Protein Alignment CG3841 and Ces3a

DIOPT Version :9

• Sequence 1: NP_001188759.1
• Gene: CG3841 / 34278
• FlyBaseID: FBgn0032131
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_941074.1
• Gene: Ces3a / 382053
• MGIID: 102773
• Length: 571
• Species: Mus musculus
• Alignment Length: 591
• Identity: 172/591 - (29%)
• Similarity: 255/591 - (43%)
• Gaps: 113/591 - (19%)

  Fly     9 WALLLILIGFTTAVTFIGDDPVVELSLGRIQG------DTMQSFGNKTIYAFRGIRYAQSPVGQL 67
            |...|:||..||.:......|.|:..|||::|      ||     ::.:..|.||.:||:|:|.|
Mouse    17 WMACLLLIFPTTVIGPKVTQPEVDTPLGRVRGRQVGVKDT-----DRMVNVFLGIPFAQAPLGPL 76

  Fly    68 RFANPVPETSWGDEVFNATSDSLVCPQPGVVSLM----------------SEDCLKINVFTK--- 113
            ||:.|:|...| :.|.:|:.:..:|.|.  |..|                |||||.:|:::.
Mouse    77 RFSAPLPPQPW-EGVRDASINPPMCLQD--VERMSNSRFTLNEKMKIFPISEDCLTLNIYSPTEI 138

  Fly   114 SFEDKFPVMVYIHGGANVLGSGHSSYEAGPQYLLDQDVVFVAFNYRLGALGFLSTNSSETKGNFG 178
            :..||.||||:||||:.::||  |:...|.......|||.|...||||..|||||......||.|
Mouse   139 TAGDKRPVMVWIHGGSLLVGS--STSHDGSALAAYGDVVVVTVQYRLGIFGFLSTGDKHMPGNRG 201

  Fly   179 FLDQVMALEWVRDHISHFGGDPELVTIIGISAGSMAVSLHLASPLSAGLFHRAILMSGSATNHFD 243
            |||.|.||.||:.:|:.|||||..|||.|.|||.:.||..|.||:|||||||||..||...:...
Mouse   202 FLDVVAALRWVQGNIAPFGGDPNCVTIFGNSAGGIIVSSLLLSPMSAGLFHRAISQSGVVISKIL 266

  Fly   244 IDNLFWT--RKLARELGCPMYDPTDVVECLRNETWTRIVEVCKAWETYQLVNMKWNYEIDGHFLH 306
            .|...|:  :..|..:.|....|.::|:||..:....::       |.:.||:  :|.::..|..
Mouse   267 EDLNAWSEAQNFANSVACGSASPAELVQCLLQKEGKDLI-------TKKNVNI--SYTVNDSFFP 322

  Fly   307 NHPTELIKEGNFNKVPLLISFTANEFDY---------NANVHLENQHLLHDFASNFVDYAPELFL 362
            ..|.:|:....|..||.|:..|.:||.:         :...||..:.||.       :..|.|..
Mouse   323 QRPQKLLANKQFPTVPYLLGVTNHEFGWLLLKFWNILDKMEHLSQEDLLE-------NSRPLLAH 380

  Fly   363 YRHDAQIGEKLKDFYLGDNTTEINSENIENFGQIFSDAYIGHGVHRLVQLASHFTPVYYTRM--D 425
            .:...:|...:.|.||.:.:.|..:.                  :.|.:|....|.|..|.:  .
Mouse   381 MQLPPEIMPTVIDEYLDNGSDESATR------------------YALQELLGDITLVIPTLIFSK 427

  Fly   426 YVGDQSLSAPLN---------GENKP--VGVGHADDLHYVLPGYWYGPLM-----------AAND 468
            |:.|......|.         .:.||  |...|:.:..:|    :.||.:           |..:
Mouse   428 YLQDAGCPVFLYEFQHTPSSFAKFKPAWVKADHSSENAFV----FGGPFLTDESSLLAFPEATEE 488

  Fly   469 SDVFMMERLTSWFTHFAKTGTPLNSTDI--WPPCNSTVLKMLYNGVVTQVGSPGYSNRYAVWDKL 531
            .....:..:..| :.||:||.| |...:  ||..|. :.:.|..|:..:.|......|...|.:.
Mouse   489 EKQLSLTMMAQW-SQFARTGNP-NGKGLPPWPQLNQ-LEQYLEIGLEPRTGVKLKKGRLQFWTET 550

  Fly   532 FPTAAQ 537
            .|...|
Mouse   551 LPRKIQ 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3841	NP_001188759.1	COesterase	27..528	CDD:278561	163/562 (29%)
		Aes	<116..>235	CDD:223730	65/118 (55%)
Ces3a	NP_941074.1	COesterase	36..547	CDD:278561	163/561 (29%)
		Aes	75..>245	CDD:223730	72/174 (41%)
		Prevents secretion from ER. /evidence=ECO:0000255	568..571

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832501
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	228	1.000	Inparanoid score	I3450
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D233524at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.800