Protein Alignment CG4382 and nlgn4xb

DIOPT Version :10

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_001159809.1
• Gene: nlgn4xb / 100147967
• ZFINID: ZDB-GENE-100309-1
• Length: 795
• Species: Danio rerio
• Alignment Length: 622
• Identity: 176/622 - (28%)
• Similarity: 269/622 - (43%)
• Gaps: 115/622 - (18%)

  Fly     5 CGFVLLLCGLASGQNSDEDLSKAIPDEEDPIGSNKELSDLVITTALGKIRG--TILPSQSGRNFY 67
            |||.|.|.                          ::...:.:||..||:||  ..|||:......
Zfish    10 CGFTLALA--------------------------QQTQFITVTTNYGKLRGLRVALPSEILGPVE 48

  Fly    68 AFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCPQ-------------------LGLVS 113
            .|.|:|||..|....|||.|||...|....:||...|.|||                   |..|:
Zfish    49 QFLGVPYAMAPTGERRFQAPEPPLSWPGIRNATQFAPVCPQFLEDRLLLTDMLPVWFTANLDTVA 113

  Fly   114 ---GDVSEDCLRVNIY--TKELPSESQPNV-RRPVIVFIHPGGFYSLSGQSKNFAGPQYFMNRRL 172
               .|.|||||.:|||  |:|   |:|.:. .:||:|:|| ||.| :.|......|........:
Zfish   114 TYVHDQSEDCLYLNIYVPTEE---ETQDDAGLKPVMVYIH-GGSY-VEGTGNMIDGSVLASYGNV 173

  Fly   173 VLVTFNYRLGSLGFLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPSSITLLGYGAGAMAVT 237
            ::||.|||||.||||:||.:.|.||.||.||:|.|||||.:|..|.|||..:|:.|.||||..|:
Zfish   174 IVVTVNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWVKENIQSFSGDPERVTIFGSGAGASCVS 238

  Fly   238 LHMVSPMSRGLFHKAIVMSGAVTGQWSLPDHQMDVATKQATLLHCHTENVTEMMDCLKGKHYLEF 302
            |..:|..|..||.|||:.||.....|::...........|..:.|:.::..|:::||:.|:|.|.
Zfish   239 LLTLSHYSEDLFQKAIIHSGTALSSWAVNYQPAKYTRLLAEKVGCNEDDTLELIECLQSKNYKEL 303

  Fly   303 --ANTLPKMFEFDRNNPLILWKPVIEPDFGQERFLVEEPIRSYQNDDFMKVPIITGMTKDE---F 362
              .|..|..:.       |.:.|||:.|     .:.::|....:..:|:...|:.|:.:.|   |
Zfish   304 IEQNITPAKYH-------IAFGPVIDGD-----VIPDDPQILMEQGEFLNYDIMLGVNQGEGYKF 356

  Fly   363 VGPALSILQSPTLLSALNENFESLAPVFFMYNTSDARACNISQELRNHYFPDKLIDANRSL--EA 425
            |.   .||.|...:::.:..|.....|..:|...:.:  :..:|.....:.|.....|..:  :.
Zfish   357 VD---GILDSEDRVTSNDFEFAISEFVDHLYGYPEGK--DTLRETIKFMYTDWADRENPEMRRKT 416

  Fly   426 LSNLYSD------ALTGFGIHRFVHLAARSTKVYYYRFSYQGARSHIYYPEDAPYGVVHHDDLMY 484
            |..|::|      |:....:|     |...:..|:|.| |...:|.:   :.|.....|.|:|.|
Zfish   417 LVALFTDHQWVAPAVATADLH-----AQYGSPTYFYAF-YHHCQSDM---KPAWADSSHGDELPY 472

  Fly   485 LFVEPSISRM------FTEDDDEFRMVDIMVRMFSAFAYKGDPNKPTDL----------ALRDIR 533
            :|..|.|...      |:::|  ..:..:::..::.||..||||:|...          ...::.
Zfish   473 VFGIPMIGPTDLFNCNFSKND--IMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVA 535

  Fly   534 WRPFSFKKRYYLDIGKHITLEENLNAENYEIWKRLFP 570
            |..::.|.:.||.||....:.::..|.....|..|.|
Zfish   536 WSKYNPKDQLYLHIGLKPRVRDHYRATKIAFWLELVP 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	42..565	CDD:395084	168/578 (29%)
nlgn4xb	NP_001159809.1	COesterase	24..567	CDD:395084	168/575 (29%)