DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3841 and tg

DIOPT Version :9

Sequence 1:	NP_001188759.1	Gene:	CG3841 / 34278	FlyBaseID:	FBgn0032131	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_001316794.1	Gene:	tg / 567631	ZFINID:	ZDB-GENE-030519-1	Length:	2733	Species:	Danio rerio

Alignment Length:	490	Identity:	143/490 - (29%)
Similarity:	222/490 - (45%)	Gaps:	71/490 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 LGRIQGDTMQSFGNKTIYAFRGIRYAQSPVGQLRFANPVPETSWGDEVFNATSDSLVCPQPGVV- 98
            ||..:...:....:|.:..|.|:.||:.|:|.|||:.|.|....|  .:|||.....|.|||.:
Zfish  2175 LGESEVKPITGSDSKRVTYFLGVPYARPPIGDLRFSPPQPADWTG--TWNATFFRSSCLQPGDLT 2237

  Fly    99 -SLMSEDCLKINVFTKSFEDK-FPVMVYIHGGANVLGSGHSSYEAGPQYLLDQDVVFVAFNYRLG 161
             |..|||||.:|||..|...| .||:|:.|...:.|..|  ||.|..     .:::.|..::|:.
Zfish  2238 DSSSSEDCLYLNVFVASSVAKNAPVLVFFHNSGSDLLDG--SYLAAV-----GNIIVVTASFRMA 2295

  Fly   162 ALGFLSTNSSETKGNFGFLDQVMALEWVRDHISHFGGDPELVTIIGISAGSMAVSLHLASPLSAG 226
            |.||||..||...||:|..||..||.||:.:|:.|||||..||:.....|:...||||.||.::.
Zfish  2296 AFGFLSAGSSALPGNYGLQDQAAALGWVQKNIALFGGDPTKVTVGAERNGADIASLHLTSPSASS 2360

  Fly   227 LFHRAILMSGSATNHFDIDN----LFWTRKLARELGCPMYDPTDVVECLR-------NETWTRIV 280
            ||.||:||.||..:...:.:    ...|..|||||.|...||:.:::|||       |...|:::
Zfish  2361 LFSRALLMGGSVFSPAVVMSSSKAQAQTSSLARELDCQAADPSQLLDCLRSKPAHSINAAQTKLL 2425

  Fly   281 EVCKAWETYQLVNMKWNYEIDGHFLHNHPTELIKEGNFNKVPLLISFTANEFDYNANVHLENQHL 345
            .|....:.       |:..:||:.:...|:..::.|.|:|..:|:..:..:...:...:::|...
Zfish  2426 AVSGPLQA-------WSPVVDGNVVREMPSVALQSGRFHKAEILLGSSFEDGLISRAKNIKNFEQ 2483

  Fly   346 LHDFASNFVDYAPEL--FLYRHDAQ--IGEKLKDFY-LGDNTT----EINSENIENFGQIFSDAY 401
            |...|.:...:...|  .|...||.  :.|....|| |..:.|    .:.|..:||..:   |.:
Zfish  2484 LQGRADSKTAFYAALSNSLGGDDANAFVKEAATWFYSLQHSPTPSGYNVFSRALENATR---DLF 2545

  Fly   402 IGHGVHRLVQLASHF-----TPVYYTRMDYVGDQSLSAPLNGENKPVGVGHADDLHYVLPGYWYG 461
            |   :...|.:|..:     |.||...:          |.|.....|.:....|:.|:     :|
Zfish  2546 I---ICPTVDMAEFWAANTQTGVYMYHL----------PENAAYNSVDLSVPMDVQYL-----FG 2592

  Fly   462 PLMAANDSDVFMMERLT------SWFTHFAKTGTP 490
            ..:||...|:|..:..|      ::..:|.|:|.|
Zfish  2593 VPLAAEQRDLFSYKEKTFTLQIMNYMANFIKSGNP 2627

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3841	NP_001188759.1	COesterase	27..528	CDD:278561	143/490 (29%)
CG3841	NP_001188759.1	Aes	<116..>235	CDD:223730	48/119 (40%)
tg	NP_001316794.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575633
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840