DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3841 and Est-Q

DIOPT Version :9

Sequence 1:	NP_001188759.1	Gene:	CG3841 / 34278	FlyBaseID:	FBgn0032131	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_649321.1	Gene:	Est-Q / 40381	FlyBaseID:	FBgn0037090	Length:	559	Species:	Drosophila melanogaster

Alignment Length:	557	Identity:	170/557 - (30%)
Similarity:	251/557 - (45%)	Gaps:	127/557 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LLLILIGFTTA------VTFI----GDDP------VVELSLGRIQGDTMQSFG-----NKTIYAF 54
            ::|.|.|..||      |.|:    |.|.      .|||..|  ||..:.::.     ::....|
  Fly     8 VMLTLCGVLTAGLTAFLVIFLTGGQGADASETATVTVELYNG--QGTVLGNYAYTAWTDRAFMQF 70

  Fly    55 RGIRYAQSPVGQLRFANPVPETSWGDEVFNATSDSLVCPQ-PGVVSLMS----EDCLKINVFTKS 114
            |||.:|:.|:.:|||..||..:.| ....||.:....||. ..:.|.||    ||||.::|:||:
  Fly    71 RGIPFAEPPIEELRFRPPVARSPW-TGTLNALNFGQRCPVITNLDSQMSDAELEDCLTLSVYTKN 134

  Fly   115 FEDKFPVMVYIHGGANVLGSGHSSYEAGPQYLLDQDVVFVAFNYRLGALGFLSTNSSETKGNFGF 179
            .....|||.||:||....|   ||.:..|.|||::|||.|...||:||||:|||.:.|..||...
  Fly   135 LSASQPVMFYIYGGGFYNG---SSEDHPPNYLLEKDVVLVVPQYRVGALGWLSTYTEELPGNAPI 196

  Fly   180 LDQVMALEWVRDHISHFGGDPELVTIIGISAGSMAVSLHLASPLSA-GLFHRAILMSGS--ATNH 241
            .|.:|||:||:.|||.|||||:.|||.|.|||:...|..|.||.:. .:|.|||:.|||  |:..
  Fly   197 ADILMALDWVQMHISSFGGDPQKVTIFGQSAGAGVASSLLLSPKTGDNMFKRAIVQSGSIFASWA 261

  Fly   242 FDIDNLFWTRKLARELGCPMYDPTD-VVECLRNETWTRIVEVCKAW--ETYQ-LVNMKWNYEIDG 302
            .:.|....:|::..:|||...:..| :|:|::.   .:::::.||.  |::. :|.     ::.|
  Fly   262 INKDPKAQSRRICIQLGCSGCEQHDQLVKCIQK---AKVIDILKATASESFSPIVG-----DLHG 318

  Fly   303 HFLHNHPTELIKEGNFNKVPLLISFT-------------------AN-------EFDYNANVHLE 341
             .|...|:||:|... .::|:|..||                   ||       :|....|..:.
  Fly   319 -ILPQQPSELVKSYR-RQIPILTGFTQHDGSFVLASYYDALAAKVANVSSLSVRQFSQGINDLVN 381

  Fly   342 NQHLLHDFASNFVDYAPE-LFLYRHDAQIGEKLKDFYLGDNTTEINSENIENFGQIFSDAYIGHG 405
            :...|.|...|.:.:.|: |..:.|.|.:....      |.||.|..::
  Fly   382 DTSGLTDNILNRLLFKPQALNSHDHSAAVSSYF------DLTTNIFMKS---------------- 424

  Fly   406 VHRLVQLASHF------TPVY---------YTRMDYVGDQSLSAPLNGENKPVGVGHADDLHYVL 455
              .::.||:..      ||||         |||..|....| ..|.||     ||.|::|..|:.
  Fly   425 --PVITLATKMYTQQRSTPVYVYSFEYEGTYTRFGYEFGNS-HYPFNG-----GVHHSNDNIYLF 481

  Fly   456 PGYWYGPLMAANDSDVFMMERLTSWFTHFAKTGTPLN 492
            ..:   ||   ...|..|.:::...:|.||..|.|.|
  Fly   482 ATH---PL---EGQDTQMSQKMVDVWTSFAIEGVPRN 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3841	NP_001188759.1	COesterase	27..528	CDD:278561	162/531 (31%)
CG3841	NP_001188759.1	Aes	<116..>235	CDD:223730	59/119 (50%)
Est-Q	NP_649321.1	COesterase	39..544	CDD:278561	161/526 (31%)
Est-Q	NP_649321.1	Aes	<137..>240	CDD:223730	54/105 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	99	1.000	Inparanoid score	I1664
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43142
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
	8	7.960