DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3841 and Ces2f

DIOPT Version :9

Sequence 1:	NP_001188759.1	Gene:	CG3841 / 34278	FlyBaseID:	FBgn0032131	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_001073334.2	Gene:	Ces2f / 71903	MGIID:	1919153	Length:	561	Species:	Mus musculus

Alignment Length:	564	Identity:	169/564 - (29%)
Similarity:	265/564 - (46%)	Gaps:	77/564 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LLILIGFTTAVTFIGDDPVVELSLGRIQGDTMQSFGNKT-IYAFRGIRYAQSPVGQLRFANPVPE 75
            ||:|:.....:......|:.....|:::|..:.....|. .:.|.||.:|:.|||.||||.|...
Mouse    17 LLVLLLHVKGLDSSEASPIRNTHTGQVRGKFVHLTDIKAGAHNFLGIPFAKPPVGPLRFAPPEAP 81

  Fly    76 TSWGDEVFNATSDSLVCPQ-PGVVSL--------------MSEDCLKINVFTKSFEDK---FPVM 122
            ..|.. |.:.||...:|.| ..:|:|              ||||||.:|::|.:...:   .|||
Mouse    82 EPWSG-VRDGTSQPAMCLQNDDIVNLEGLKIIKMILPPFSMSEDCLYLNIYTPAHAQEGSNLPVM 145

  Fly   123 VYIHGGANVLGSGHSSYEAGPQYLLDQDVVFVAFNYRLGALGFLSTNSSETKGNFGFLDQVMALE 187
            |::|||..|.|.. |.|: |......:|||.|...||||..||.||...:.:||:|||||..||.
Mouse   146 VWLHGGGLVAGMA-SMYD-GSVLAATEDVVVVVTQYRLGIPGFYSTGDEQARGNWGFLDQTAALH 208

  Fly   188 WVRDHISHFGGDPELVTIIGISAGSMAVSLHLASPLSAGLFHRAILMSGSA---TNHFDIDNLFW 249
            ||:.:|::|||:|:.||:.|.|||..:||.|:.||:|.|||||||:.||.|   |...|...:.:
Mouse   209 WVQQNIANFGGNPDSVTLFGQSAGGTSVSFHVLSPVSQGLFHRAIMESGVALLPTIIPDSPEMIF 273

  Fly   250 TRKLARELGCPMYDPTDVVECLRNETWTRIVEVCKAWETYQLVNMKWNYEIDGHFLHNHPTELIK 314
            | |:|...||...:...:|.|||.::...|:.:.||:.....|       :||.||..||.:|:.
Mouse   274 T-KVANLSGCETSNSEALVRCLRGKSEAEILAMSKAFRFMPAV-------VDGKFLPRHPKKLLA 330

  Fly   315 EGNFNKVPLLISFTANE--------FDYNANVHLENQHLLHDFASNFVDYAPELFLYRHDAQIGE 371
            ..:|:.||.:|....:|        |.::..:...|::.|........:   ::.|   .::.|:
Mouse   331 SADFHPVPSIIGVNNDEYGWIIPKIFKFSQTIRKINRNNLKAIMKITTE---QMML---PSECGD 389

  Fly   372 KLKDFYLGDN----TTEINSENIENFGQIFSDAYIGHGVHRLVQLA----SHFTPVYYTRMDYVG 428
            .|.:.||.|.    |.::      .|.::..|..|   :...:|:|    || .|||:....:
Mouse   390 LLIEEYLRDTEDPWTLQM------QFREMIGDFLI---IIPALQVARFQRSH-APVYFYEFQH-- 442

  Fly   429 DQSLSAPLNGENKP--VGVGHADDLHYVLPGYWYGPLMAANDSDVFMMERLTSWFTHFAKTGTPL 491
                .:.|....:|  |...|.|:|:.:...:::|...:....:..:..::..::.:||:.|.|
Mouse   443 ----RSSLLKYFRPWHVKADHGDELYLIFGSFFWGLKFSFTAEEKLLSRKMMKYWANFARYGNP- 502

  Fly   492 NSTDI--WPPCNSTVLKMLYNGVVTQVGSPGYSNRYAVWDKLFP 533
            ||.|:  ||..|...| .|...:...||....:.|...|.|..|
Mouse   503 NSEDLPYWPASNQDDL-YLQLDIHPSVGHALKARRLPFWTKTLP 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3841	NP_001188759.1	COesterase	27..528	CDD:278561	163/542 (30%)
CG3841	NP_001188759.1	Aes	<116..>235	CDD:223730	59/121 (49%)
Ces2f	NP_001073334.2	COesterase	32..540	CDD:395084	163/542 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832764
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	228	1.000	Inparanoid score	I3450
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D233524at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.800