DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3841 and si:dkey-30c15.17

DIOPT Version :9

Sequence 1:	NP_001188759.1	Gene:	CG3841 / 34278	FlyBaseID:	FBgn0032131	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	XP_003200472.2	Gene:	si:dkey-30c15.17 / 561375	ZFINID:	ZDB-GENE-060503-450	Length:	657	Species:	Danio rerio

Alignment Length:	588	Identity:	156/588 - (26%)
Similarity:	239/588 - (40%)	Gaps:	148/588 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 GDDPVVELSLGRIQGDTMQSFGNKTIYAFRGIRYAQSPVGQLRFANPVPETSWGDEVFNATSDSL 90
            |.||||...|||::|.|::.     .:.|.||.||..|||..|:|.|.|.:.| ...:|||
Zfish   133 GADPVVVTLLGRVRGLTLEK-----AHVFYGIPYADPPVGDKRWAPPSPVSPW-LYTYNAT---- 187

  Fly    91 VCPQPGVVSL------------MSEDCLKINVFTKSFED-------KFPVMVYIHGGANVLGSGH 136
             .|:|..:.:            :|||||.:|||.....:       ..||||:||||..:.||..
Zfish   188 -FPRPACMQMCAGEFSRLCPPEVSEDCLYLNVFVPVSVNLSLPKVTALPVMVWIHGGDFIAGSAS 251

  Fly   137 SSYEAGPQYLLD-QDVVFVAFNYRLGALGFLSTN---SSETKGNFGFLDQVMALEWVRDHISHFG 197
            .....| :|:.: .:.|.|...|||||.|||.|.   .|...||:|.|||..||.||:::|:.||
Zfish   252 KPLYDG-RYISNYSNTVVVNMEYRLGAFGFLVTGKDPESSAVGNYGILDQQAALHWVQENIAAFG 315

  Fly   198 GDPELVTIIGISAGSMAVSLHLASPLSAGLFHRAILMSGSAT----NHFDIDNLFWTRKLARELG 258
            |||..||:.|.|||:.:|||||....|..||..|.:.|...:    ..:|...|.|  ..|:...
Zfish   316 GDPNKVTLFGESAGAQSVSLHLMMQSSETLFRHAAIQSLPFSLPLKTRWDAMKLGW--DFAKLTN 378

  Fly   259 CPMYDPTDVVECLRN-----------ETWTRIVEVCKAWETYQLVNMKWNYEIDGHFLHNHPTEL 312
            |.::|    :.|:|:           ::.::|:...:..|.::    .|...|||..|...|...
Zfish   379 CSVFD----LPCMRSLSSEDVLNAQIKSGSKIINPFRFLEVFE----TWGPFIDGQLLKEQPITA 435

  Fly   313 IKEGNFNKV-PLLISFTANE------FDYNANVHLENQHLLHDFASNFVDYAPELFLYRHDAQIG 370
            .::|::... |:::..|:.|      .::|.:|.:          ...|.|...:| .:|..:|.
Zfish   436 FQKGHWQSYKPVILGTTSEEGVMFVYRNFNKSVSM----------LECVLYTAAIF-KQHALKIL 489

  Fly   371 EKLKDFYLGDNTTEINSENIENFGQIFS-----DAYIGHGVHRLVQLASHFTPVYYTRMDYVGDQ 430
            .|...||...:...:.|:.:.::  :||     .|..|..|...|.:             ||.|.
Zfish   490 HKYIPFYRNQDRRVMLSQMVTDY--VFSCPARQSARSGVKVGGAVWM-------------YVFDH 539

  Fly   431 SLSAP-------------LNGENKPVGVGHADDLHYVLPGYWYGPLMAANDSDVFMMERLTSWFT 482
            :.|.|             .:|...|.....|...::..           ...:..:..|:..::.
Zfish   540 APSDPNIWAELTFCYNHSCHGAELPFLFDSAPSTNFTF-----------TPQERLLANRMACYWG 593

  Fly   483 HFAKTGTPLNSTD------------IWPPCNS----TVLKMLYNGVVTQVGSPGYSNR---YAVW 528
            .||.||.| ||.|            :||....    |:|.:      |....|.:.:|   ...|
Zfish   594 MFAHTGDP-NSRDEQTHFCREQRLPVWPRYTDIGGWTILNL------TLQSHPQHGSRDHFCDFW 651

  Fly   529 DKL 531
            |:|
Zfish   652 DRL 654

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3841	NP_001188759.1	COesterase	27..528	CDD:278561	152/582 (26%)
CG3841	NP_001188759.1	Aes	<116..>235	CDD:223730	55/129 (43%)
si:dkey-30c15.17	XP_003200472.2	COesterase	134..651	CDD:306613	152/582 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575414
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.840