Protein Alignment CG3841 and NCEH1

DIOPT Version :10

• Sequence 1: NP_609300.1
• Gene: CG3841 / 34278
• FlyBaseID: FBgn0032131
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001139748.2
• Gene: NCEH1 / 57552
• HGNCID: 29260
• Length: 416
• Species: Homo sapiens
• Alignment Length: 485
• Identity: 104/485 - (21%)
• Similarity: 162/485 - (33%)
• Gaps: 160/485 - (32%)

  Fly     9 WALLLILIGFTTAVTFIGDDPVVE-----------LSLGRIQGDTMQSFGNKTIYAFRGIRYAQS 62
            |.|:|:      ..||.|...|..           |:|..|    :.|||.|:.::...::
Human    31 WKLMLL------DATFRGAQQVSNLIHYLGLSHHLLALNFI----IVSFGKKSAWSSAQVK---- 81

  Fly    63 PVGQLRFANPVPETSW-GDE--VFNATSDSLVCPQPGVVSLMSEDCLKINVFTKSFEDKFPVMVY 124
                      |.:|.: |.|  ||...      |:|       |:.||.:|            ||
Human    82 ----------VTDTDFDGVEVRVFEGP------PKP-------EEPLKRSV------------VY 111

  Fly   125 IHGGANVLGSGHSSYEAGPQYLL----------DQDVVFVAFNYRLGALGFLSTNSSETKGNFGF 179
            ||||...|.|..:|:....:...          :.:.|.|:..|||
Human   112 IHGGGWALASASASWSPSDEIRYYDELCTAMAEELNAVIVSIEYRL------------------- 157

  Fly   180 LDQVMALEWVRDHI------------SHFGGDPELVTIIGISAGSMAVSLHLASPLSAGLFHRAI 232
            :.:|...|.:.|.:            ..:..||..:.|.|.|||.     :||:.|.     :..
Human   158 VPKVYFPEQIHDVVRATKYFLKPEVLQKYMVDPGRICISGDSAGG-----NLAAALG-----QQF 212

  Fly   233 LMSGSATNHFDIDNLFWTRKLARELGCPMYDPTDVVECLRNETWTRIVEVCKAWETYQLVNMKWN 297
            ....|..|...:..|.:....|.:...|.|.     :.:......|.|.| |.|..|    .|.|
Human   213 TQDASLKNKLKLQALIYPVLQALDFNTPSYQ-----QNVNTPILPRYVMV-KYWVDY----FKGN 267

  Fly   298 YE-IDGHFLHNHPTELIKE-----GNFNKVPLL-ISFTAN-----EFDYNANVHLENQHLLHDFA 350
            |: :....::||.:..::|     ...|...|| .|||.|     :...||.:..|...||...:
Human   268 YDFVQAMIVNNHTSLDVEEAAAVRARLNWTSLLPASFTKNYKPVVQTTGNARIVQELPQLLDARS 332

  Fly   351 SNFV-DYA-----PELFLY--RHDAQIGEKLKD---FYLGDNTTEINSENIENFGQIFSDAYIGH 404
            :..: |.|     |:.::.  .||.     |:|   .|    ...:.|..:|.....|.|.:  |
Human   333 APLIADQAVLQLLPKTYILTCEHDV-----LRDDGIMY----AKRLESAGVEVTLDHFEDGF--H 386

  Fly   405 GVHRLVQLASHFTPVYYTRMDYVG--DQSL 432
            |........::|:....||..|:.  ||:|
Human   387 GCMIFTSWPTNFSVGIRTRNSYIKWLDQNL 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3841	NP_609300.1	COesterase	27..528	CDD:395084	98/467 (21%)
NCEH1	NP_001139748.2	Abhydrolase_3	109..389	CDD:400284	72/341 (21%)