Protein Alignment CG4382 and Ces1d

DIOPT Version :10

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_444430.2
• Gene: Ces1d / 104158
• MGIID: 2148202
• Length: 565
• Species: Mus musculus
• Alignment Length: 586
• Identity: 169/586 - (28%)
• Similarity: 251/586 - (42%)
• Gaps: 124/586 - (21%)

  Fly    45 VITTALGKIRGTILPSQSGRNFYA-FRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCPQ 108
            |:.|..||:.|..:..:......| |.|:|:||||:..|||.||:|.|.|....:.|...|.|.|
Mouse    25 VVNTVKGKVLGKYVNLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTSYPPMCSQ 89

  Fly   109 LGLVSGDV----------------SEDCLRVNIYTKELPSESQPNVRRPVIVFIHPGGFYSLSGQ 157
             ..|.|.|                |||||.:||||   |::...|.|.||:|:||.||.  :.|.
Mouse    90 -DAVGGQVLSELFTNRKENIPLQFSEDCLYLNIYT---PADLTKNSRLPVMVWIHGGGL--VVGG 148

  Fly   158 SKNFAGPQYFMNRRLVLVTFNYRLGSLGFLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPS 222
            :..:.|.....:..:|:||..||||..||.:||...:.||.|..|||..||||:.:|:.|||:|.
Mouse   149 ASTYDGLALSAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIANFGGNPG 213

  Fly   223 SITLLGYGAGAMAVTLHMVSPMSRGLFHKAIVMSGAVTGQWSLPDHQMDVATKQATLLHCHTENV 287
            |:|:.|..||..:|::.::||:::.|||:||..||.......:......:|...|||..|.|...
Mouse   214 SVTIFGESAGGFSVSVLVLSPLAKNLFHRAISESGVSLTAALITTDVKPIAGLVATLSGCKTTTS 278

  Fly   288 TEMMDCLKGKHYLEFANTLPK--MFEFDRNNPLILWKP-------------VIEPDFGQERFLVE 337
            ..|:.||:.|...|...|..|  :|:.|     :|..|             |:.|. ..|..|.|
Mouse   279 AVMVHCLRQKTEDELLETSLKLNLFKLD-----LLGNPKESYPFLPTVIDGVVLPK-APEEILAE 337

  Fly   338 EPIRSYQNDDFMKVPIITGMTKDEF--VGPAL-------SILQSPTLLSALNENFESLAPVFFMY 393
            :        .|..||.|.|:.|.||  :.|.|       ..|...|..|.|.:::.:|
Mouse   338 K--------SFSTVPYIVGINKQEFGWIIPTLMGYPLAEGKLDQKTANSLLWKSYPTL------- 387

  Fly   394 NTSDARACNISQELRNHYFP---DKLIDANRSLEALSNLYSDALTG--FGI--------HRFVHL 445
                    .||:.:    .|   :|.:.....|....:|:.|.:..  ||:        ||.
Mouse   388 --------KISENM----IPVVAEKYLGGTDDLTKKKDLFQDLMADVVFGVPSVIVSRSHRD--- 437

  Fly   446 AARSTKVYYYRFSYQGARSHIYYPEDAPYGVV--HHDDLMYLFVEPSISRMFTED---DDEFRMV 505
            |..||  |.|.|.|:.:    :.....|..|:  |.|::..:|..|     |.:|   ::|..:.
Mouse   438 AGAST--YMYEFEYRPS----FVSAMRPKAVIGDHGDEIFSVFGSP-----FLKDGASEEETNLS 491

  Fly   506 DIMVRMFSAFAYKGDPN---KPTDLALRDIRWRPFSFKKRYYLDIGKHITLEENLNAENYEIWKR 567
            .::::.::.||..|:||   .|        .|..:. :|..||.||......:.|..:....|..
Mouse   492 KMVMKFWANFARNGNPNGGGLP--------HWPEYD-QKEGYLKIGASTQAAQRLKDKEVSFWAE 547

  Fly   568 L 568
            |
Mouse   548 L 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	42..565	CDD:395084	167/581 (29%)
Ces1d	NP_444430.2	COesterase	22..545	CDD:395084	167/581 (29%)
		Prevents secretion from ER. /evidence=ECO:0000255	562..565