Protein Alignment CG4382 and Ces1d

DIOPT Version :9

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_579829.3
• Gene: Ces1d / 113902
• RGDID: 70896
• Length: 565
• Species: Rattus norvegicus
• Alignment Length: 595
• Identity: 169/595 - (28%)
• Similarity: 256/595 - (43%)
• Gaps: 123/595 - (20%)

  Fly    45 VITTALGKIRGTILPSQS-GRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCPQ 108
            |:.|..||:.|..:..:. .:....|.|||:||||:..|||.||:|.|.|....:.|...|.|.|
  Rat    25 VVNTVKGKVLGKYVNLEGFAQPVAVFLGIPFAKPPLGSLRFAPPQPAEPWNFVKNTTSYPPMCSQ 89

  Fly   109 LGLVSGDV----------------SEDCLRVNIYTKELPSESQPNVRRPVIVFIHPGGFYSLSGQ 157
             ..|.|.|                |||||.:|:||   |::...|.|.||:|:||.||.  :.|.
  Rat    90 -DAVGGQVLSELFTNRKENIPLQFSEDCLYLNVYT---PADLTKNSRLPVMVWIHGGGL--VVGG 148

  Fly   158 SKNFAGPQYFMNRRLVLVTFNYRLGSLGFLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPS 222
            :..:.|.....:..:|:||..||||..||.:||...:.||.|..|||..|.||:.:|:.|||:|.
  Rat   149 ASTYDGQVLSAHENVVVVTIQYRLGIWGFFSTGDEHSQGNWGHLDQVAALHWVQDNIANFGGNPG 213

  Fly   223 SITLLGYGAGAMAVTLHMVSPMSRGLFHKAIVMSGAVTGQWSLPDHQMDVATKQATLLHCHTENV 287
            |:|:.|..||..:|:..::||:::.|||:||..||.|.....:......:|...|||..|.|...
  Rat   214 SVTIFGESAGGFSVSALVLSPLAKNLFHRAISESGVVLTSALITTDSKPIANLIATLSGCKTTTS 278

  Fly   288 TEMMDCLKGKHYLEFANTLPK--MFEFDRNNPLILWKP-------------VIEPDFGQERFLVE 337
            ..|:.||:.|...|...|..|  :|:.|     :|..|             |:.|...:| .|.|
  Rat   279 AVMVHCLRQKTEDELLETSLKLNLFKLD-----LLGNPKESYPFLPTVIDGVVLPKTPEE-ILTE 337

  Fly   338 EPIRSYQNDDFMKVPIITGMTKDEF-------VGPALS--ILQSPTLLSALNENFESLAPVFFMY 393
            :        .|..||.|.|:.|.||       :|..||  .|...|..|.|.:::.:|
  Rat   338 K--------SFNTVPYIVGINKQEFGWIIPTLMGYPLSEGKLDQKTAKSLLWKSYPTL------- 387

  Fly   394 NTSDARACNISQEL----RNHYFPDKLIDANRSLEALSNLYSDALTGFGIHRFVHLAARSTK--- 451
                    .||:::    ...||......|.|. :...:|.:|.:  ||:...  :.:||.:
  Rat   388 --------KISEKMIPVVAEKYFGGTDDPAKRK-DLFQDLVADVM--FGVPSV--MVSRSHRDAG 439

  Fly   452 --VYYYRFSYQGARSHIYYPEDAPYGVV--HHDDLMYLFVEPSISRMFTED---DDEFRMVDIMV 509
              .:.|.|.|:.:    :.....|..|:  |.|:|..:|..|     |.:|   ::|..:..:::
  Rat   440 APTFMYEFEYRPS----FVSAMRPKTVIGDHGDELFSVFGSP-----FLKDGASEEETNLSKMVM 495

  Fly   510 RMFSAFAYKGDPN---KPTDLALRDIRWRPFSFKKRYYLDIGKHITLEENLNAENYEIWKRL--- 568
            :.::.||..|.||   .|        .|..:. :|..||.||......:.|..:....|..|
  Rat   496 KYWANFARNGSPNGGGLP--------HWPEYD-QKEGYLKIGASTQAAQRLKDKEVAFWSELRAK 551

  Fly   569 ----FPLNWR 574
                .|.:|:
  Rat   552 EAAEEPSHWK 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	41..565	CDD:278561	165/577 (29%)
Ces1d	NP_579829.3	COesterase	24..545	CDD:278561	165/577 (29%)
		Aes	<121..>239	CDD:223730	47/122 (39%)
		Prevents secretion from ER. /evidence=ECO:0000255	562..565		169/595 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336166
Domainoid	1	1.000	232	1.000	Domainoid score	I2325
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	232	1.000	Inparanoid score	I3341
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.000