DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3841 and cel.1

DIOPT Version :9

Sequence 1:	NP_001188759.1	Gene:	CG3841 / 34278	FlyBaseID:	FBgn0032131	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_955901.2	Gene:	cel.1 / 322481	ZFINID:	ZDB-GENE-030131-1201	Length:	550	Species:	Danio rerio

Alignment Length:	568	Identity:	146/568 - (25%)
Similarity:	239/568 - (42%)	Gaps:	145/568 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LILIG-FTTAVTFIGDDPVVELSL-----GRIQGDTMQSFGNKTIYAFRGIRYAQSPVGQLRFAN 71
            :.::| |.:||.|:|......|..     |.:||.:......:.:..|:||.:|..|   .||..
Zfish     1 MAMLGVFISAVLFLGTAQGASLGAVLTEGGMVQGKSRSVGLFRYMDTFKGIPFAAPP---KRFEK 62

  Fly    72 PVPETSWGDEVFNATSDSLVCPQPGVVS---LMSEDCLKINVFT---KSFEDKFPVMVYIHGGAN 130
            ||....| :.|...|.....|.|..:::   :.|||||.:|::.   ::.....||||:|:|||.
Zfish    63 PVAHPGW-EGVLKTTDYRKRCLQLNLLATDVIGSEDCLYLNIWVPQGRTVSSNLPVMVFIYGGAF 126

  Fly   131 VLGSGH-----SSYEAGPQYLLDQ-DVVFVAFNYRLGALGFLSTNSSETKGNFGFLDQVMALEWV 189
            :||.|.     .:|....:.:.|: :|:.|.||||:|||||:||......||:|..||..|:.||
Zfish   127 LLGGGQGANFLDNYLYDGEEMADRGNVIVVTFNYRVGALGFMSTGDDGIPGNYGLWDQHAAISWV 191

  Fly   190 RDHISHFGGDPELVTIIGISAGSMAVSLHLASPLSAGLFHRAILMSGSATNHFDIDN--LFWTRK 252
            ..:|..|||:|:.:|:.|.|||:.:|:..:.:|.:.|:..|||..||.|...:.|..  ..:..:
Zfish   192 HRNIKAFGGNPDNITLFGESAGAASVNFQIITPKNKGMIRRAISQSGVALCPWAISRNPRQFAEE 256

  Fly   253 LARELGCPMYDPTDVVECLRNE-----TWTRIVEVCKAWETYQLVNMKWNYEIDGHFLHNHPTEL 312
            :|.::|||:  .:.:.:||:..     |....:::..:.:...:.|:..:..|||.|:.:.|..|
Zfish   257 IATKVGCPI--DSGMADCLKRADPKAVTLAGKLKLTSSPDAPIVHNLYLSPVIDGDFIPDEPETL 319

  Fly   313 IKEGNFNKVPLLISFTANEFDYNANVHLENQHLLHDFA-------SNFVDYAP-------ELFLY 363
            .  ||           |.:.||.|.|:..:.|:   ||       :|.:...|       ...|.
Zfish   320 F--GN-----------AADIDYIAGVNDMDAHI---FATIDIPSINNALTTTPVEEVQALATALS 368

  Fly   364 R---HDAQIG---------------EKLKD------------------FYLGDNTTEINSENIEN 392
            |   .||.|.               ||:|.                  .||..:    |:::...
Zfish   369 RDRGQDAGIATFQEYTVNWGDKPNKEKVKQTVVELETDYMFLVPTQAALYLHTD----NAKSART 429

  Fly   393 FGQIFSDAYIGHGVHRLVQLASHFTPVYYTRMDYVGDQSLSAPLNGENKPVGVGHADDLHYVLPG 457
            |..:|::              |...||:              ||     .:|..|||:|.||...
Zfish   430 FSYLFTE--------------SSRIPVF--------------PL-----WMGADHADELQYVFGK 461

  Fly   458 YWYGPL---MAANDSDVFMMERLTSWFTHFAKTGTPLNSTD----IWP 498
            .:..||   ....|...:|:    :::::||:||.|.....    .||
Zfish   462 PFATPLGYFPRHRDVSKYMI----AYWSNFAQTGDPNKGESKVPVTWP 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3841	NP_001188759.1	COesterase	27..528	CDD:278561	140/553 (25%)
CG3841	NP_001188759.1	Aes	<116..>235	CDD:223730	50/124 (40%)
cel.1	NP_955901.2	COesterase	25..517	CDD:306613	139/544 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575555
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.740