Protein Alignment CG4382 and nlgn2b

DIOPT Version :10

• Sequence 1: NP_609301.2
• Gene: CG4382 / 34279
• FlyBaseID: FBgn0032132
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_001159808.1
• Gene: nlgn2b / 100002407
• ZFINID: ZDB-GENE-090918-3
• Length: 860
• Species: Danio rerio
• Alignment Length: 664
• Identity: 189/664 - (28%)
• Similarity: 280/664 - (42%)
• Gaps: 168/664 - (25%)

  Fly     1 MWRLCGFVLLLCGLASGQNSDEDLSKAIPDEEDPIGSNKELSDLVITTALGKIRGT-------IL 58
            :| |.|..|.| .|:|.|.:|...:|      .|          ::||..||:||.       ||
Zfish    27 VW-LLGLALRL-ALSSCQRADLTTAK------HP----------MVTTGYGKLRGVRKELNNEIL 73

  Fly    59 -PSQSGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCPQ-------------- 108
             |.:.      :.|:|||.|||...||||||....|.:..:||...|.|||
Zfish    74 GPVEQ------YLGVPYATPPVGERRFQPPEAPGSWQEIRNATQFAPVCPQNIHGVLPEIMLPVW 132

  Fly   109 ----LGLVSGDV---SEDCLRVNIYTKELPSESQP----------------NVR----RPVIVFI 146
                |...:..|   |||||.:|:|   :|:|..|                ::|    :||::||
Zfish   133 FTDNLDAAAAYVQNQSEDCLYLNVY---VPTEDGPLTKKHDESSMNRPRDEDIRDRRKKPVMLFI 194

  Fly   147 HPGGFYSLSGQSKNFAGPQYFMNRRLVLVTFNYRLGSLGFLATGTREAPGNMGLKDQVQLLRWVK 211
            |.|.|  :.|....|..........:::||.|||||.||||::|.:.|.||.||.||:|.|||:.
Zfish   195 HGGSF--MEGTGNMFDASVLAAYGNVIVVTMNYRLGVLGFLSSGDQSAKGNYGLLDQIQALRWLN 257

  Fly   212 LHISRFGGDPSSITLLGYGAGAMAVTLHMVSPMSRGLFHKAIVMSGAVTGQWSLPDHQMDVATKQ 276
            .:|..|||||..||:.|.||||..|.|.::|..|.|||.:||..||:....||:....:......
Zfish   258 ENIGHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQRAIAQSGSAISSWSVNYRPLMYTKIL 322

  Fly   277 ATLLHCHTENVTEMMDCLKGKHYLEFA--NTLPKMFEFDRNNPLILWKPVIEPDFGQERFLVEEP 339
            |..:.|...:..:::|||:.|.|.|..  :..|..:.       |.:.||::.|     .:.::|
Zfish   323 AKKVGCSYSDTADLVDCLRRKSYRELVDQDVQPARYH-------IAFGPVVDGD-----VVPDDP 375

  Fly   340 IRSYQNDDFMKVPIITGMTKDEFVGPALSILQSPTLLSALNENFESLAPVFFMYNTSDARACNIS 404
            ....|..:|:...|:.|:.:    |..|..:..       ||..|.::...|.|        .||
Zfish   376 EILMQQGEFLNYDILLGVNQ----GEGLKFVDD-------NEGEEGISAASFDY--------TIS 421

  Fly   405 QELRNHY-FPDKLIDANRSLEALSNLYSD-------------ALTGFGIHRFVHLAARSTK---- 451
            ..:.|.| :|:.. |..|  |.:..:|:|             .|..|..|::|..|..:.|
Zfish   422 NFVDNLYGYPEGK-DILR--ETIKFMYTDWADRDNGDMRRKTLLALFTDHQWVAPAVATAKLHAE 483

  Fly   452 ----VYYYRFSYQ---GARSHIYYPE--DAPYGVVHHDDLMYLFVEPSISRM------FTEDDDE 501
                ||:|.|.:.   .||     ||  ||.:|    |::.|:|..|.:...      |:::|
Zfish   484 FQSPVYFYTFHHHCQTEAR-----PEWADAAHG----DEIPYVFGVPMVGATELFPCNFSKND-- 537

  Fly   502 FRMVDIMVRMFSAFAYKGDPNKPTDL----------ALRDIRWRPFSFKKRYYLDIGKHITLEEN 556
            ..:..:::..::.||..||||.|...          ...::.|..||.|.:.||.||....:.:|
Zfish   538 IMLSAVVMTYWTNFAKTGDPNIPVPQDTKFIHTKPNRFEEVIWTKFSSKDKQYLHIGLKPRIRDN 602

  Fly   557 LNAENYEIWKRLFP 570
            ..|.....|..|.|
Zfish   603 YRANKVAFWLELVP 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4382	NP_609301.2	COesterase	42..565	CDD:395084	175/616 (28%)
nlgn2b	NP_001159808.1	COesterase	52..611	CDD:395084	176/624 (28%)