDGVSASDFDFA------------------VSNFVDNLYGYPEGK-DVLR--ETIKFMYTDW 483

  Fly   433 ------------ALTGFGIHRFVHLAARS--------TKVYYYRFSYQGARSHIYYPEDAPYGVV 477
                        .|..|..|::|..|..:        :..|:|.|.:......:....||.:|
  Rat   484 ADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSPTYFYAFYHHCQTDQVPAWADAAHG-- 546

  Fly   478 HHDDLMYLFVEPSISRM------FTEDDDEFRMVDIMVRMFSAFAYKGDPNKPTDL--------- 527
              |::.|:...|.|...      |:::|  ..:..:::..::.||..||||:|...
  Rat   547 --DEVPYVLGIPMIGPTELFPCNFSKND--VMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKP 607

  Fly   528 -ALRDIRWRPFSFKKRYYLDIGKHITLEENLNAENYEIWKRLFP 570
             ...::.|..:|.|.:.||.||....::|:..|....:|..|.|
  Rat   608 NRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRANKVNLWLELVP 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	42..565	CDD:395084	169/637 (27%)
Nlgn1	XP_038957495.1	COesterase	52..646	CDD:395084	171/646 (26%)