Protein Alignment CG3841 and Aadac

DIOPT Version :10

• Sequence 1: NP_609300.1
• Gene: CG3841 / 34278
• FlyBaseID: FBgn0032131
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_065413.1
• Gene: Aadac / 57300
• RGDID: 631440
• Length: 398
• Species: Rattus norvegicus
• Alignment Length: 456
• Identity: 95/456 - (20%)
• Similarity: 149/456 - (32%)
• Gaps: 144/456 - (31%)

  Fly     1 MPRFFQLTWALLLILIGFTTAVTFIGDDPVVELSLGRIQG-----DTMQSFGNKTIYAFRGIRYA 60
            :|...:..|.   |::|.|  :..:|.|..   |.|.:.|     ||:|.|
  Rat    22 LPDDIEEPWK---IILGNT--LLKLGGDLA---SFGELLGLNHFMDTVQLF-------------- 64

  Fly    61 QSPVGQLRFANPVPETSWGDE-------VFNATSDSLVCPQPGVVSLMSEDCLKINVFTKSFEDK 118
                  :|| ..||.||  ||       .||:....:..|:      .....|:..:|
  Rat    65 ------MRF-QVVPPTS--DENVTVMETDFNSVPVRIYIPK------RKSTTLRRGLF------- 107

  Fly   119 FPVMVYIHGGANVLGSGHSSYEAGPQYLLDQ---------DVVFVAFNYRLGALGFLSTNSSETK 174
                 :||||...|||  ::|     ::.|.         |.|.|:.:|.|.           .|
  Rat   108 -----FIHGGGWCLGS--AAY-----FMYDTLSRRTAHRLDAVVVSTDYGLA-----------PK 149

  Fly   175 GNF--GFLDQVMALEWV--RDHISHFGGDPELVTIIGISAGSMAVSLHLASPLSAGLFHRAILMS 235
            .:|  .|.|...:|.|.  .|.:..:|.||..|.:.|.|||.     :|.:.::     :.||..
  Rat   150 YHFPKQFEDVYHSLRWFLQEDILEKYGVDPRRVGVSGDSAGG-----NLTAAVT-----QQILQD 204

  Fly   236 GSATNHFDIDNLFWTRKLARELGCPMYDPTDVVECLRNETWTRIVEVCKAWETYQLVN------M 294
            ........:..|.:....|.::..|..........|......|.      |..|...:      |
  Rat   205 PDVKIKLKVQALIYPALQALDMNVPSQQENSQYPLLTRSLLIRF------WSEYFTTDRDLEKAM 263

  Fly   295 KWNYEIDGHFLH-----NHPTEL---IKEGNFNKVPLLISF-TANEF----DYNANVHLENQHLL 346
            ..|..:...|.|     |..:.|   .|:|.|.|.|...|. .|.::    |..|...|.|..:|
  Rat   264 LLNQHVPVEFSHLLQFVNWSSLLPQRYKKGYFYKTPTPGSLELAQKYPGFTDVKACPLLANDSIL 328

  Fly   347 HDFASNFVDYAPELFLYRHDAQIGEKLKDFYLGDNTTEINSENIENFGQIFSDAYIGHGVHRLVQ 411
            |.....::      ...::|.     |:|    |....:  :.::|.|...:..:|..|.|..:.
  Rat   329 HHLPMTYI------ITCQYDV-----LRD----DGLMYV--KRLQNTGVHVTHHHIEDGFHGALT 376

  Fly   412 L 412
            |
  Rat   377 L 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3841	NP_609300.1	COesterase	27..528	CDD:395084	89/430 (21%)
Aadac	NP_065413.1	Abhydrolase_3	106..373	CDD:400284	67/329 (20%)
		Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole. /evidence=ECO:0000250|UniProtKB:Q5NUF3	110..112		1/1 (100%)